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New lab method accelerates diagnosis of genetic disorders of the immune system

A new laboratory method developed by researchers at Columbia University Vagelos College of Physicians and Surgeons may now help physicians more quickly diagnose patients with suspected genetic disorders of the immune system, many who have been trapped in diagnostic limbo for years.

20 Jun 2025

Researchers find unique genetic profile in childhood cancer survivors with cardiomyopathy

Scientists at St. Jude Children’s Research Hospital studied how common and rare genetic variants influence late-onset cardiomyopathy risk, highlighting the unique genetic complexity of childhood cancer survivors.

20 Jun 2025

Histone modification involved in chromosome and spindle stabilization in mouse oocytes

The accurate distribution of chromosomes in an oocyte is essential for the correct transmission of genetic information to the next generation.

20 Jun 2025

Discovery of key protein reveals why exercise strengthens muscles and bones

"Exercise is good for your health" is a well-known phrase, but few people can clearly explain how and why it benefits the human body."

20 Jun 2025

Chinese scientists develop highly efficient process for beta-blocker production

Chinese scientists have developed a breakthrough process that significantly improves the efficiency and environmental friendliness of beta-blocker production-with a focus on the widely used compound propranolol, which plays a vital role in managing cardiovascular conditions such as hypertension, arrhythmia, and angina.

20 Jun 2025

Transfer RNA-derived small RNAs transform the landscape of liquid biopsy

A new review highlights the transformative potential of transfer RNA-derived small RNAs (tsRNAs) in the field of liquid biopsy, emphasizing their role as promising biomarkers for a wide range of diseases, particularly cancers.

20 Jun 2025

Fibroblast Growth Factor 8 drives key processes in embryonic development

The role of Fibroblast Growth Factor 8 (FGF8) in embryonic development and organ formation is gaining increased recognition as scientists uncover its wide-ranging influence.

20 Jun 2025

New 3D immunohistochemistry method enhances deep tissue imaging

Three dimensional immunohistochemistry (3D-IHC) has transformed our ability to visualize the spatial arrangement of cells and molecules in intact tissues.

19 Jun 2025

Herpes virus reshapes the human genome's architecture to aid its replication

Viruses are entirely dependent on their hosts to reproduce. They ransack living cells for parts and energy and hijack the host's cellular machinery to make new copies of themselves.

19 Jun 2025

Pandorabactins help pathogenic bacteria compete for iron in the lungs

An interdisciplinary research team led by the Leibniz-HKI in Jena has discovered a new group of bioactive natural compounds in pathogenic bacteria of the genus Pandoraea: pandorabactins.

19 Jun 2025

New 3D model reveals how nose stem cells support sense of smell

Using a newly devised, three-dimensional model to study the regeneration of nerve tissue in the nose, researchers at Tufts University School of Medicine and the Graduate School of Biomedical Sciences (GSBS) and colleagues have discovered that one type of stem cell thought to be dormant may play a more significant role in preserving the sense of smell than originally believed.

19 Jun 2025

Scientists find hundreds of genes that behave like light switches

Gene expression, where cells use the genetic information encoded in DNA to produce proteins, has been thought of as a dimmer light.

19 Jun 2025

Full tumor DNA sequencing becomes standard for children with cancer

Readouts of the full DNA of children with cancer at diagnosis have been implemented as the standard of care in a European first.

19 Jun 2025

Early infant behavior predicts cognitive ability decades later

Watching a baby babble, play and interact with others can provide useful insight into what their cognitive ability might be like decades later, according to new University of Colorado Boulder research published in the journal PNAS.

19 Jun 2025

C-Path’s TRxA awards $250,000 grant to develop novel treatment for type 1 diabetes

Critical Path Institute's (C-Path) Translational Therapeutics Accelerator (TRxA) proudly announced today a $250,000 grant award aimed at developing a novel treatment for type 1 diabetes (T1D).

19 Jun 2025

Utah State biologist investigates chromosomal changes driving evolution

How do living things evolve? What is the myriad of processes by which generic variations in a population affect organisms' survival and allow reproduction in an ever-changing environment?

19 Jun 2025

Fruit fly study reveals how muscle cells sculpt organs

A new study from scientists at the University of North Carolina at Chapel Hill reveals that the cells shaping our organs may be far more mobile and coordinated than once believed.

19 Jun 2025

Kupffer cell reprogramming in embryos explains metabolic disorders in offspring

Children born to obese mothers are at higher risk of developing metabolic disorders, even if they follow a healthy diet themselves.

18 Jun 2025

New insights into how inhalational anesthetics induce general anesthesia

Since their anesthetic effects were discovered approximately 180 years ago, inhalational anesthetics have been used for general anesthesia in surgical operations.

18 Jun 2025

New molecular atlas offers unprecedented insight into human kidney function

The kidney, a critical organ for waste filtration and fluid regulation, is the subject of a groundbreaking molecular mapping project that could reshape our understanding of renal health.

18 Jun 2025