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Newly approved gene therapy for SMA is based on delivery vehicle discovered by Penn expert

James Wilson, MD, PhD, recalls being struck by the devastating toll of rare diseases as a young physician in the 1980s. He set out on a path to correct the genes that cause these conditions, including spinal muscle atrophy (SMA), the most common inherited fatal disease in infants.

25 May 2019

Prostate cancer marker activates growth factors that contribute to tumor spread

A new study indicates that PSA, a prostate cancer marker, is one of the catalysts that activate vascular endothelial and lymphangiogenic growth factors which contribute to the spread of cancer.

25 May 2019

University of Freiburg to receive 25.8 million euros for collaborative research centers

The Deutsche Forschungsgemeinschaft has approved grant applications for two collaborative research centers at the University of Freiburg: one for continued grant funding, and one for initial grant funding.

24 May 2019

Are fruit fly 'avatars' the next step in personalized medicine?

Researchers have created fruit fly “avatars” that have helped to guide treatment for a man who had terminal colon cancer.

24 May 2019

Cell scientist receives $1.9 million NIH grant to study muscle regeneration

As people age, their muscle regeneration capacity declines in part because they can no longer make enough muscle stem cells to replace damaged tissue.

24 May 2019

Johns Hopkins researchers develop method to map retinal cell development

Johns Hopkins Medicine researchers report they have created a method of mapping how the central nervous system develops by tracking the genes expressed in cells.

24 May 2019

Scientist studies people with Cockayne syndrome, who don’t get cancer

Hua-Ying Fan, PhD, studies the cells of people who don't get cancer. These people have an inherited disorder called Cockayne syndrome and, unfortunately, they don't live long enough to develop cancer. But by studying their cells, Fan may be able to help them and help people with cancer, too.

24 May 2019

LABVOLUTION highlights developments and future trends in lab technology

For anyone keen on experiencing the very latest in lab technology, LABVOLUTION was the place to be. Three major trends – automation, digitization and big data – featured prominently throughout the show, as reflected by a proliferation of robots and monitors at exhibitors' stands.

From LABVOLUTION 24 May 2019

Cornell University-led study creates new standard genome for widely researched worm

A new Cornell University-led study finds that the genome for a widely researched worm, on which countless studies are based, was flawed. Now, a fresh genome sequence will set the record straight and improve the accuracy of future research.

24 May 2019

Rutgers-led study pinpoints key gene linked to impaired memory in Down syndrome

Targeting a key gene before birth could someday help lead to a treatment for Down syndrome by reversing abnormal embryonic brain development and improving cognitive function after birth, according to a Rutgers-led study.

24 May 2019

Researchers map bone-marrow microenvironment to shed new light on leukemia

Stem cells are surrounded and protected by the stem-cell niche - the microenvironment - of the tissue in which they are found.

24 May 2019

New lithography method for producing complex tissues and organs

The production of artificial organs is a hot research topic. In the near future, artificial organs will compensate for the lack of organ donations and replace animal experiments.

23 May 2019

LM20 Microfluidizer efficiently disrupts a broad range of cell types

Analytik reports on how the School of Biological & Chemical Sciences at Queen Mary University, London has been using a LM20 Microfluidizer for cell disruption of a broad range of cell types including E. coli, Yeasts and Diatom.

From Analytik Ltd 23 May 2019

Longas offers Morphoseq technology for highly accurate long read sequencing on short read NGS platforms

Longas Technologies Pty Ltd, a developer of Next Generation Sequencing technologies, has provided details on its Morphoseq library prep and associated software technology at the ‘Sequencing, Finishing and Analysis in the Future’ meeting, May 21 – 23, Santa Fe, NM, USA, that enables long read sequencing on short read NGS platforms.

23 May 2019