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Revolutionizing protein design: AI generates novel sequences

Researchers present two deep-learning models that can predict amino acid sequences and 3D protein structures based on secondary-structure design objectives. These models offer de novo design capacity and can discover new protein sequences beyond known proteins.

25 Apr 2023

Previously unknown mechanisms may lead to new approaches to fight viral infections

Viruses like influenza A and Ebola invade human cells in a number of steps. In an interdisciplinary approach, research teams from Heidelberg University and Heidelberg University Hospital investigated the final stages of viral penetration using electron tomography and computer simulations.

25 Apr 2023

Highly activatable Raman probes detect multiple enzyme activities in heterogeneous biological tissues

Raman imaging offers a greater potential for detecting multiple enzyme activities than fluorescence imaging, demonstrate Tokyo Tech researchers by developing 9CN-rhodol-based activatable Raman probes using a novel mechanism for Raman signal activation.

25 Apr 2023

T cell-mediated recognition of conserved bacterial epitope generates broad immunity

Typically T cells of the immune system respond to a specific feature (antigen) of a microbe, thereby generating protective immunity.

25 Apr 2023

A new platform for testing cancer drug toxicity

For people with cancer, chemotherapy saves lives, but for some patients, the treatment comes with a side effect—heart damage.

25 Apr 2023

Study establishes a new method for examining relationships between neuron type and function

Investigators at Cedars-Sinai have created computer-generated models to bridge the gap between "test tube" data about neurons and the function of those cells in the living brain.

25 Apr 2023

INTEGRA Biosciences’ new eBook: all you need to know about ELISAs

INTEGRA Biosciences is pleased to announce the release of a new eBook providing a complete guide to ELISAs.

From INTEGRA Biosciences 25 Apr 2023

The Wonder of DNA: Reflections from Dr. Francis Collins on the 20th Anniversary of the Human Genome Project

To highlight how far the field of genetics has come, we spoke with Dr. Francis Collins, the leader of the Human Genome Project about his incredible career in genetics.

25 Apr 2023

Bee venom nanoparticles: Buzzworthy breakthrough in battling antibiotic-resistant bacteria

Study aimed to test the antibacterial and cytotoxic effects of bee venom-loaded chitosan nanoparticles (BV-loaded CS-NPs) against Staphylococcus aureus. The results showed that BV-loaded CS-NPs had enhanced antibacterial activity and minimal cytotoxicity, making it a promising antibiotic alternative.

24 Apr 2023

A rapid and affordable in vitro model to test SARS-CoV-2 susceptibility in animal species

Research investigates the susceptibility of seven bat species to SARS-CoV-2 by expressing their ACE2 receptor in a non-permissive avian cell line. The study found that all seven bat species were susceptible to SARS-CoV-2, but the level of virus replication differed between bat species and virus variants.

24 Apr 2023

New and efficient technique for rapid antibiotic susceptibility testing using optical microscopy

Researchers at EPFL and Vrije Universiteit Brussel have developed a novel and highly efficient method for rapid antibiotic susceptibility testing using optical microscopy.

24 Apr 2023

Exploring metabolic compatibility as a possible limiting factor to prokayrotic endosymbioses

"One of the great mysteries of biology," says Eric Libby, former SFI Postdoctoral Fellow, now an associate professor at the Integrated Science Lab (IceLab), Umeå University in Sweden, "is eukaryogenesis, or how eukaryotes arose." Scientists consider this to be a period of major evolutionary transition, critical to our understanding of the history and evolution of life on Earth.

24 Apr 2023

Researchers pioneer a new method for fast miRNA amplification and detection

In the early 1990s, scientists who were studying the development of a roundworm identified a small RNA molecule that regulated the expression of specific genes.

24 Apr 2023

New computational method identifies routes of cellular differentiation in acute myeloid leukemia

Researchers have developed a new method to distinguish between cancerous and healthy stem cells and progenitor cells from samples of patients with acute myeloid leukemia (AML), a disease driven by malignant blood stem cells that have historically been difficult to identify.

24 Apr 2023

New genome editing technology achieves efficient and precise large DNA insertions

GAO Caixia's group from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences has developed a new genome editing technology that achieves efficient and precise targeted insertion of large DNA segments in plants.

24 Apr 2023

Repair crews may move in to help fix the oxidative damage in protein factories

In a discovery fundamental to the inner workings of cells, scientists have discovered that if oxidative stress damages protein factories called ribosomes, repair crews may move in to help fix the damage so work can quickly resume.

24 Apr 2023

Bioengineered drug candidate can counter S. aureus infection in early tests

Researchers at NYU Grossman School of Medicine and Janssen Biotech, Inc. have shown in early tests that a bioengineered drug candidate can counter infection with Staphylococcus aureus – a bacterial species widely resistant to antibiotics and a major cause of death in hospitalized patients.

24 Apr 2023

Life Science News

Revolutionizing protein design: AI generates novel sequences

Previously unknown mechanisms may lead to new approaches to fight viral infections

Highly activatable Raman probes detect multiple enzyme activities in heterogeneous biological tissues

T cell-mediated recognition of conserved bacterial epitope generates broad immunity

A new platform for testing cancer drug toxicity

Study establishes a new method for examining relationships between neuron type and function

INTEGRA Biosciences’ new eBook: all you need to know about ELISAs

The Wonder of DNA: Reflections from Dr. Francis Collins on the 20th Anniversary of the Human Genome Project

Bee venom nanoparticles: Buzzworthy breakthrough in battling antibiotic-resistant bacteria

A rapid and affordable in vitro model to test SARS-CoV-2 susceptibility in animal species

New and efficient technique for rapid antibiotic susceptibility testing using optical microscopy

Exploring metabolic compatibility as a possible limiting factor to prokayrotic endosymbioses

Researchers pioneer a new method for fast miRNA amplification and detection

New computational method identifies routes of cellular differentiation in acute myeloid leukemia

New genome editing technology achieves efficient and precise large DNA insertions

Repair crews may move in to help fix the oxidative damage in protein factories

Bioengineered drug candidate can counter S. aureus infection in early tests

ESPG AG reviews options for refinancing the corporate bond 2018/2023 and mandates Quirin Privatbank AG

Study reveals CMPK-2 protein-coding gene as a potent inhibitor of flaviviruses

Researchers develop a backpack-based myeloid cell therapy for MS patients

Transforming Lab Workflows with Cell Culture Automation

Building Bridges to Scalable Allogeneic Cell Therapy

Edoardo Fabini

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