Vaccine News and Research

Latest Vaccine News and Research

Penn Medicine launches convalescent plasma therapy trial for COVID-19 patients

Convalescent plasma therapy for COVID-19 patients -- an experimental approach of giving a transfusion of plasma collected from a donor who has recovered from COVID-19 to a patient with an active infection -- is the focus of a new two-part research initiative at Penn Medicine.

20 Apr 2020

Artificial 'candy canes' block viral entry and infection

Viruses are part of the human experience throughout our lives. They cause lots of different illnesses with the current coronavirus pandemic as just one example.

20 Apr 2020

New high-throughput approach yields libraries of probes for immunological assays

An immunological test known as a "tetramer assay" can detect T cells in a blood sample that recognize a specific antigen.

20 Apr 2020

Novel coronavirus mutation could spell trouble for vaccine development

New research shows that the novel coronavirus is undergoing mutations that could make it challenging to develop a vaccine against. There are a few vaccine candidates that are in the making to prevent COVID-19. With a potential for mutation, the vaccines that are being developed now may not work against the emergent mutated strains worry Taiwanese and Australian researchers. The study is titled, “Analysis of the mutation dynamics of SARS-CoV-2 reveals the spread history and emergence of 2 RBD mutant with lower ACE2 binding affinity.”

19 Apr 2020

Research suggests Nelfinavir and Cepharanthine as potential anti-SARS-CoV-2 agents

A new study published in the journal bioRxiv in April 2020 reports the identification of a promising multidrug treatment against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus responsible for causing COVID-19 disease. The team predicts that this combination will prevent the virus from reproducing, hence both halting the transmission and progress of the disease.

19 Apr 2020

Hydroxychloroquine and azithromycin treatment in 80 COVID-19 patients: short-term outcomes

The COVID-19 pandemic is still spreading around the world and affecting nearly 2.4 million people, with over 164,000 dead so far. With neither vaccine nor proven therapeutic drug being available so far, the need of the hour is for effective treatment. Now, a new study reports the potential usefulness of a combination of hydroxychloroquine and azithromycin as a treatment in mild cases of COVID-19 infection and urges the need for further evaluation and widespread use if its findings are confirmed.

19 Apr 2020

Computer simulations yield promising vaccine candidate against SARS-CoV-2

In a recent study that appeared on a preprint server bioRxiv, scientists from India designed a multi-epitope peptide-based vaccine that predicted high immunogenic response in the population.

19 Apr 2020

UC San Diego Health launches serological tests to detect past exposure to novel coronavirus

Clinical laboratory physicians and scientists at UC San Diego Health have launched a pair of serological tests that will look for novel coronavirus antibodies -- evidence in persons tested that they have previously been infected by SARS-CoV-2, the viral cause of COVID-19, even if they never experienced tell-tale symptoms.

18 Apr 2020

‘It’s not over until it’s over’: 5 things to know about hitting the COVID-19 peak

As New York, California and other states begin to see their numbers of new COVID-19 cases level off or even slip, it might appear as if we're nearing the end of the pandemic.

17 Apr 2020

MilliporeSigma supports Jenner Institute to reach first milestone in COVID-19 vaccine manufacturing

MilliporeSigma and The Jenner Institute today announced that The Jenner Institute has laid the foundation for large-scale production of its Covid-19 vaccine candidate, ChAdOx1 nCoV-19.

17 Apr 2020

On and off social distancing may be needed until 2022

Lockdown and social distancing measures are in place in many countries across the world, intended to stem the rapid spread of the coronavirus disease (COVID-19) global pandemic. These measures work by reducing the risk of viral transmission in communities, reducing the burden of the healthcare system in dealing with the surge of patients, overwhelming its resources and workforce. Now, experts warn that these social distancing measures may still be needed until 2022.

16 Apr 2020

Supercomputer helps find 64 compounds as potential inhibitors of the COVID-19 protease

A new study published in Chemrxiv in April 2020 describes the identification of 64 compounds that could potentially be inhibitors of replication of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that is causing the current COVID-19 disease pandemic. The research was carried out using a pharmacophore model of an essential viral enzyme, mining data from the Food and Drug Administration (FDA) database of conformations of approved drugs.

16 Apr 2020

Gold-containing drug auranofin kills 95% of SARS-CoV-2 virus in 48 hours in lab conditions

A drug called auranofin, approved for the treatment of rheumatoid arthritis, effectively inhibits severe acute respiratory syndrome coronavirus (SARS-CoV-2) in laboratory conditions, as described in a new study by Georgia State University researchers.

16 Apr 2020

Potential universal Ebola vaccine may neutralize all four harmful virus species

Infectious disease scientists report early development of a potential universal vaccine for Ebola viruses that preclinical tests show might neutralize all four species of these deadly viruses infecting people in recent outbreaks, mainly in Africa.

16 Apr 2020

Big brother wants to track your location and health data. And that’s not all bad.

A growing mix of health and technology experts are convinced that if the United States is to ever effectively track the coronavirus and slow its spread, then both self-reported and more surreptitiously gathered personal data — a mix of information about location, travel, symptoms and health conditions - must be gathered from millions of Americans.

16 Apr 2020

FDA grants Emergency Use Authorization to Ortho’s COVID-19 total antibody test

The U.S. Food and Drug Administration today announced it granted Emergency Use Authorization to Ortho Clinical Diagnostics' total antibody assay for COVID-19—the VITROS Immunodiagnostic Products Anti-SARS-CoV-2 Total Reagent Pack and Calibrators.

From Ortho-Clinical Diagnostics, Inc. 16 Apr 2020

European Commission issues guidelines on coronavirus testing methodologies

Today, as part of the European Roadmap towards lifting coronavirus containment measures, the Commission is presenting guidelines on coronavirus testing methodologies.

15 Apr 2020

Remdesivir drug stops novel coronavirus from replicating

Scientists from the University of Alberta have published findings that the antiviral drug remdesivir prevents replication of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by inhibiting RNA replication. The study, published in April 2020 in the Journal of Biological Chemistry, follows on the heels of earlier reports from the same lab in February, showing the drug's effectiveness against the related Middle East Respiratory Syndrome (MERS) virus.

15 Apr 2020

ECMO physicians outline guidance to treat critically ill COVID-19 patients

Rapidly escalating numbers of COVID-19 patients suffering from respiratory failure threaten to overwhelm hospital capacity and force healthcare providers into making challenging decisions about the care they provide.

15 Apr 2020

Health agencies urge continuation of life-saving measles vaccinations

The novel coronavirus disease, now officially called COVID-19, threatens the vaccination of millions of children across the globe. With most countries in lockdown and health care workers overwhelmed, many vaccination schedules have been delayed, threatening the welfare of infants and children.

15 Apr 2020

Vaccine News and Research

Latest Vaccine News and Research

Penn Medicine launches convalescent plasma therapy trial for COVID-19 patients

Artificial 'candy canes' block viral entry and infection

New high-throughput approach yields libraries of probes for immunological assays

Novel coronavirus mutation could spell trouble for vaccine development

Research suggests Nelfinavir and Cepharanthine as potential anti-SARS-CoV-2 agents

Hydroxychloroquine and azithromycin treatment in 80 COVID-19 patients: short-term outcomes

Computer simulations yield promising vaccine candidate against SARS-CoV-2

UC San Diego Health launches serological tests to detect past exposure to novel coronavirus

‘It’s not over until it’s over’: 5 things to know about hitting the COVID-19 peak

MilliporeSigma supports Jenner Institute to reach first milestone in COVID-19 vaccine manufacturing

On and off social distancing may be needed until 2022

Supercomputer helps find 64 compounds as potential inhibitors of the COVID-19 protease

Gold-containing drug auranofin kills 95% of SARS-CoV-2 virus in 48 hours in lab conditions

Potential universal Ebola vaccine may neutralize all four harmful virus species

Big brother wants to track your location and health data. And that’s not all bad.

FDA grants Emergency Use Authorization to Ortho’s COVID-19 total antibody test

European Commission issues guidelines on coronavirus testing methodologies

Remdesivir drug stops novel coronavirus from replicating

ECMO physicians outline guidance to treat critically ill COVID-19 patients

Health agencies urge continuation of life-saving measles vaccinations

Event guide: 3rd mRNA Process Development & Manufacturing Europe eBook

How cohesin mechanics and nanotracker tech are redefining DNA research

Todd Bauman and Chris Povich

Scaling organ‑chip technology for human‑relevant drug discovery

Vaccine News and Research

Latest Vaccine News and Research

Event guide: 3rd mRNA Process Development & Manufacturing Europe eBook

How cohesin mechanics and nanotracker tech are redefining DNA research

Todd Bauman and Chris Povich

Scaling organ‑chip technology for human‑relevant drug discovery

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