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Machine learning pinpoints genes that enable plants to grow more with less fertilizer

Machine learning can pinpoint "genes of importance" that help crops to grow with less fertilizer, according to a new study published in Nature Communications. It can also predict additional traits in plants and disease outcomes in animals, illustrating its applications beyond agriculture.

25 Sep 2021

Novel antibody candidate shows potent binding to diverse SARS-CoV-2 variant mutations

Twist Bioscience Corporation (Nasdaq: TWST) today reported that its internally-discovered antibody candidate TB202-3 (CoVIC-094), demonstrated potent binding to diverse SARS-CoV-2 variant mutations, including strains with the E484K, N501Y, D614G, Y453F and K417N mutations in pseudovirus assays, indicating this therapeutic antibody may be effective in treating many strains of COVID-19.

25 Sep 2021

Researchers describe a novel role for hnRNP E1 protein in binding DNA in the nucleus

Cancer is a devastating disease and is the second leading cause of death in the U.S. One of the hallmarks of cancer is genomic instability, or the tendency to accumulate mutations and damage to the DNA that leads to genome alterations during cell division.

25 Sep 2021

Research explores the evolution and function of human growth hormone receptor gene

A new study delves into the evolution and function of the human growth hormone receptor gene and asks what forces in humanity's past may have driven changes to this vital piece of DNA.

25 Sep 2021

The Lundquist Institute receives $5 million CIRM grant for a stem-cell focused program

The Lundquist Institute announced that it has received a generous $5 million, 5-year grant from the California Institute for Regenerative Medicine that will allow its PhD students, postdoctoral fellows and clinical fellows to pursue careers in stem cell biology and regenerative medicine.

24 Sep 2021

New 3D pancreatic cancer model could be used to develop and test targeted treatments

An international team of scientists have created a three-dimensional (3D) pancreatic cancer tumour model in the laboratory, combining a bioengineered matrix and patient-derived cells that could be used to develop and test targeted treatments.

24 Sep 2021

Small molecule drug can attenuate the triggers of neuroinflammation, preclinical study shows

Neuroinflammation can worsen outcomes in stroke, traumatic brain injury, or spinal cord injury, as well as accelerate neurodegenerative diseases like ALS, Parkinson's, or Alzheimer's. This suggests that limiting neuroinflammation may represent a promising new approach to treat neurological diseases and neuropathic pain that are driven by neuroinflammation.

24 Sep 2021

Study identifies master regulator behind the development of antibody-producing cells

The master regulator behind the development of antibody-producing cells has been identified in a study by investigators at Weill Cornell Medicine. The findings provide new insight into the inner workings of the immune system and may help understand how tissues develop and how certain cancers arise.

24 Sep 2021

Researchers discover how Rift Valley fever virus enters cells

Rift Valley fever virus causes economically devastating outbreaks of hemorrhagic fever in livestock such as sheep, goats and cattle.

24 Sep 2021

Research shows ozone as a potential disinfectant agent in public transport

The Hydrens team of researchers developed a numerical model that estimates the ozone concentration needed to meet the disinfection criteria. To do this, it takes into account the geometry and volume of the space to be treated, the type of materials inside it and their capacity to absorb ozone, and the characteristics of the impulsion-distribution system used.

24 Sep 2021

Exploring the polymerase of poxviruses at an atomic level

Poxviruses have found a unique way of translating their genes into proteins in the infected organism. A team of researchers from Würzburg shows for the first time how the molecular machinery involved works at an atomic level.

24 Sep 2021

New discovery offers clues to overcoming resistance to cancer therapies

Cancer cells proliferate despite a myriad of stresses - from oxygen deprivation to chemotherapy - that would kill any ordinary cell.

23 Sep 2021

Scientists characterize new genetic variants that cause nonsyndromic neurodevelopmental disorder

Northwestern Medicine scientists have characterized several variants of the gene GRIK2 that cause nonsyndromic neurodevelopmental disorder (NDD), according to a study published in the American Journal of Human Genetics.

23 Sep 2021

Discovery points toward a new strategy for treating Parkinson's disease

University of Utah Health scientists have identified a molecule that slows cells' production of alpha-synuclein, a protein that forms toxic aggregates in the brains of people with Parkinson's disease.

23 Sep 2021

Neuroscientists discover how associative memories are formed

Has the scent of freshly baked chocolate chip cookies ever taken you back to afternoons at your grandmother's house? Has an old song ever brought back memories of a first date? The ability to remember relationships between unrelated items (an odor and a location, a song and an event) is known as associative memory.

23 Sep 2021

DNA sensor can detect infectious viruses in minutes

A new sensor can detect not only whether a virus is present, but whether it's infectious – an important distinction for containing viral spread.

23 Sep 2021

Study provides novel insights into how KLF4 influences gene expression

A team led by researchers at Baylor College of Medicine has discovered a mechanism by which transcription factor KLF4 can help to organize chromatin, thus influencing gene expression.

23 Sep 2021

Bubble and droplet formation theory inspires a framework for engineering living cells

The heady math that describes how bubbles form in a glass of Champagne has inspired a framework for engineering living cells.

23 Sep 2021

Immune cells in the brain join together to break down toxic proteins more quickly

To break down toxic proteins more quickly, immune cells in the brain can join together to form networks when needed. This is shown by a joint study of the University of Bonn, the German Center for Neurodegenerative Diseases, and the Institut François Jacob in France.

23 Sep 2021

UW research provides a basic structure of neural networks in the mammalian brain

Two University of Wyoming researchers decided to pick each other's brain, so to speak. Specifically, they examined the importance of the frontal cortex, the portion of the brain used in decision-making, expressive language and voluntary movement.

22 Sep 2021

Life Science News

Machine learning pinpoints genes that enable plants to grow more with less fertilizer

Novel antibody candidate shows potent binding to diverse SARS-CoV-2 variant mutations

Researchers describe a novel role for hnRNP E1 protein in binding DNA in the nucleus

Research explores the evolution and function of human growth hormone receptor gene

The Lundquist Institute receives $5 million CIRM grant for a stem-cell focused program

New 3D pancreatic cancer model could be used to develop and test targeted treatments

Small molecule drug can attenuate the triggers of neuroinflammation, preclinical study shows

Study identifies master regulator behind the development of antibody-producing cells

Researchers discover how Rift Valley fever virus enters cells

Research shows ozone as a potential disinfectant agent in public transport

Exploring the polymerase of poxviruses at an atomic level

New discovery offers clues to overcoming resistance to cancer therapies

Scientists characterize new genetic variants that cause nonsyndromic neurodevelopmental disorder

Discovery points toward a new strategy for treating Parkinson's disease

Neuroscientists discover how associative memories are formed

DNA sensor can detect infectious viruses in minutes

Study provides novel insights into how KLF4 influences gene expression

Bubble and droplet formation theory inspires a framework for engineering living cells

Immune cells in the brain join together to break down toxic proteins more quickly

UW research provides a basic structure of neural networks in the mammalian brain

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

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