Vaccine News and Research

Latest Vaccine News and Research

Researchers take steps to standardize correlates of protection against SARS-CoV-2

Antibodies, Antibody, Assay, Coronavirus, Efficacy, Healthcare, Pandemic, Protein, Receptor, Research, Vaccine, Virus, Coronavirus Disease COVID-19,

24 May 2021

Little evidence for mRNA COVID-19 vaccine-associated thrombocytopenia, suggests new FDA study

Even as a host of vaccines have been rolled out to counter the coronavirus disease 2019 (COVID-19) pandemic, some serious adverse effects have been reported, in the form of thrombocytopenia. A new study in the journal Vaccine reports the results of an evaluation of reported cases of this condition, using data from the Vaccine Adverse Event Reporting System (VAERS).

24 May 2021

Novel natural compounds may help treat COVID-19, study suggests

A new study in the journal Chemistry Europe reports two natural compounds identified by virtual screening and computational modeling as having great promise for the development of drugs against SARS-CoV-2.

24 May 2021

Reduced levels of leptin are linked to poor vaccine responses in general population

Reduced levels of a metabolic hormone known as leptin is linked to poor vaccine antibody responses in the general population, a University of Queensland study has found.

24 May 2021

Could saffron be an effective supplement for helping manage COVID-19?

A new study, published in the journal Cell Press, explores the potential use of saffron (Crocus sativus L.) as a drug supplement for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19).

24 May 2021

Researchers identify aluminum hydroxide/TLR9 agonist as potential adjuvant to improve RBD-based COVID-19 vaccine efficacy

The study findings reveal that RBD-based vaccines adjuvanted with the formulation can induce strong anti-SARS-CoV-2 neutralizing immunity in young and aged mice. The study is currently available on the bioRxiv* preprint server.

24 May 2021

Researchers identify factors influencing vaccine hesitancy in USA

A team of scientists from the Washington University, in St. Louis, USA, has recently conducted a survey to analyze factors responsible for coronavirus disease 2019 (COVID-19) vaccination hesitancy among US citizens.

24 May 2021

SARS-CoV-2 mutations strengthen RBD-ACE2 binding, making the virus more infectious

In January 2020, the first complete severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) genome sequence was deposited to GenBank. Since then, the amount of new genome sequences has increased rapidly at GenBank and GISAID. This has laid the foundations for analyzing the virulence, antigenicity, pathogenicity, and transmissibility of SARS-CoV-2 mutations.

22 May 2021

High seroprevalence in Peruvian population recovering from SARS-CoV-2 infection

By the middle of 2020, Iquitos, Peru, had the highest number of SARS-CoV-2 antibodies in the world. Despite natural immunity, the city experienced a second coronavirus wave, with reinfections possibly owing to the P.1 variant.

22 May 2021

Papers that are less likely to be true are often the most cited in academic research

Papers in leading psychology, economic and science journals that fail to replicate and therefore are less likely to be true are often the most cited papers in academic research, according to a new study by the University of California San Diego's Rady School of Management.

22 May 2021

Australian discovery could speed up SARS-CoV-2 vaccine development

To address this gap, researchers from Australia recently examined the relationship between levels of in vitro neutralization and the observed protection obtained from SARS-CoV-2 infection. They used data from 7 currently available vaccines and convalescent cohorts. Their research is published in the journal Nature Medicine.

22 May 2021

Plant-based vaccine against SARS-CoV-2 shows promise

Researchers at Canadian biotechnology company Medicago report that Phase 1 trials of a plant-based vaccine for SARS-CoV-2 are underway and showing promise.

21 May 2021

If you are vaccinated, you can dance the night away

Marissa Castrigno was walking through downtown Wilmington, North Carolina, when she spotted the sign in the window of one of her favorite dance clubs.

21 May 2021

Parents and young adults urged to get HPV vaccination back on track

Sanford Burnham Prebys has joined doctors and scientists across America at National Cancer Institute (NCI)-designated cancer centers and other organizations to issue a joint statement urging the nation's physicians, parents and young adults to get the human papillomavirus (HPV) vaccination back on track.

21 May 2021

Novel broad-spectrum antiviral compounds effective against Zika and SARS-CoV-2

A research team at the University of Alberta, Canada, led by Dr. Daniel Limonta, has described two novel molecules with broad antiviral properties that are effective against a range of virus types, including SARS-CoV-2.

21 May 2021

How do common mutations in SARS-CoV-2’s spike affect its binding affinity with host cell receptors?

Antibodies produced during a previous case of COVID-19 or vaccine-induced immunity are targeted towards S protein, where the neutralizing antibodies attach to the Spike RBD domain. Some of the variants have mutations in their RBD domain, causing resistance to the neutralizing antibodies. However, the effect of these mutations on the affinity and kinetics of the binding of Spike RBD to ACE2 is not clear. A new study has been published on the bioRxiv* preprint server, which deals with the study of affinity and kinetic analysis of the interface between Spike RBD and ACE2 at physiological temperatures.

21 May 2021

Pfizer-BioNTech vaccination not associated with platelet activation in new study

Among the devastating complications of severe or critical coronavirus disease 2019 (COVID-19), clot formation ranks high in the adverse impact it creates. An important question is whether SARS-CoV-2-spike-based vaccines also cause such coagulopathies. A new study, released as a preprint on the medRxiv* server, examines this risk for the first time.

21 May 2021

Facets of SARS-CoV-2 infection and animal models

A new study in the journal Frontiers in Cell and Developmental Biology discusses the ribonucleic acid (RNA) genome of the virus, and the mechanisms by which it establishes infection within the host cell. The researchers also summarize the development of animal models of COVID-19, which will both help understand the clinical features of the illness, and indicate new approaches for the treatment of the infection.

21 May 2021

Despite frequent vaccinations, COVID-19 could continue to cause recurrent waves and deaths

Covid-19 could continue to cause recurrent waves and deaths despite frequent vaccinations according to a new study from the University of East Anglia.

21 May 2021

Metal complexes against coronavirus

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused more than 3.42 million deaths worldwide. Despite the fact that there are vaccines for SARS-CoV-2, the emergence of new variants and the lack of adequate treatments have encouraged the search for new ways to combat this disease more effectively.

21 May 2021

Vaccine News and Research

Latest Vaccine News and Research

Researchers take steps to standardize correlates of protection against SARS-CoV-2

Little evidence for mRNA COVID-19 vaccine-associated thrombocytopenia, suggests new FDA study

Novel natural compounds may help treat COVID-19, study suggests

Reduced levels of leptin are linked to poor vaccine responses in general population

Could saffron be an effective supplement for helping manage COVID-19?

Researchers identify aluminum hydroxide/TLR9 agonist as potential adjuvant to improve RBD-based COVID-19 vaccine efficacy

Researchers identify factors influencing vaccine hesitancy in USA

SARS-CoV-2 mutations strengthen RBD-ACE2 binding, making the virus more infectious

High seroprevalence in Peruvian population recovering from SARS-CoV-2 infection

Papers that are less likely to be true are often the most cited in academic research

Australian discovery could speed up SARS-CoV-2 vaccine development

Plant-based vaccine against SARS-CoV-2 shows promise

If you are vaccinated, you can dance the night away

Parents and young adults urged to get HPV vaccination back on track

Novel broad-spectrum antiviral compounds effective against Zika and SARS-CoV-2

How do common mutations in SARS-CoV-2’s spike affect its binding affinity with host cell receptors?

Pfizer-BioNTech vaccination not associated with platelet activation in new study

Facets of SARS-CoV-2 infection and animal models

Despite frequent vaccinations, COVID-19 could continue to cause recurrent waves and deaths

Metal complexes against coronavirus

Event guide: 3rd mRNA Process Development & Manufacturing Europe eBook

How the Vutara VXL simplifies single-molecule imaging

How cohesin mechanics and nanotracker tech are redefining DNA research

Todd Bauman and Chris Povich

Vaccine News and Research

Latest Vaccine News and Research

Event guide: 3rd mRNA Process Development & Manufacturing Europe eBook

How the Vutara VXL simplifies single-molecule imaging

How cohesin mechanics and nanotracker tech are redefining DNA research

Todd Bauman and Chris Povich

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