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Study investigates the effects of calycosin on breast cancer cell progression

Aging-US published "Calycosin inhibits breast cancer cell migration and invasion by suppressing EMT via BATF/TGF-β1" which reported that in this study, the authors investigated the effects of calycosin on breast cancer cell progression and their underlying mechanisms. Calycosin dose- and time-dependently inhibited proliferation, migration, and invasion by T47D and MCF-7 breast cancer cells by downregulating basic leucine zipper ATF-like transcription factor expression.

23 Aug 2021

Study provides a detailed picture of oil refining capacity and global CO2 emissions

A global inventory has revealed that CO2 emissions from oil refineries were 1.3 Gigatonnes (Gt) in 2018 and could be as large as 16.5 Gt from 2020 to 2030.

23 Aug 2021

Improving widely-adopted thermal vulnerability indices to mitigate the effects of climate change

It is not easy to predict how animals – from insects to fish – are going to respond to climate change and especially extremes of temperature. This lack of understanding hinders our ability to predict the vulnerability of these animals to climate change.

23 Aug 2021

Analysis of seadragon genome offers new insights into its phenotype and sex-determination locus

A study by Prof. LIN Qiang from the South China Sea Institute of Oceanology (SCSIO) of the Chinese Academy of Sciences and his collaborators from Singapore and Germany lifts the veil on seadragons' mysterious looks, and sheds light on a sex-determination locus shared by seadragons and alligator pipefish, both members of the Syngnathidae family.

22 Aug 2021

Stress signal from fat cells could help protect the heart from obesity’s negative consequences

A stress signal received by the heart from fat could help protect against cardiac damage induced by obesity, a new study led by UT Southwestern researchers suggests.

20 Aug 2021

Rice University awarded $4 million CPRIT grant to establish Genetic Design and Engineering Center

Rice University faculty members led by bioengineer Gang Bao have been awarded a $4 million grant by the Cancer Prevention and Research Institute of Texas to establish the Genetic Design and Engineering Center.

20 Aug 2021

Heidelberg researchers focus on developing drugs against flavi- and coronaviruses

New drugs are intended to help stop viral zoonoses - infections that jump from animals to humans. To study suitable inhibitors, Prof. Dr Christian Klein from the Institute of Pharmacy and Molecular Biotechnology of Heidelberg University is receiving funding in the amount of 450,000 euros from the Volkswagen Foundation.

20 Aug 2021

Researchers develop an integrative approach to boost accuracy of mosquito vector surveillance

A team of researchers from the National University of Singapore, led by Assistant Professor Nalini Puniamoorthy from the Department of Biological Sciences, has developed an integrative approach that increases the accuracy of mosquito surveillance and management.

20 Aug 2021

Researchers create a novel strategy for developing an effective TB vaccine

Innovators at Purdue University and Houston Methodist Research Institute have created a novel strategy for developing an effective vaccine for a widespread form of tuberculosis.

20 Aug 2021

Northwestern scientists discover remarkable longevity in a subset of mitochondrial proteins

Northwestern Medicine investigators have discovered that a subset of proteins in mitochondria of brain and heart cells are long-lived, supporting the long-term stability of mitochondrial complex architecture.

20 Aug 2021

Regular physical exercise modulates iron metabolism in Alzheimer’s mouse model

A recent experimental study shows how regular physical exercise modulates iron metabolism in both the brain and the muscles.

20 Aug 2021

New analytical method visualizes cell functions in vasculature-on-a-chip

A microphysiological system (MPS), also known as an organ-on-a-chip, is a 3D organ construct using human cells that help reveal how organs respond to drugs and environmental stimuli.

20 Aug 2021

SARS-CoV-2 mutations alter dynamics of neutralizing antibodies

A new study describes how monoclonal antibodies raised against SARS-CoV-2 are affected by mutations in the antibody binding site.

20 Aug 2021

SARS-CoV-2 lambda variant escapes immune response via spike mutations

A new study explores the mechanism by which the SARS-CoV-2 lambda variant has acquired immune evasion capabilities above that of the wildtype.

20 Aug 2021

Researchers identify key protein that plays an essential role in male fertility

Mammalian sperm cannot fertilize an egg from the get-go. It's an ability acquired only after insemination, during passage through the female reproductive tract, and requires two consecutive, time-sensitive processes to provide sperm with the physical and biochemical traits necessary to complete their fundamental job.

20 Aug 2021

Researchers identify genes associated with biochemical recurrence in prostate adenocarcinoma

Aging-US published "Identification of microenvironment related potential biomarkers of biochemical recurrence at 3 years after prostatectomy in prostate adenocarcinoma" which reported that the authors aimed to identify the potential prognostic genes in the prostate adenocarcinoma microenvironment and to estimate the causal effects simultaneously.

20 Aug 2021

New insights into opportunities and challenges of macrogenetics

The burgeoning field of macrogenetics is the focus of a new review published in Nature Reviews Genetics by a global, multidisciplinary team of researchers seeking to better answer fundamental biodiversity questions.

20 Aug 2021

New mouse line reveals the state of protein balance in the mammalian brain for the first time

Proteins are the "tools" of our cells – they are essential to all vital tasks. However, they are only able to do their jobs if they fold correctly and adopt their respective, very specific 3D structure.

20 Aug 2021

Study: PirB inhibits the self-renewal and differentiation capacities of neural stem cells

Aging-US published "PirB functions as an intrinsic suppressor in hippocampal neural stem cells" which reported that neural stem cells play pivotal roles during prenatal development and throughout life.

20 Aug 2021

Human waste-derived nutrient can help sustain agriculture, economies

The future connection between human waste, sanitation technology and sustainable agriculture is becoming more evident. According to research directed by University of Illinois Urbana-Champaign civil and environmental engineering professor Jeremy Guest, countries could be moving closer to using human waste as fertilizer, closing the loop to more circular, sustainable economies.

20 Aug 2021

Life Science News

Study investigates the effects of calycosin on breast cancer cell progression

Study provides a detailed picture of oil refining capacity and global CO2 emissions

Improving widely-adopted thermal vulnerability indices to mitigate the effects of climate change

Analysis of seadragon genome offers new insights into its phenotype and sex-determination locus

Stress signal from fat cells could help protect the heart from obesity’s negative consequences

Rice University awarded $4 million CPRIT grant to establish Genetic Design and Engineering Center

Heidelberg researchers focus on developing drugs against flavi- and coronaviruses

Researchers develop an integrative approach to boost accuracy of mosquito vector surveillance

Researchers create a novel strategy for developing an effective TB vaccine

Northwestern scientists discover remarkable longevity in a subset of mitochondrial proteins

Regular physical exercise modulates iron metabolism in Alzheimer’s mouse model

New analytical method visualizes cell functions in vasculature-on-a-chip

SARS-CoV-2 mutations alter dynamics of neutralizing antibodies

SARS-CoV-2 lambda variant escapes immune response via spike mutations

Researchers identify key protein that plays an essential role in male fertility

Researchers identify genes associated with biochemical recurrence in prostate adenocarcinoma

New insights into opportunities and challenges of macrogenetics

New mouse line reveals the state of protein balance in the mammalian brain for the first time

Study: PirB inhibits the self-renewal and differentiation capacities of neural stem cells

Human waste-derived nutrient can help sustain agriculture, economies

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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