Ulcerative Colitis

Ulcerative colitis is a common inflammatory disease of the colon characterized by inflammation and ulceration of the large bowel and rectum. The condition impairs the ability of the large bowel to absorb water which results in diarrhea, the main symptom of the condition.

Ulcerative colitis is a relapsing and remitting condition, meaning symptoms can die down for long periods but then flare-up from time to time. These flare-ups can be sudden and severe. During a period of relapse, symptoms may include bloody diarrhea, abdominal pain and a sudden urge to defecate. Other symptoms include wind, loss of appetite, weight loss, fever and fatigue.

Currently, there is no cure for the condition apart from surgery. However, certain treatments such as corticosteroids or immunosuppressants may be used to ease symptoms by reducing inflammation. Surgery for severe ulcerative colitis that does not respond to treatment involves completely removing the large bowel and re-routing the small bowel so that waste can still be expelled. This procedure is called a colectomy.

In the UK, the incidence of ulcerative colitis is around 1 in 500 and the condition is equally common among males and females. Symptoms can develop at any age, but onset usually occurs between 15 and 30 years of age.
What is Ulcerative Colitis?

Ulcerative colitis is a chronic condition that affects the large intestines, particularly the colon. It is classified as one of the two inflammatory bowel diseases along with Crohn’s disease.

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Overview

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Latest Ulcerative Colitis News and Research

People with depression are more likely to develop Crohn's disease

People with depression are more likely to develop Crohn's disease

Readers and tweeters shed light on vaccine trials and bias in health care

Readers and tweeters shed light on vaccine trials and bias in health care

Intestinal microbiota offers new prospects for treating celiac disease

Intestinal microbiota offers new prospects for treating celiac disease

Tryptophan found in turkeys can accelerate intestinal healing in people with celiac disease

Tryptophan found in turkeys can accelerate intestinal healing in people with celiac disease

Researchers identify pathogen responsible for creeping migration of fat in Crohn's patients

Researchers identify pathogen responsible for creeping migration of fat in Crohn's patients

Study shows  tofacitinib drug can repair permeability defects in the intestine

Study shows tofacitinib drug can repair permeability defects in the intestine

Wearable device tracks biomarkers in sweat associated with inflammatory bowel disease

Wearable device tracks biomarkers in sweat associated with inflammatory bowel disease

Multifunctional cell therapy system raises hopes to treat inflammatory bowel disease

Multifunctional cell therapy system raises hopes to treat inflammatory bowel disease

Treatment with a cannabinoid prevented the development of colon cancers in mice

Treatment with a cannabinoid prevented the development of colon cancers in mice

Study shows lack knowledge about colonoscopy among high-risk patients

Study shows lack knowledge about colonoscopy among high-risk patients

Scientists discover tissue reparative role for a rare immune cell type in the gut

Scientists discover tissue reparative role for a rare immune cell type in the gut

Lasting nature of IBD linked to a long-lived immune cell that provokes damaging inflammation

Lasting nature of IBD linked to a long-lived immune cell that provokes damaging inflammation

Researchers identify a useful biomarker for intestinal diseases

Researchers identify a useful biomarker for intestinal diseases

New computational model can help determine drug viability

New computational model can help determine drug viability

Finding the right treatment for people with IBD may soon become easier

Finding the right treatment for people with IBD may soon become easier

Study may lead to more effective treatments for chronic intestinal inflammation

Study may lead to more effective treatments for chronic intestinal inflammation

Chronic inflammation associated with IBD disrupts tissue structure of the colon, study finds

Chronic inflammation associated with IBD disrupts tissue structure of the colon, study finds

First microbiome study of Irish Travelers provides important new health insights

First microbiome study of Irish Travelers provides important new health insights

High fiber diet may improve the quality of life for patients with ulcerative colitis

High fiber diet may improve the quality of life for patients with ulcerative colitis

Irritable bowel disease heightens the risk of dementia

Irritable bowel disease heightens the risk of dementia