Toxicology News and Research

Latest Toxicology News and Research

Insight into relationship between two types of suppressors in cancerous tumors

The University of Kentucky has announced that Dr. Daret St. Clair, the James Graham Brown Endowed Chair and professor of toxicology, has published the first comprehensive study that provides insight into the relationship between two types of suppressors in cancerous tumors. The results will enhance the understanding of transcriptional mechanisms in carcinogenesis.

23 Feb 2012

UMMS' iHeal project uses emerging technologies to detect drug cravings and intervene

Clinical researchers at the University of Massachusetts Medical School (UMMS) are combining an innovative constellation of technologies such as artificial intelligence, smartphone programming, biosensors and wireless connectivity to develop a device designed to detect physiological stressors associated with drug cravings and respond with user-tailored behavioral interventions that prevent substance use.

22 Feb 2012

SOT 51st Annual Meeting and ToxExpo to be held March 11-15

The Society of Toxicology (SOT) 51st Annual Meeting and ToxExpo - the largest meeting and expo of its kind anywhere in the world - will take place from March 11-15. The five-day program will feature more than 180 sessions, presenting the latest research findings and recommendations for remedial action on a wide range of issues affecting human and animal health and the environment.

22 Feb 2012

Some answers about prescription psychiatric drugs

The circumstances of Whitney Houston's demise have dominated headlines and search trends since news outlets first reported of her death. Her struggle with addiction was covered extensively by the media, and even discussed candidly by Houston herself during several high-profile interviews.

20 Feb 2012

Arsenic found in baby formula containing organic brown rice syrup

Rice is among the plants that are efficient in taking up arsenic from the soil, environmental chemist Brian Jackson of Dartmouth College in Hanover, N.H., and his co-authors said in Thursday's issue of the journal Environmental Health Perspectives. Long-term exposure to extremely high levels of inorganic arsenic can increase the risk of lung, liver and bladder cancer as well as miscarriage and infertility.

18 Feb 2012

TRANSFUSION publishes positive results from CryoStor collaborative research

BioLife Solutions, Inc., a leading developer, manufacturer and marketer of proprietary clinical grade hypothermic storage and cryopreservation freeze media for cells and tissues, today announced that TRANSFUSION, the foremost publication in the world for new information regarding transfusion medicine, has published a peer-reviewed journal article reporting positive results of collaborative research on CryoStor, BioLife's serum-free, protein-free cryopreservation freeze media.

18 Feb 2012

Pharmos reports net loss of $0.4 million for fourth quarter 2011

Pharmos Corporation reported financial results for the fourth quarter and twelve-month period ended December 31, 2011. These results are included in the Company's Yearly Report on Form 10-K which has been filed with the SEC.

17 Feb 2012

Collaborative Cross can help fast-track key discoveries about genetics and disease

A series of 15 scientific papers published this week in the journals of the Genetics Society of America (Genetics and G3: Genes|Genomes|Genetics) put North Carolina at the epicenter of a scientific resource called the Collaborative Cross - a "library" of genetic diversity that scientists believe can help fast-track important discoveries about genetics and disease into new discoveries, tests, and treatments that impact human health.

17 Feb 2012

Exposure to common flame retardant may affect fertility and long-term memory

Mice genetically engineered to be susceptible to autism-like behaviors that were exposed to a common flame retardant were less fertile and their offspring were smaller, less sociable and demonstrated marked deficits in learning and long-term memory when compared with the offspring of normal unexposed mice, a study by researchers at UC Davis has found.

16 Feb 2012

BioCryst fourth quarter revenues decrease to $5.2 million

BioCryst Pharmaceuticals, Inc. announced financial results for the fourth quarter and full year ended December 31, 2011.

16 Feb 2012

Air pollution raises risk of stroke and cognitive decline

According to data from two studies published in the Archives of Internal Medicine exposure to air pollution may have serious cognitive and cardiovascular health consequences, even at levels currently deemed acceptable by the U.S. Environmental Protection Agency (EPA).

15 Feb 2012

400 lipsticks found to contain too much lead and could be harmful

Reuters first reported that a new study conducted by the FDA found that 400 lipsticks on the market tested positive for lead, according to the Campaign for Safe Cosmetics, a coalition that advocates for safer cosmetics and hygiene products.

15 Feb 2012

Karo Bio decides to discontinue development program for eprotirome

Karo Bio AB (publ) has decided to discontinue the development program for eprotirome after an animal study has demonstrated unwanted effects following long-term exposure. The planned spin-off of the preclinical part of operations will not proceed.

14 Feb 2012

Marshall University researcher to understand connections between cancer and obesity

A Marshall University researcher has been awarded a one-year, $60,000 grant from the Pharmaceutical Research and Manufacturers of America (PhRMA) Foundation.

14 Feb 2012

New iHeal project aims to detect drug cravings and prevent medication use

Imagine a device combining sensors to measure physiological changes. Then imagine a smartphone with software applications designed to respond to your bodily changes in an attempt to change your behavior. That is the vision behind "iHeal," currently being developed- by Edward Boyer from the University of Massachusetts Medical School in the US, and his colleagues.

9 Feb 2012

EpiCept seeks FDA Fast Track designation for AmiKet to treat CIPN

EpiCept Corporation today announced that it has filed for Fast Track designation for AmiKet(amitriptyline 4%, ketamine 2% cream) for the treatment for chemotherapy-induced peripheral neuropathy (CIPN) with the U.S. Food and Drug Administration.

7 Feb 2012

Pediatricians lead statewide effort to raise awareness about childhood vaccination

Two Saint Louis University pediatricians are leading a Missouri State Medical Association statewide effort to change the way doctors respond to parents' fears of vaccines, and to raise awareness about the importance of getting children vaccinated.

3 Feb 2012

Multiple DNA repair defect in monocytes

Scientists working with Professor Bernd Kaina of the Institute of Toxicology at the Medical Center of Johannes Gutenberg University Mainz have demonstrated for the first time that certain cells circulating in human blood - so-called monocytes - are extremely sensitive to reactive oxygen species (ROS).

3 Feb 2012

Researchers identify mechanism that leads to ischemia-reperfusion damage

For patients with incurable pulmonary conditions, a lung transplantation is the only available treatment option. However, suitable donor organs are scarce, and even getting them to prospective recipients is not easy. As Professor Alexander Dietrich of the Walther Straub Institute of Pharmacology and Toxicology at LMU explains, "An isolated lung which is no longer perfused with blood can become so severely damaged that it is no longer functional. This so-called ischemia-reperfusion injury is one of the major problems in the field of lung transplantation."

2 Feb 2012

Sigma-Aldrich acquires BioReliance

Sigma-Aldrich Corporation, a leading Life Science and High Technology company, announced it has completed its acquisition of BioReliance Holdings, Inc., a leading provider of global biopharmaceutical testing services, from Avista Capital Partners for $350 million in cash, subject to normal post-closing adjustments.

31 Jan 2012