Ulcerative Colitis News and Research

Latest Ulcerative Colitis News and Research

Novel method instructs immune cells to help repair damaged tissues in the intestine

A method that instructs immune system cells to help repair damaged tissues in the intestine has been developed by researchers at KU Leuven and Seoul National University.

8 Feb 2021

New diagnostic imaging tool measures naturally occurring enzymes in the gastrointestinal tract

A healthy person has a general balance of good and bad bacteria. But that balance is thrown off when someone gets sick.

5 Feb 2021

New partnership to develop test for predicting disease course in pediatric Crohn's patients

The Crohn's & Colitis Foundation, the leading non-profit organization focused on both research and patient support for inflammatory bowel disease (IBD), has entered into a partnership with LifeArc, an independent medical research charity that advances translation of early science into health care treatments or diagnostics, to potentially develop the first clinical lab test to predict disease course in pediatric patients with Crohn's disease and response to treatment.

25 Jan 2021

Researchers develop a novel, patient-derived model of ulcerative colitis

As reported in Nature Communications, researchers from Cleveland Clinic's Lerner Research Institute have developed a novel, patient-derived model of ulcerative colitis, which will help advance studies into new treatments for the chronic inflammatory bowel disease.

11 Jan 2021

Polygenic risk scores from multi-population data could improve IBD predictions

Using genetic data from nearly 30,000 people, Mount Sinai researchers have built risk scores from a combination of datasets representing distinct ancestral populations that improve prediction of risk for inflammatory bowel diseases (IBD) including Crohn's disease and ulcerative colitis. The study was published in Gastroenterology on December 24.

24 Dec 2020

Researchers demonstrate potential preventive treatment for Crohn's disease

A potential preventive treatment for Crohn's disease, a form of inflammatory bowel disease, has been demonstrated in a mouse model and using immune-reactive T cells from patients with Crohn's disease.

21 Dec 2020

Researchers pinpoint key factors to ensure successful fecal microbiota transplants

Could number two be number one when it comes to combating recurrent Clostridium difficile (CDI) infections?Using genetic material analysis and machine learning, UBC researchers have pinpointed several key factors to ensure successful fecal microbiota transplants (FMT), which have proven successful in treating bacterial infections in the gut including illnesses like C. difficile, Crohn's Disease, Colitis and even obesity, explains lead author Negin Kazemian.

10 Dec 2020

Study identifies genetic risk for fatal blood clots in IBD patients

Blood clots are the biggest cause of death in patients with inflammatory bowel disease (IBD) ─ ulcerative colitis or Crohn's disease. In a retrospective study recently published in the journal Gastroenterology, Cedars-Sinai investigators found that a combination of rare and common genetic variants in some IBD patients significantly increased their risk of developing clot-causing thromboembolic diseases.

11 Nov 2020

Researchers launch clinical trial to assess therapeutic drug monitoring for patients with inflammatory diseases

New research presented at ACR Convergence, the American College Rheumatology's annual meeting, showed that patients with rheumatic diseases whose infliximab treatment was individually assessed and adjusted with a new strategy called therapeutic drug monitoring did not achieve remission at higher rates compared to those who received standard care.

8 Nov 2020

New IBD safety registry established to support the completion of post-marketing safety requirements

The Pediatric IBD Foundation, ImproveCareNow, and the Critical Path Institute (C-Path) are proud to announce a collaboration establishing the Children's Registry for the Advancement of Therapeutics (CREATE™).

6 Nov 2020

Study suggests a role for the hypothalamus in genetic susceptibility to IBD

Using sophisticated 3D genomic mapping and integrating with public data resulting from genome-wide association studies, researchers at Children's Hospital of Philadelphia have found significant genetic correlations between inflammatory bowel disease and stress and depression.

29 Oct 2020

Severe ulcerative colitis linked to a newly-discovered strain of oral bacteria

Bacteria from the mouth could hold clues to understanding – and potentially treating – severe ulcerative colitis, a painful bowel disease.

29 Oct 2020

People with depression are more likely to develop Crohn's disease

A new study, published inGut, has found depression is more common among people with Crohn's disease or ulcerative colitis in the years before they are diagnosed with these bowel conditions.

28 Oct 2020

Readers and tweeters shed light on vaccine trials and bias in health care

In the piece about the AstraZeneca vaccine trial subject who suffered severe spinal cord inflammation, that person was repeatedly referred to as a "patient" ("NIH 'Very Concerned' About Serious Side Effect in Coronavirus Vaccine Trial," Sept. 14).

28 Oct 2020

Intestinal microbiota offers new prospects for treating celiac disease

Celiac disease is an immune disease of the intestine that affects more than 1% of the population. It is characterised by gluten intolerance that causes inflammation of the gut, abdominal pain and diarrhoea, and can lead to weight loss and deficiencies among patients.

23 Oct 2020

Tryptophan found in turkeys can accelerate intestinal healing in people with celiac disease

People with celiac disease may find themselves more comfortable with extra Thanksgiving turkey dinners.An international team of researchers led by McMaster University has found that tryptophan, an amino acid present in high amounts in turkey, along with some probiotics, may help them heal and respond better to a gluten-free diet.

22 Oct 2020

Researchers identify pathogen responsible for creeping migration of fat in Crohn's patients

In many patients with Crohn's disease, abdominal fat migrates to the wall of the inflamed small intestines. What prompts the fat tissue to "creep" through the abdomen and wrap around the intestines of many patients with this inflammatory bowel disease (IBD) has been an enduring mystery.

1 Oct 2020

Study shows tofacitinib drug can repair permeability defects in the intestine

A team of researchers led by biomedical scientist Declan F. McCole at the University of California, Riverside, has found that the drug tofacitinib, also called Xeljanz and approved by the FDA to treat rheumatoid arthritis and ulcerative colitis, can repair permeability defects in the intestine.

30 Sep 2020

Wearable device tracks biomarkers in sweat associated with inflammatory bowel disease

University of Texas at Dallas researchers have designed a wearable device that monitors sweat for biomarkers that could signal flare-ups of inflammatory bowel disease (IBD).

28 Sep 2020

Multifunctional cell therapy system raises hopes to treat inflammatory bowel disease

The research by the UPV/EHU-University of the Basque Country, in collaboration with Harvard University, has yielded highly encouraging results, and studies in animal models have already begun

28 Sep 2020

Ulcerative Colitis News and Research

Latest Ulcerative Colitis News and Research

Novel method instructs immune cells to help repair damaged tissues in the intestine

New diagnostic imaging tool measures naturally occurring enzymes in the gastrointestinal tract

New partnership to develop test for predicting disease course in pediatric Crohn's patients

Researchers develop a novel, patient-derived model of ulcerative colitis

Polygenic risk scores from multi-population data could improve IBD predictions

Researchers demonstrate potential preventive treatment for Crohn's disease

Researchers pinpoint key factors to ensure successful fecal microbiota transplants

Study identifies genetic risk for fatal blood clots in IBD patients

Researchers launch clinical trial to assess therapeutic drug monitoring for patients with inflammatory diseases

New IBD safety registry established to support the completion of post-marketing safety requirements

Study suggests a role for the hypothalamus in genetic susceptibility to IBD

Severe ulcerative colitis linked to a newly-discovered strain of oral bacteria

People with depression are more likely to develop Crohn's disease

Readers and tweeters shed light on vaccine trials and bias in health care

Intestinal microbiota offers new prospects for treating celiac disease

Tryptophan found in turkeys can accelerate intestinal healing in people with celiac disease

Researchers identify pathogen responsible for creeping migration of fat in Crohn's patients

Study shows tofacitinib drug can repair permeability defects in the intestine

Wearable device tracks biomarkers in sweat associated with inflammatory bowel disease

Multifunctional cell therapy system raises hopes to treat inflammatory bowel disease

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

Ulcerative Colitis News and Research

Latest Ulcerative Colitis News and Research

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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