Toxicology News and Research

Latest Toxicology News and Research

Wood stoves with chimneys linked to reduced childhood pneumonia

Cooking stoves with chimneys can lower exposure to indoor wood smoke and reduce the rate of severe pneumonia by 30 percent in children less than 18 months of age, according to a new air pollution study funded by the National Institute of Environmental Health Sciences (NIEHS), part of the National Institutes of Health.

11 Nov 2011

Aristolochic acid leads to kidney failure, upper urinary tract cancer

Aristolochic acid, a component of a plant used in herbal remedies since ancient times and still used in certain herbal medicines worldwide, leads to kidney failure and upper urinary tract cancer in individuals exposed to the toxin.

10 Nov 2011

Helping others helps adolescent helpers reduce cravings for alcohol and drugs

A new study of teens undergoing substance abuse treatment finds helping others helps the adolescent helper by reducing cravings for alcohol and drugs, a major precipitator of relapse.

9 Nov 2011

BioTime third quarter revenue increases 40% to $1.1 million

BioTime, Inc., a biotechnology company that develops and markets products in the field of regenerative medicine, today reported financial results for the third quarter and nine months ended September 30, 2011 and highlighted recent corporate accomplishments.

9 Nov 2011

Elsevier's 2012 eBook Frontlist collections available on SciVerse ScienceDirect

Elsevier, the world-leading publisher of scientific, technical and medical information products and services, announced today that its 2012 eBook Frontlist collections are available for advance purchase on SciVerse ScienceDirect, Elsevier's online platform for scientific content.

3 Nov 2011

Pacira's third quarter total revenues decrease to $4.0 million

Pacira Pharmaceuticals, Inc., an emerging specialty pharmaceutical company, today announced financial results for the third quarter ended September 30, 2011 and provided an update on the U.S. Food and Drug Administration's (FDA) approval of EXPAREL and the commercial strategy to support the product launch.

31 Oct 2011

BPA exposure in mothers may affect unborn daughters’ behavior: Study

A new federal study revealed Monday in the journal Pediatrics shows that bisphenol A (BPA) - a chemical used widely in plastic bottles, metal cans and other consumer products could be linked to behavioral and emotional problems in toddler girls.

25 Oct 2011

Research questions aromatherapy safety

Aromatherapy oils are relied upon to relax, reduce stress and soothe aches and pains by many. However researchers from Chia-Nan University of Pharmacy and Science Tainan, Taiwan say these oils may not be completely harmless.

24 Oct 2011

Comprehensive ADMESeq Research Screening Panel launched

RainDance Technologies, Inc., the Digital Biology Company, and Ambry Genetics, today announced the launch of a comprehensive targeted sequencing panel to screen genes involved with drug absorption, distribution, metabolism, and excretion (ADME) research. The ADMESeq Research Screening Panel enables researchers to simultaneously interrogate 242 known pharmacogenetic genes using next-generation sequencing (NGS) systems.

24 Oct 2011

Covance Shanghai facility receives OECD Good Laboratory Practice certification

Covance Inc. today announced that its early development facility located in Shanghai, China, has received Good Laboratory Practice (GLP) certification from the Belgian GLP Monitoring Authority, a member of the Organization for Economic Cooperation and Development (OECD). The Covance facility in Shanghai provides bioanalytical, toxicology, lead optimization toxicology, in-vivo PK screening, and metabolism services.

24 Oct 2011

First step in the development of new drug combinations against diseases, conditions

The researchers found a way of identifying ideal drug combinations from billions of others which would prevent inflammation from occurring.

From The University of Manchester 24 Oct 2011

New metabolic pathway for controlling brain inflammation

A team led by scientists from The Scripps Research Institute has identified a new metabolic pathway for controlling brain inflammation, suggesting strategies for treating it.

21 Oct 2011

JHU, Eisai enter drug-discovery research collaboration for brain disorders

The Johns Hopkins University (JHU) has entered into a drug-discovery research collaboration with Eisai, a pharmaceutical company based in Tokyo, to develop proprietary small-molecule drugs for a range of brain conditions such as schizophrenia, pain, brain tumors and Alzheimer's disease.

20 Oct 2011

Potential new protein target for pulmonary hypertension

A protein critical to development appears to have a grave impact on lungs exposed to smoking and air pollution, researchers report.

18 Oct 2011

FDA may be lax when it comes to laws on sea food safety: Study

Due to the last year’s BP oil spill in the Gulf of Mexico, a new study contends that current federal standards underestimate the risk to pregnant women and children of cancer-causing contaminants that can accumulate in seafood from such spills.

16 Oct 2011

Brain stem cell treatment for multiple sclerosis

The prospect of doing human clinical trials with stem cells to treat diseases like multiple sclerosis may be growing closer, say scientists at the University at Buffalo and the University at Rochester, who have developed a more precise way to isolate stem cells that will make myelin.

15 Oct 2011

Scientists characterize and isolate potential stem cells to treat MS, myelin disorders

Scientists have improved upon their own previous world-best efforts to pluck out just the right stem cells to address the brain problem at the core of multiple sclerosis and a large number of rare, fatal children's diseases.

14 Oct 2011

Study explores link between BPA exposure and breast cancer

Chronic low-level exposure to a compound found in a variety of plastic household items could pose a threat to women who overproduce a protein linked with breast cancer, say researchers at University of Alabama at Birmingham.

13 Oct 2011

FDA grants Advaxis pre-IND meeting for ADXS-HER2 cancer immunotherapy

Advaxis, Inc., a leader in developing the next generation of immunotherapies for cancer and infectious diseases, has been granted a pre-Investigational New Drug meeting with the U.S. Food and Drug Administration on November 22nd, 2011 to discuss the initial clinical development plan for ADXS-HER2, a construct for the treatment of HER2 expressing cancers.

12 Oct 2011

AIT Laboratories introduces new suite of services for prescription compliance monitoring

Chronic pain affects an estimated 116 million adults in the U.S.—more than the number affected by heart disease, diabetes, and cancer combined, according to a recent report by the Institute of Medicine.

10 Oct 2011