Vaccine News and Research

Latest Vaccine News and Research

SARS-CoV-2 spike E484K mutation reduces antibody neutralization

Researchers at the Department of Microbiology, Icahn School of Medicine at Mount Sinai New York, USA, showed that the SARS-CoV-2 spike E484K mutation reduces antibody neutralization.

12 Apr 2021

Researchers work to develop dual antigen COVID-19 vaccine candidate

A new study has been published on the medRxiv* preprint server, which focuses on the development of a dual-antigen COVID-19' T cell' vaccine. This vaccine is developed based on the expression of both S protein and nucleocapsid (N) protein of SARS-CoV-2, using a next-generation human adenovirus serotype 5 (Ad5) platform.

12 Apr 2021

Could N protein-based COVID-19 vaccines hinder SARS-CoV-2's NK cell inhibition?

Upon SARS-CoV-2 infection, what are the changes occurring on the surface of the host cell? To address this, and a team of researchers undertook a study exploring the natural killer (NK) cells and their role during a SARS-CoV-2 infection.

12 Apr 2021

Commercial assays detect mRNA-1273 and BNT162b2 vaccine-induced SARS-CoV-2 antibodies in most vaccinated participants

A recent study by researchers from Canada aimed to examine the ability of commercial assays to detect vaccine-induced antibodies and recognize the vaccination response.

12 Apr 2021

GACVS COVID-19 reviews rare cases of blood clots following AstraZeneca COVID-19 vaccination

The COVID-19 subcommittee of the WHO Global Advisory Committee on Vaccine Safety (GACVS) has reviewed reports of rare cases of blood clots with low platelets following vaccination with the AstraZeneca COVID-19 vaccine (including Covishield) since their onset a few weeks ago.

12 Apr 2021

More than 100 economies receive life-saving COVID-19 vaccines from COVAX

More than one hundred economies have received life-saving COVID-19 vaccines from COVAX, the global mechanism for equitable access to COVID-19 vaccines. The milestone comes 42 days after the first COVAX doses were shipped and delivered internationally, to Ghana on 24 February 2021.

12 Apr 2021

The role and ancestry of the SARS-CoV-2 spike protein glycan shield

In a research paper recently uploaded to the preprint server bioRxiv by Harbison et al. (April 1st 2021) a set of multi-microsecond long molecular dynamics simulations study the effects of altering glycosylation at sites N234, N165, N343, and the newly identified ancestral site N370, uncovering the influence of these sites on infectivity.

12 Apr 2021

mRNA-based COVID-19 vaccination during pregnancy provides passive SARS-CoV-2 immunity to neonates 16 days after first dose

Recently, a group of researchers analyzed 122 pregnant women and their neonates at the time of birth. All the women studied received 1 or both doses of a messenger RNA (mRNA)-based vaccine for COVID-19. Of the 122 women part of the study, 55 had received only the first dose of the vaccine while 67 women had received both doses of the mRNA vaccine by the time they gave birth; 85 women had received the Pfizer-BioNTech vaccine, and 37 women received the Moderna vaccine. The study is published on the preprint server, bioRxiv.

11 Apr 2021

Pregnant women transmit SARS-CoV-2 and vaccine-induced antibodies to fetus

Pregnant women are at high risk for severe COVID-19 infection and death. Yet, insufficient safety data on babies has led many guidelines to leave the decision-making and potential threats to future mothers. While the vaccine trials did not directly test pregnant women, more real-world data suggests the vaccine may provide immunity benefits to newborns through breastmilk.

11 Apr 2021

Broadly neutralizing antibodies show promise in preventing tick-borne encephalitis in mice

Tick-borne encephalitis is a disease just as nasty as it sounds. Once bitten by an infected tick, some people develop flu-like symptoms that resolve quietly but leave behind rampant neurological disease--brain swelling, memory loss, and cognitive decline.

9 Apr 2021

Analysis highlights the need for a more nuanced approach to COVID-19 vaccine prioritization

It's time for a more nuanced approach to vaccine prioritization, as more contagious COVID-19 variants become prevalent and a third wave of infections threatens to overwhelm hospitals in some provinces, according to an analysis published today in the Canadian Medical Association Journal.

9 Apr 2021

COVID-19 vaccine may precipitate the development of functional neurological disorder

Videos of people experiencing severe neurological symptoms, including convulsions and difficulty walking, purportedly after receiving a COVID-19 vaccine, have surfaced on Facebook, YouTube and other social media channels.

9 Apr 2021

Researchers use genetics to identify potential drugs for early management of COVID-19

A new study using human genetics suggests researchers should prioritize clinical trials of drugs that target two proteins to manage COVID-19 in its early stages.

9 Apr 2021

Canada should take a more nuanced approach when setting SARS-CoV-2 vaccine priorities

When setting SARS-CoV-2 vaccine priorities, Canada should take a more nuanced approach that considers geographic and occupational risk exposures, as 75% of Canadian adults have at least 1 risk factor for severe COVID-19, argues an analysis in CMAJ.

9 Apr 2021

WHO calls for urgent action to improve health for all people

COVID-19 has unfairly impacted some people more harshly than others, exacerbating existing inequities in health and welfare within and between countries. For World Health Day, 7 April 2021, WHO is therefore issuing five calls for urgent action to improve health for all people.

9 Apr 2021

Vaccine News and Research

Latest Vaccine News and Research

SARS-CoV-2 spike E484K mutation reduces antibody neutralization

Researchers work to develop dual antigen COVID-19 vaccine candidate

Could N protein-based COVID-19 vaccines hinder SARS-CoV-2's NK cell inhibition?

Commercial assays detect mRNA-1273 and BNT162b2 vaccine-induced SARS-CoV-2 antibodies in most vaccinated participants

GACVS COVID-19 reviews rare cases of blood clots following AstraZeneca COVID-19 vaccination

More than 100 economies receive life-saving COVID-19 vaccines from COVAX

The role and ancestry of the SARS-CoV-2 spike protein glycan shield

mRNA-based COVID-19 vaccination during pregnancy provides passive SARS-CoV-2 immunity to neonates 16 days after first dose

Pregnant women transmit SARS-CoV-2 and vaccine-induced antibodies to fetus

Broadly neutralizing antibodies show promise in preventing tick-borne encephalitis in mice

Analysis highlights the need for a more nuanced approach to COVID-19 vaccine prioritization

COVID-19 vaccine may precipitate the development of functional neurological disorder

Researchers use genetics to identify potential drugs for early management of COVID-19

Canada should take a more nuanced approach when setting SARS-CoV-2 vaccine priorities

WHO calls for urgent action to improve health for all people

Nine out of ten Danes show willingness to accept the COVID-19 vaccine

Researchers identify several novel SARS-CoV-2 inhibitors

Fauci thanks US health workers for sacrifices but admits PPE shortages drove up death toll

Does natural infection with SARS-CoV-2 offer more protection than a vaccine against new variants?

Serum and breast milk SARS-CoV-2 antibodies correlated in vaccinated mothers

Event guide: 3rd mRNA Process Development & Manufacturing Europe eBook

How the Vutara VXL simplifies single-molecule imaging

How cohesin mechanics and nanotracker tech are redefining DNA research

Todd Bauman and Chris Povich

Vaccine News and Research

Latest Vaccine News and Research

Event guide: 3rd mRNA Process Development & Manufacturing Europe eBook

How the Vutara VXL simplifies single-molecule imaging

How cohesin mechanics and nanotracker tech are redefining DNA research

Todd Bauman and Chris Povich

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