Vaccine News and Research

Latest Vaccine News and Research

Discovery of novel hidden gene in SARS-CoV-2

A team of researchers from Germany, Taiwan, and the United States has identified and characterized a new hidden gene in SARS-CoV-2 that is also present in Guangxi pangolin coronaviruses – though, curiously, absent in closely related pangolin and bat coronaviruses.

11 Nov 2020

Spike-based DNA vaccine shows excellent protection against SARS-CoV-2 in a hamster model

A study conducted at the United States Army Research Institute of Infectious Diseases shows how a relatively simple full-length DNA vaccine against spike glycoprotein of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can elicit neutralizing antibody response in an animal model – even after a single shot with simple jet injection technique.

11 Nov 2020

WHO Member States designate 2021 as the 'International Year of Health and Care Workers'

Member States at the resumed virtual, 73rd World Health Assembly, recognizing the dedication and sacrifice of the millions of health and care workers at the forefront of the Covid-19 pandemic, unanimously designated 2021 as the International Year of Health and Care Workers.

11 Nov 2020

Five important questions about Pfizer’s COVID-19 vaccine

Pfizer's announcement on Monday that its COVID-19 shot appears to keep nine in 10 people from getting the disease sent its stock price rocketing. Many news reports described the vaccine as if it were our deliverance from the pandemic, even though few details were released.

11 Nov 2020

A promising vaccine for treating poorly immunogenic tumors

Patients with cancer have multiple treatment options available to them today, but each has its drawbacks. Chemotherapy kills rapidly dividing cancer cells, but it also damages healthy cells in the body and often does not effectively prevent tumor metastasis or disease recurrence.

11 Nov 2020

Cabotegravir highly effective in preventing HIV among women

UNAIDS has been strongly encouraged by groundbreaking new study results showing that the antiretroviral medicine cabotegravir administered by an injection every two months – prevents HIV among women.

10 Nov 2020

Promising new antivirals target arboviruses and SARS-CoV-2: Nodosome inhibitors

A new study describes two promising small molecules that inhibit a host cell factor, called nucleotide binding oligomerization domain-containing protein 2 (NOD2), that inhibits the replication and spread of many arboviruses. This could lead to the development of broad-spectrum antivirals. The study's findings have been published on the preprint server bioRxiv*.

10 Nov 2020

Clinical study of personalized cancer vaccine to expand after promising preliminary data

A clinical trial at the University of Arizona Health Sciences designed to study the safety and effectiveness of a personalized cancer vaccine in combination with the immunotherapy drug Pembrolizumab will expand its cohort after promising preliminary data was presented at the annual meeting of the Society for the Immunotherapy of Cancer.

10 Nov 2020

Recommendations for initial prioritization of vaccination measures against COVID-19

The first COVID-19 vaccines could be authorized as early as the start of 2021. However, in all likelihood, there will not be sufficient vaccine doses in the beginning for all the people willing to undergo vaccination.

10 Nov 2020

New biomaterial significantly reduces scar formation following wounds

Researchers at UCLA, Duke University and other collaborating institutions have developed a biomaterial that may significantly reduce scar formation after wounding, leading to more effective skin healing.

10 Nov 2020

Exosome-mediated mRNA delivery generates broad immune response to multiple SARS-CoV-2 proteins

Recently, researchers from The Johns Hopkins University School of Medicine, Baltimore, MD, USA, and Capricor Therapeutics, Inc., Beverly Hills, CA, USA, described a new approach to SARS-CoV-2 vaccine development using exosomes to deliver mRNAs that encode the antigens from multiple structural proteins of the virus.

9 Nov 2020

Using wastewater epidemiology to monitor SARS-CoV-2 in Houston

Now, a team of researchers at Rice University, Baylor College of Medicine, and the Houston Health Department show SARS-CoV-2 RNA wastewater levels to be a strong predictive of trends in the nasal positivity rate two weeks in advance. This could help track the positivity rate for populations, speeding up the isolation and treatment of infected people.

9 Nov 2020

Wake Forest Baptist scientists use pre-clinical model to develop a safe, effective flu vaccine for infants

Newborns and young infants are particularly susceptible to the flu and are six times more likely to die from the infection than older children. Currently there is no flu vaccine available for babies less than 6 months old.

9 Nov 2020

Study suggests herd immunity to COVID-19 in New York City is low

Researchers in the United States have estimated that the proportion of people in New York City who developed antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) during the first wave of the coronavirus disease 2019 (COVID-19) pandemic is around one in eight.

9 Nov 2020

Promising yeast-expressed SARS-CoV-2 vaccine candidate effective in mice

Researchers at the Texas Children's Hospital Center for Vaccine Development, USA, have published a report on the preprint server bioRxiv that describes a yeast-expressed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) receptor-binding domain (RBD) protein, a key target of current vaccine development efforts.

9 Nov 2020

ACE2 and TMPRSS2 not the only virus-receptors to mediate SARS-CoV-2 entry

However, a recent study published on the preprint server bioRxiv in November 2020 uncovers the major role played by the N-terminal domain of the SARS-CoV-2 virus in host infection. This could be of great use in measuring the usefulness of antibodies used in convalescent plasma therapy for COVID-19.

9 Nov 2020

Immune-evading variants can emerge in SARS-CoV-2, researchers warn

An international team of researchers has shown that a mutation within severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent responsible for the coronavirus disease 2019 (COVID-19) – enables the pathogen to evade antibody-mediated immunity while maintaining replication fitness and increasing viral loads.

9 Nov 2020

‘A great day for science and humanity’; Pfizer’s COVID-19 vaccine is found to be 90% effective

Pfizer and BioNTech have today announced their new vaccine candidate (BNT162b2) is 90% effective against SARS-CoV-2.

9 Nov 2020

As faith in vaccines falters, Biden is under pressure to name new FDA chief stat

President-elect Joe Biden made COVID-19 a linchpin of his campaign, criticizing President Donald Trump's leadership on everything from masks and packed campaign rallies to vaccines.

8 Nov 2020

Researchers compare rhesus and cynomolgus macaques for SARS-CoV-2 vaccine trials

A team of researchers at the Biomedical Primate Research Centre based in the Netherlands have aimed to determine the effects of the SARS-CoV-2 pathogen on these monkeys and, subsequently, whether they make good animal models for future research in the area.

8 Nov 2020

Vaccine News and Research

Latest Vaccine News and Research

Discovery of novel hidden gene in SARS-CoV-2

Spike-based DNA vaccine shows excellent protection against SARS-CoV-2 in a hamster model

WHO Member States designate 2021 as the 'International Year of Health and Care Workers'

Five important questions about Pfizer’s COVID-19 vaccine

A promising vaccine for treating poorly immunogenic tumors

Cabotegravir highly effective in preventing HIV among women

Promising new antivirals target arboviruses and SARS-CoV-2: Nodosome inhibitors

Clinical study of personalized cancer vaccine to expand after promising preliminary data

Recommendations for initial prioritization of vaccination measures against COVID-19

New biomaterial significantly reduces scar formation following wounds

Exosome-mediated mRNA delivery generates broad immune response to multiple SARS-CoV-2 proteins

Using wastewater epidemiology to monitor SARS-CoV-2 in Houston

Wake Forest Baptist scientists use pre-clinical model to develop a safe, effective flu vaccine for infants

Study suggests herd immunity to COVID-19 in New York City is low

Promising yeast-expressed SARS-CoV-2 vaccine candidate effective in mice

ACE2 and TMPRSS2 not the only virus-receptors to mediate SARS-CoV-2 entry

Immune-evading variants can emerge in SARS-CoV-2, researchers warn

‘A great day for science and humanity’; Pfizer’s COVID-19 vaccine is found to be 90% effective

As faith in vaccines falters, Biden is under pressure to name new FDA chief stat

Researchers compare rhesus and cynomolgus macaques for SARS-CoV-2 vaccine trials

Event guide: 3rd mRNA Process Development & Manufacturing Europe eBook

How the Vutara VXL simplifies single-molecule imaging

How cohesin mechanics and nanotracker tech are redefining DNA research

Todd Bauman and Chris Povich

Vaccine News and Research

Latest Vaccine News and Research

Event guide: 3rd mRNA Process Development & Manufacturing Europe eBook

How the Vutara VXL simplifies single-molecule imaging

How cohesin mechanics and nanotracker tech are redefining DNA research

Todd Bauman and Chris Povich

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