Ulcerative Colitis

Ulcerative colitis is a common inflammatory disease of the colon characterized by inflammation and ulceration of the large bowel and rectum. The condition impairs the ability of the large bowel to absorb water which results in diarrhea, the main symptom of the condition.

Ulcerative colitis is a relapsing and remitting condition, meaning symptoms can die down for long periods but then flare-up from time to time. These flare-ups can be sudden and severe. During a period of relapse, symptoms may include bloody diarrhea, abdominal pain and a sudden urge to defecate. Other symptoms include wind, loss of appetite, weight loss, fever and fatigue.

Currently, there is no cure for the condition apart from surgery. However, certain treatments such as corticosteroids or immunosuppressants may be used to ease symptoms by reducing inflammation. Surgery for severe ulcerative colitis that does not respond to treatment involves completely removing the large bowel and re-routing the small bowel so that waste can still be expelled. This procedure is called a colectomy.

In the UK, the incidence of ulcerative colitis is around 1 in 500 and the condition is equally common among males and females. Symptoms can develop at any age, but onset usually occurs between 15 and 30 years of age.
What is Ulcerative Colitis?

Ulcerative colitis is a chronic condition that affects the large intestines, particularly the colon. It is classified as one of the two inflammatory bowel diseases along with Crohn’s disease.

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Latest Ulcerative Colitis News and Research

Broccoli and sprouts improve gut microbiota and reduce inflammation in IBD

Broccoli and sprouts improve gut microbiota and reduce inflammation in IBD

Study: Nearly 1 in 7 Americans regularly experience bloating issues

Study: Nearly 1 in 7 Americans regularly experience bloating issues

Biologic therapy for IBD patients through a financial assistance program could have superior outcomes

Biologic therapy for IBD patients through a financial assistance program could have superior outcomes

Well-equipped gut-friendly bacteria hold promise for improving IBD treatments

Well-equipped gut-friendly bacteria hold promise for improving IBD treatments

Microscopic IBD inflammation linked to women's elevated risk of giving birth preterm

Microscopic IBD inflammation linked to women's elevated risk of giving birth preterm

Researchers study the unique adaptability of small intestinal bacteria for the first time

Researchers study the unique adaptability of small intestinal bacteria for the first time

COVID-19 and the gut

COVID-19 and the gut

Research proposes a set of conditions that could be the starting point for ulcerative colitis

Research proposes a set of conditions that could be the starting point for ulcerative colitis

Pain-sensing neurons protect the gut from inflammation and associated tissue damage

Pain-sensing neurons protect the gut from inflammation and associated tissue damage

Certain types of dietary fiber fuel inflammation in some people with inflammatory bowel disease

Certain types of dietary fiber fuel inflammation in some people with inflammatory bowel disease

Mount Sinai study suggests significant role of reactive oxygen species in maintaining healthy intestines

Mount Sinai study suggests significant role of reactive oxygen species in maintaining healthy intestines

The compositional and functional diversity of the gut fungal microbiome

The compositional and functional diversity of the gut fungal microbiome

Study establishes a feasible combination therapeutic strategy for ulcerative colitis

Study establishes a feasible combination therapeutic strategy for ulcerative colitis

New capsule tunnels through mucus in the GI tract to deliver large protein drugs

New capsule tunnels through mucus in the GI tract to deliver large protein drugs

Understanding what happens when two gut microbiomes clash together

Understanding what happens when two gut microbiomes clash together

Recent literature reports on the role of the gut microbiome on human health and its effect on diseases

Recent literature reports on the role of the gut microbiome on human health and its effect on diseases

Discovery sheds light on an important aspect of gut health and mucosal immunity

Discovery sheds light on an important aspect of gut health and mucosal immunity

Researchers identify multiple genes and rare variants linked with Crohn's disease susceptibility

Researchers identify multiple genes and rare variants linked with Crohn's disease susceptibility

World's first-in-human research using organoid transplantation yields good results

World's first-in-human research using organoid transplantation yields good results

Oral chlorophyllin supplement alleviates inflammatory bowel disease

Oral chlorophyllin supplement alleviates inflammatory bowel disease