DBL Carboplatin Injection contains the active ingredient carboplatin. DBL Carboplatin
Injection is used to treat certain cancers.
2. What should I know before treatment with DBL Carboplatin Injection?
Do not use if you have ever had an allergic reaction to DBL Carboplatin Injection,
any other platinum containing medicines, mannitol or any of the ingredients listed
at the end of the CMI.
Talk to your doctor if you have any other medical conditions, take any other medicines,
or are pregnant or plan to become pregnant or are breastfeeding.
3. What if I am taking other medicines?
Some medicines may interfere with DBL Carboplatin Injection and affect how it works.
4. How is DBL Carboplatin Injection given?
DBL Carboplatin Injection is given as a single intravenous infusion (slow drip into
a vein) over 15 to 60 minutes. More instructions can be found in Section
4. How is DBL Carboplatin Injection given? in the full CMI.
5. What should I know during treatment with DBL Carboplatin Injection?
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Things you should do
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Tell your doctor straight away if you experience severe side effects.
Tell your doctor immediately if you or your partner becomes pregnant while either
of you are being treated with DBL Carboplatin injection.
Take care to minimise cuts, impacts or exposure to infection.
Remind any doctor, dentist or pharmacist who are treating you that you are being treated
with DBL Carboplatin Injection.
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Things you should not do
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Do not take any other medicines whether they require a prescription or not without
first telling your doctor or consulting with a pharmacist.
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Driving or using machines
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DBL Carboplatin Injection may cause dizziness, sight loss or problems with vision
in some people. Do not drive, operate machinery or do anything else that could be
dangerous until you know how DBL Carboplatin Injection affects you.
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Drinking alcohol
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No information is available.
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6. Are there any side effects?
Side effects of this medicine may include sore throat/mouth/tongue, mouth ulcers,
nausea, vomiting, stomach pain, diarrhoea, constipation, loss of taste, red skin rash,
itchy rash, itching, hair loss/thinning, muscle/joint pain, tiredness, pain, fever,
severe chills, infection, headache, severe flaking/peeling of the skin, yellowing
of the skin and/or eyes, fast/racing heartbeat, confusion, looking pale, dizziness,
light-headed, lack of urine/wee or blood in urine, numbness of the hands/feet, tinnitus,
roaring in the ears and hearing loss, sight loss, visual disturbances, signs of allergic
reaction (shortness of breath, wheezing or difficulty breathing; flushing; swelling
of the face/lips/tongue/other parts of the body; rash, itching/hives on the skin;
dizziness or light-headedness), unusual bruising/bleeding, shortness of breath, coughing,
difficulty breathing, chest pain, heart attack, fits/convulsions.
Active ingredient(s): carboplatin
Full Consumer Medicine Information (CMI)
This leaflet provides important information about using DBL Carboplatin Injection.
You should also speak to your doctor or pharmacist if you would like further information
or if you have any concerns or questions about using DBL Carboplatin Injection.
Where to find information in this leaflet:
1. Why am I being treated with DBL Carboplatin Injection?
DBL Carboplatin Injection contains the active ingredient carboplatin. DBL Carboplatin Injection is a medicine used to treat cancers by interfering with
DNA crosslinks in cells exposed to the drug.
DBL Carboplatin Injection is used to treat the following cancers/tumours
epithelial ovarian cancer
small cell lung cancer
cancer of the head and neck
cancer of the testis
children's brain tumours
cancer of soft tissue
neuroblastoma
2. What should I know before treatment with DBL Carboplatin Injection?
Warnings
Do not use DBL Carboplatin Injection if:
you are allergic to carboplatin, other platinum-containing compounds (e.g., cisplatin),
or mannitol, or any of the ingredients listed at the end of this leaflet.
have severe bone marrow depression (have a problem with the production of blood cells
and platelets)
have severe problems with your kidneys
have severe bleeding
are pregnant and breastfeeding
If you are not sure of any of the above, ask your doctor.
Some of the symptoms of an allergic reaction may include rash, itchy rash, redness
of the skin, itching, difficulty in breathing and dizziness or feeling faint.
Check with your doctor if you:
have problems with your kidneys
have had or are planning to have any vaccinations
have herpes zoster, existing or recent chicken pox, or recent exposure to chicken
pox
plan to have any dental treatment
are having other treatment that uses equipment including needles, syringes, catheters
During treatment, you may be at risk of developing certain side effects. It is important
you understand these risks and how to monitor for them. See additional information
under Section
6. Are there any side effects?
Pregnancy and breastfeeding
Check with your doctor if you are pregnant or intend to become pregnant.
DBL Carboplatin Injection is potentially harmful to the fetus.
Women should use effective contraception during treatment with DBL Carboplatin Injection
and for at least 7 months after treatment.
Talk to your doctor if you are breastfeeding or intend to breastfeed. Breastfeeding
should be discontinued while being treated with DBL Carboplatin Injection and for
at least 1 month after treatment.
DBL Cisplatin Injection may affect female fertility. Check with your doctor for advice
on fertility preservation before you begin treatment.
Males
If you are with a female partner who can become pregnant, you should use a reliable
method of contraception during treatment with DBL Cisplatin Injection and for at least
4 months after treatment.
DBL Cisplatin Injection may affect male fertility. Check with your doctor for advice
on fertility preservation before you begin treatment.
Use in the elderly
There may be a greater chance of numbness or weakness of the arms and legs if you
are over 65years of age.
Use in children
There may be a chance of delayed onset of loss of hearing in children treated with
DBL Carboplatin Injection. Hearing tests during treatment and longer term after finishing
treatment are recommended.
3. What if I am taking other medicines?
Tell your doctor, nurse or pharmacist if you are taking any other medicines, including
any medicines, vitamins or supplements that you buy without a prescription from your
pharmacy, supermarket or health food shop.
Some medicines may interfere with DBL Carboplatin Injection, these include:
some medicines used to treat infections, including gentamicin, tobramycin, amikacin
and neomycin
other medicines used to treat cancer including cisplatin, paclitaxel and cyclophosphamide
some vaccines
phenytoin, a medicine used to treat seizures
Check with your doctor, nurse or pharmacist if you are not sure about what medicines,
vitamins or supplements you are taking and if these affect DBL Carboplatin Injection.
4. How is DBL Carboplatin Injection given?
How much is given
Your doctor will decide how much DBL Carboplatin Injection you should receive and
the length of time for which you should receive it. This will depend on your condition
and other factors, such as your weight.
How is DBL Carboplatin Injection given
DBL Carboplatin Injection is given as a single intravenous infusion (as a slow drip
into a vein) over 15 to 60 minutes.
If you use too much DBL Carboplatin Injection
As DBL Carboplatin Injection is given under the close supervision of your doctor,
it is very unlikely that you will receive too much. If you experience any side effects,
tell your doctor or nurse immediately.
5. What should I know during treatment with DBL Carboplatin Injection?
Things you should do
Keep all of your doctor’s appointments and attend any tests as directed, as treatment
with DBL Carboplatin Injection requires your doctor to monitor your kidneys and blood.
Treatment with DBL Carboplatin Injection can lower the number of white blood cells
and platelets in your blood. This means that you have an increased chance of getting
an infection or bleeding.
The following precautions should be taken to reduce your risk of infection or bleeding:
avoid people who have infections. Check with your doctor immediately if you think
you may be getting an infection, or if you get a fever, chills, cough, hoarse throat,
lower back or side pain or find it painful or difficult to urinate.
wash your hands frequently with soap and water, especially before eating, after using
the bathroom, and after touching high-touch surfaces.
be careful when using a toothbrush, toothpick or dental floss. Your doctor, dentist,
nurse or pharmacist may recommend other ways to clean your teeth and gums. Check with
your doctor before having any dental work.
be careful not to cut yourself when you are using sharp objects such as a razor or
nail cutters.
avoid contact sports or other situations where you may bruise or get injured..
Tell your doctor straight away if you:
have a rash, itchy rash, redness of the skin, itching, difficulty in breathing and
dizziness or feeling faint
have tingling or numbness of the hands or feet, or any hearing loss or changes to
your hearing
have fits or convulsions, headache, confusion, blindness or other visual disturbances
have tiredness, headaches, being short of breath when exercising, dizziness, looking
pale and yellowing of the skin and/or eyes
unusual bruising or bleeding, decreased urinating or blood in the urine or swelling
severe vomiting or severe diarrhoea
Remind any doctor, nurse, dentist or pharmacist who are treating you that you are
being treated with DBL Carboplatin Injection.
Things you should not do
Do not take any other medicines whether they require a prescription or not without
first telling your doctor or consulting a pharmacist.
Driving or using machines
Be careful before you drive or use any machines or tools until you know how DBL Carboplatin
Injection affects you.
DBL Carboplatin Injection may cause dizziness and problems with vision in some people
Drinking alcohol
No information is available.
Looking after your medicine
DBL Carboplatin Injection is stored in the pharmacy or on the hospital ward under
the correct conditions.
Disposal of DBL Carboplatin Injection
The hospital staff will correctly dispose of any DBL Carboplatin Injection.
6. Are there any side effects?
All medicines can have side effects. Some side effects may need medical attention.
See the information below and, if you need to, ask your doctor or nurse if you have
any further questions about side effects.
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Side effects
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What to do
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mouth ulcers
nausea, vomiting
stomach pain
diarrhoea, constipation
loss of taste
red skin rash, itchy rash, itching
hair loss or thinning
muscle and joint pain
tiredness
pain
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Speak to your doctor if you have any of these side effects and they worry you.
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fever, severe chills
sore throat
infection
headache
severe flaking or peeling of the skin
yellowing of the skin and/or eyes
fast/racing heartbeat
confusion
looking pale
dizziness, light-headed
lack of urine/wee or blood in urine
numbness of the hands or feet
tinnitus, roaring in the ears and hearing loss
sight loss, visual disturbances
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Speak to your doctor as soon as possible if you notice any of these side effects.
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signs of an allergic reaction such as shortness of breath, wheezing or difficulty
breathing; flushing; swelling of the face, lips, tongue or other parts of the body;
rash, itching or hives on the skin; dizziness or light-headedness
unusual bruising or bleeding
severe vomiting
severe diarrhoea
shortness of breath, coughing, difficulty breathing
chest pain, heart attack
fits/convulsions
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Call your doctor straight away, or go straight to the Emergency Department at your
nearest hospital if you notice any of these serious side effects.
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Tell your doctor or pharmacist if you notice anything else that may be making you
feel unwell.
Other side effects not listed here may occur in some people.
Some of these side effects (for example certain liver conditions, and blood abnormalities)
can only be found when your doctor does tests from time to time to check your progress.
Reporting side effects
After you have received medical advice for any side effects you experience, you can
report side effects to the Therapeutic Goods Administration online at
www.tga.gov.au/reporting-problems . By reporting side effects, you can help provide more information on the safety of
this medicine.
Always make sure you speak to your doctor or pharmacist before you decide to stop
taking any of your medicines.
7. Product details
This medicine is only available with a doctor's prescription.
What DBL Carboplatin Injection contains
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Active ingredient
(main ingredient)
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carboplatin
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Other ingredients
(inactive ingredients)
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water for injections
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Do not take this medicine if you are allergic to any of these ingredients.
Each DBL Carboplatin Injection carboplatin 10 mg.
What DBL Carboplatin Injection looks like
DBL Carboplatin Injection is a clear, colourless or slightly yellow solution in vials.
Aust R 46845, 46846, 12880
Who distributes DBL Carboplatin Injection
Pfizer Australia Pty Ltd
Sydney NSW
This leaflet was prepared in October 2025.