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SickKids scientists shine light on the complex genetics that underlie blood pressure regulation

Scientists at The Hospital for Sick Children (SickKids) are delving deep into the non-coding genome to unravel the complex genetics that underlie blood pressure regulation and hypertension (high blood pressure) – the leading cause of cardiovascular disease affecting 1.25 billion people worldwide.

6 Jun 2023

COLOTECT 1.0 receives market authorization from Malaysia's Medical Device Authority

Recently, BGI Genomics' COLOTECT 1.0 DNA Methylation Detection Kit for Human SDC2, ADHFE1, and PPP2R5C Genes (Real-Time PCR), Sample Pretreatment Kit for Methylation Detection, DNA Isolation Kit, Stool Sample Collection Kit have received market authorization from Malaysia's Medical Device Authority (hereinafter referred to as MDA).

6 Jun 2023

Breakthrough: Sequencing functional antibody proteins directly from human blood

Rapid Novor Inc., the world’s leader in mass spectrometry (MS)-based antibody protein sequencing, announced today that its REpAb® antibody discovery platform was used to successfully sequence a complex mixture of functional antibodies directly from the serum of a human patient after receiving a COVID-19 vaccine.

6 Jun 2023

ELRIG UK Announces Prof Janet Hemingway and Dr Dave Powell as Keynote Speakers at Drug Discovery 2023

ELRIG Drug Discovery 2023 at ACC Liverpool (18–19 October) to focus on diverse thinking and new perspectives.

From ELRIG (UK) Ltd. 6 Jun 2023

Fine-tuning cell mechanics stimulates hair growth: Study

Just as people's joints can get stiff as they age and make it harder for them to move around, hair follicle stem cells also get stiff, making it harder for them to grow hair, reports a new Northwestern Medicine study.

6 Jun 2023

ISSCR proposes new guidelines for using stem cells in research

The International Society for Stem Cell Research (ISSCR) today released the ISSCR Standards for Human Stem Cell Use in Research, an international collaboration aimed at enhancing rigor in preclinical research and ultimately strengthening the pipeline of therapies for patients.

6 Jun 2023

Efficient machine learning pipeline predicts the location of nanoscale interactions

Identifying whether and how a nanoparticle and protein will bind with one another is an important step toward being able to design antibiotics and antivirals on demand, and a computer model developed at the University of Michigan can do it.

6 Jun 2023

How lipid metabolites in the gut aid in regulatory T-cell differentiation

Researchers describe the Treg-cell-inducing activity of lipid extracts from the feces of specific-pathogen-free mice.

6 Jun 2023

Large-scale comprehensive sequencing helps downstream medical care in newborns

Researchers who lead the world's first comprehensive sequencing program for newborn infants have published the next chapter in the ongoing study of the BabySeq Project, with new findings on infants and families who have been followed for 3-5 years.

6 Jun 2023

New pangenome reference could deepen our understanding of human biology and disease

The first human genome, which has served as the reference until now, was released approximately 20 years ago.

5 Jun 2023

CRISPR/Cas9 identifies a gene critical to stony corals' ability to build their skeletons

New work led by Carnegie's Phillip Cleves uses cutting-edge CRISPR/Cas9 genome editing tools to reveal a gene that's critical to stony corals' ability to build their reef architectures.

5 Jun 2023

Study improves the genetic knowledge of human eyebrow appearance

The first gene mapping study on eyebrow thickness in Europeans discovered three previously unreported genetic loci, as reported in a Letter to the Editor in the Journal of Investigative Dermatology, published by Elsevier.

5 Jun 2023

New antibiotic-resistance genes are present in bacteria in almost all environments, study shows

Genes that make bacteria resistant to antibiotics are much more widespread in our environment than was previously realised.

5 Jun 2023

Freiburg researchers gain new insights into metabolic processes in the kidney

Researchers at the Faculty of Medicine at the University of Freiburg have gained significant new insights into metabolic processes in the kidney.

5 Jun 2023

Study provides a treasure trove of information on molecular biology of the immune system

Researchers at Sanford Burnham Prebys, collaborating with scientists from Eli Lilly and Company, have revealed the structure and function of a drug called LY3361237, which can reduce the harmful activity of the immune system to help treat autoimmune diseases.

5 Jun 2023

Research sheds new light on the genetic architecture of bipolar disorder

Bipolar disorder (BD) is a major psychiatric condition that afflicts about 1% of people. Symptoms of BD include sudden onset of depressive mood with loss of interest which alternates with a manic state of hyperactivity.

5 Jun 2023

New research reveals the genetic diversity and evolutionary history of primates

The rich genetic diversity and evolutionary history of primates – the group that includes monkeys, apes, lemurs and humans ourselves - has been revealed in full for the first time in a new research paper published today.

5 Jun 2023

Innovative probe could deepen the understanding of key cellular messenger and lead to new drug discoveries

A ground-breaking study by Loughborough University and the University of Oxford has led to the development of a small molecule probe that could deepen our understanding of a crucial cellular messenger and lead to the development of new therapeutic drugs.

5 Jun 2023

Groundbreaking study maps molecular architecture of the visual system's integral components

A groundbreaking study has taken a significant step towards understanding the complexities of the human eye.

4 Jun 2023

Cross-country culinary microbes: Uncovering a shared kitchen microbiota across European homes

Microbial diversity in residential kitchens across five European countries was examined, revealing common bacterial genera/families and their distribution on cleaning utensils and kitchen surfaces. The study highlights variations in microbial composition by country, object type, and cleaning utensil material.

4 Jun 2023

Life Science News

SickKids scientists shine light on the complex genetics that underlie blood pressure regulation

COLOTECT 1.0 receives market authorization from Malaysia's Medical Device Authority

Breakthrough: Sequencing functional antibody proteins directly from human blood

ELRIG UK Announces Prof Janet Hemingway and Dr Dave Powell as Keynote Speakers at Drug Discovery 2023

Fine-tuning cell mechanics stimulates hair growth: Study

ISSCR proposes new guidelines for using stem cells in research

Efficient machine learning pipeline predicts the location of nanoscale interactions

How lipid metabolites in the gut aid in regulatory T-cell differentiation

Large-scale comprehensive sequencing helps downstream medical care in newborns

New pangenome reference could deepen our understanding of human biology and disease

CRISPR/Cas9 identifies a gene critical to stony corals' ability to build their skeletons

Study improves the genetic knowledge of human eyebrow appearance

New antibiotic-resistance genes are present in bacteria in almost all environments, study shows

Freiburg researchers gain new insights into metabolic processes in the kidney

Study provides a treasure trove of information on molecular biology of the immune system

Research sheds new light on the genetic architecture of bipolar disorder

New research reveals the genetic diversity and evolutionary history of primates

Innovative probe could deepen the understanding of key cellular messenger and lead to new drug discoveries

Groundbreaking study maps molecular architecture of the visual system's integral components

Cross-country culinary microbes: Uncovering a shared kitchen microbiota across European homes

Edoardo Fabini

Reducing polypharmacy through innovative drug formulation technologies

How innovation in dried blood spot testing is transforming neurological disease monitoring

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