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DNAmFitAge: A new method to incorporate physical fitness into epigenetic clocks

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 10, entitled, "DNAmFitAge: biological age indicator incorporating physical fitness."

7 Jun 2023

Ancient, virus-like protein may contribute to ALS

More than 5,000 people are diagnosed annually with ALS (amyotrophic lateral sclerosis), a fatal, neurodegenerative disease that attacks nerve cells in the brain and spinal cord, gradually robbing people of the ability to speak, move, eat and breathe.

7 Jun 2023

Gene drive technology could help eradicate malaria

Population-level changes in the genetic make-up of one of the world's deadliest animals could provide a key in the fight against malaria, proponents of a radical new technology argue.

7 Jun 2023

New insights into how aggressive cancer cells proliferate and propagate the disease

Not all cancer metastases have the same destructive effect. Researchers demonstrate different mechanisms in experiments.

7 Jun 2023

Axol Bioscience collaborates with StrataStem to deliver stem cell based ‘clinical trial in a dish’ for Alzheimer’s disease

Axol Bioscience Ltd. (Axol), a leading pluripotent stem cell technology provider for drug discovery has signed an exclusive agreement with StrataStem to access and commercialize its extensive collection of Alzheimer’s Disease (AD) patient samples.

From Axol Bioscience Ltd 7 Jun 2023

Experts provide neural evidence for the glimpsing model of speech perception

Researchers led by Dr. Nima Mesgarani at Columbia University, US, report that the brain treats speech in a crowded room differently depending on how easy it is to hear, and whether we are focusing on it. Publishing June 6th in the open access journal PLOS Biology, the study uses a combination of neural recordings and computer modeling to show that when we follow speech that is being drowned out by louder voices, phonetic information is encoded differently than in the opposite situation. The findings could help improve hearing aids that work by isolating attended speech.

7 Jun 2023

Differences in tumor mutation burden are a major reason for divergence: Study

The expected course of a patient's cancer prognosis has traditionally been judged by its type, stage and microscopic aggressiveness, but patients with the same presentation can still have widely divergent outcomes. Researchers from Vanderbilt-Ingram Cancer Center have discovered that differences in tumor mutation burden are a major reason for this divergence.

7 Jun 2023

Study reveals intricate pathway that dictates the cell’s ability to be resilient and plastic

Researchers have long thought that once a cell starts down its path of differentiation, growing into a skin cell or a liver cell or a neuron, that path could not be changed.

7 Jun 2023

How do antibiotics affect the ecology of the gut microbiome?

Each person's gut microbiome contains a specific community of microorganisms that normally remains stable for years. However, it can be thrown off balance by factors such as dietary changes, infections or medications. Antibiotics in particular have a strong influence on the microbiome. In response, microorganisms employ various resistance mechanisms, with individual bacterial populations evolving through selection of antibiotic-resistant variants. Yet, the extent and mechanisms of these processes and their impact on the ecology of the microbial community are poorly understood.

7 Jun 2023

Study sheds more light on factors that drive facultative brood parasitism

Several animal species display brood care, a phenomenon where 'caring' parents provide their offspring with food and protection against predators.

6 Jun 2023

Chain reaction: Nutritional keys to a healthier diet may lie in unraveling starch structures

The chain length distribution (CLD) of starch plays a crucial role in human health, affecting the digestibility of starch-containing foods and correlating with diseases like diabetes, cardiovascular disease, and obesity. By understanding and manipulating CLDs, it is possible to develop plant varieties that provide improved health properties in starch-based foods.

6 Jun 2023

Researchers characterize the expression of cardiac proteins during embryonic heart development

Researchers at the UNC School of Medicine, UNC McAllister Heart Institute, and the UNC Lineberger Comprehensive Cancer Center characterized the expression of thousands of cardiac proteins during eight critical stages of embryonic heart development.

6 Jun 2023

World's fastest camera can detect fluorescence from single molecules

Researchers at Kyoto University, Okinawa Institute of Science and Technology Graduate University (OIST), and Photron Limited in Japan have developed the world's fastest camera capable of detecting fluorescence from single molecules.

6 Jun 2023

Single dose of anti-Müllerian hormone gene therapy can induce long-term contraception in domestic cats

Currently there are no contraceptives capable of producing permanent sterilization in companion animals. Spaying, the surgical removal of the ovaries and uterus, is the most widely used strategy to control unwanted reproduction in female cats.

6 Jun 2023

SickKids scientists shine light on the complex genetics that underlie blood pressure regulation

Scientists at The Hospital for Sick Children (SickKids) are delving deep into the non-coding genome to unravel the complex genetics that underlie blood pressure regulation and hypertension (high blood pressure) – the leading cause of cardiovascular disease affecting 1.25 billion people worldwide.

6 Jun 2023

COLOTECT 1.0 receives market authorization from Malaysia's Medical Device Authority

Recently, BGI Genomics' COLOTECT 1.0 DNA Methylation Detection Kit for Human SDC2, ADHFE1, and PPP2R5C Genes (Real-Time PCR), Sample Pretreatment Kit for Methylation Detection, DNA Isolation Kit, Stool Sample Collection Kit have received market authorization from Malaysia's Medical Device Authority (hereinafter referred to as MDA).

6 Jun 2023

Breakthrough: Sequencing functional antibody proteins directly from human blood

Rapid Novor Inc., the world’s leader in mass spectrometry (MS)-based antibody protein sequencing, announced today that its REpAb® antibody discovery platform was used to successfully sequence a complex mixture of functional antibodies directly from the serum of a human patient after receiving a COVID-19 vaccine.

6 Jun 2023

ELRIG UK Announces Prof Janet Hemingway and Dr Dave Powell as Keynote Speakers at Drug Discovery 2023

ELRIG Drug Discovery 2023 at ACC Liverpool (18–19 October) to focus on diverse thinking and new perspectives.

From ELRIG (UK) Ltd. 6 Jun 2023

Fine-tuning cell mechanics stimulates hair growth: Study

Just as people's joints can get stiff as they age and make it harder for them to move around, hair follicle stem cells also get stiff, making it harder for them to grow hair, reports a new Northwestern Medicine study.

6 Jun 2023

ISSCR proposes new guidelines for using stem cells in research

The International Society for Stem Cell Research (ISSCR) today released the ISSCR Standards for Human Stem Cell Use in Research, an international collaboration aimed at enhancing rigor in preclinical research and ultimately strengthening the pipeline of therapies for patients.

6 Jun 2023

Life Science News

DNAmFitAge: A new method to incorporate physical fitness into epigenetic clocks

Ancient, virus-like protein may contribute to ALS

Gene drive technology could help eradicate malaria

New insights into how aggressive cancer cells proliferate and propagate the disease

Axol Bioscience collaborates with StrataStem to deliver stem cell based ‘clinical trial in a dish’ for Alzheimer’s disease

Experts provide neural evidence for the glimpsing model of speech perception

Differences in tumor mutation burden are a major reason for divergence: Study

Study reveals intricate pathway that dictates the cell’s ability to be resilient and plastic

How do antibiotics affect the ecology of the gut microbiome?

Study sheds more light on factors that drive facultative brood parasitism

Chain reaction: Nutritional keys to a healthier diet may lie in unraveling starch structures

Researchers characterize the expression of cardiac proteins during embryonic heart development

World's fastest camera can detect fluorescence from single molecules

Single dose of anti-Müllerian hormone gene therapy can induce long-term contraception in domestic cats

SickKids scientists shine light on the complex genetics that underlie blood pressure regulation

COLOTECT 1.0 receives market authorization from Malaysia's Medical Device Authority

Breakthrough: Sequencing functional antibody proteins directly from human blood

ELRIG UK Announces Prof Janet Hemingway and Dr Dave Powell as Keynote Speakers at Drug Discovery 2023

Fine-tuning cell mechanics stimulates hair growth: Study

ISSCR proposes new guidelines for using stem cells in research

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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