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Understanding the prevalence and dissemination aminoglycoside resistance genes

Choosing the appropriate antibiotics to treat bacterial infections has grown more challenging because of the emergence of antibiotic-resistant bacteria.

17 Apr 2023

How SARS-CoV-2 Omicron subvariants have evolved to evade host T-cell immunity

Researchers investigate whether SARS-CoV-2 and its variants have evolved to evade CD8+ T cell-mediated immunity.

15 Apr 2023

Study uncovers a novel fold within the SARS-CoV-2 replication co-factor non-structural protein 9

Researchers present the crystal structure of an anti-non-structural protein 9 specific nanobody in complex with the SARS-CoV-2 nsp9.

15 Apr 2023

First-ever largest atlas of post-zygotic genome mutations in healthy human tissue created

Researchers have created the largest atlas of post-zygotic genome mutations in healthy human tissue ever assembled - a scientific advancement that could unlock new avenues for diagnosing and treating genetic disease.

13 Apr 2023

B cells use mechanical force to pull antigen molecules off other cells

Most cells evolve slowly, accumulating incremental changes that better suit their environments. Immune cells, because they must adapt rapidly to counter new threats, evolve much more quickly.

13 Apr 2023

New clinical RNA sequencing platform helps carve a path for Precision Child Health

A new clinical RNA sequencing platform at The Hospital for Sick Children (SickKids) is helping to facilitate research into rare genetic conditions and carve a path for Precision Child Health, a movement at SickKids to deliver individualized care for every patient.

13 Apr 2023

Study uncovers hallmarks to improving pancreatic cancer therapy

Scientists from the University of California, Irvine, the University of Michigan and the University of Texas MD Anderson Cancer Center have made a significant contribution to the field of pancreatic cancer research.

13 Apr 2023

Researchers show how the EBV virus exploits genomic weaknesses to cause cancer

The Epstein-Barr virus (EBV) is easily spread through bodily fluids, primarily saliva, such as kissing, shared drinks or using the same eating utensils.

13 Apr 2023

Curtin researchers identify the genetic signature of pre-malignant liver cells

Researchers at Curtin University have identified the genetic signature of pre-malignant liver cells, offering potentially significant implications for the almost 3,000 Australians diagnosed with the deadly cancer each year.

13 Apr 2023

Genomic study reveals Babesia duncani's pathogenicity and virulence

'Tis the season for hiking now that spring has arrived and temperatures are on the upswing. But with hikes come insect bites and on the increase in North America is babesiosis, a malaria-like disease spread especially between May and October by a tick.

13 Apr 2023

Changes to tumor DNA can help predict cancer's next move

Knowing whether a tumor might grow or spread to other parts of a patient’s body could be key to survival – and now scientists are one step closer to unlocking the ability to predict just that.

13 Apr 2023

Research reveals molecular features of rare mtDNA mutations

A high-throughput single-cell single-mitochondrial genome sequencing technology known as iMiGseq has provided new insights into mutations of mitochondrial DNA (mtDNA) and offers a platform for assessing mtDNA editing strategies and genetic diagnosis of embryos prior to their implantation.

13 Apr 2023

New tool provides insight into the developmental history of certain immune cells

A new tool that can uncover the developmental history of certain immune cells is now freely available worldwide. The tool provides insights into the stages that immune cells go through in a healthy individual and how this can be impacted in disease.

13 Apr 2023

Award-winning project uses INTEGRA pipettes for success in international genetic engineering competition

Students from the University of Groningen, Netherlands, enjoyed gold medal success at last year’s iGEM competition.

From INTEGRA Biosciences 13 Apr 2023

From Sanger Sequencing to the Human Genome Project: The Evolution of DNA Sequencing Technology

In this inspiring interview, we speak to Dr. Radoje Drmanac, co-founder of Complete Genomics, about the past, present, and future of genomics research.

From MGI 13 Apr 2023

The virological characteristics of XBB.1.16

Researchers perform extensive multiscale investigations to explore virological characteristics of the SARS-CoV-2 Omicron XBB subvariant, XBB.1.16.

12 Apr 2023

Researchers discover important drug target for preventing blood cancer

An international coalition of biomedical researchers co-led by Alexander Bick, MD, PhD, at Vanderbilt University Medical Center has determined a new way to measure the growth rate of precancerous clones of blood stem cells that one day could help doctors lower their patients' risk of blood cancer.

12 Apr 2023