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Manipulating white blood cells to eliminate solid tumors

By silencing the molecular pathway that prevents macrophages from attacking our own cells, Penn Engineers have manipulated these white blood cells to eliminate solid tumors.

12 Jun 2023

New cell culture model generates the alveolar macrophage in the lab

Researchers at Texas Biomedical Research Institute have succeeded in generating the lung's most important immune cell, the alveolar macrophage, in the lab.

12 Jun 2023

Researchers create a new method of studying nano-sized particles

Researchers at Karolinska Institutet have created a new method of studying the smallest bioparticles in the body.

12 Jun 2023

Study raises new hopes for blood cancer patients with an incomplete response to CAR T cell therapy

The aim of immunotherapy strategies is to use cells in the patient's own immune system to destroy tumor cells. CAR T cell therapy is an immunotherapy that is effective in treating blood cancer.

12 Jun 2023

Researchers discover how a sugar molecule can affect cancer cell response to chemoradiotherapy

Researchers at Georgetown University's Lombardi Comprehensive Cancer Center and colleagues who have been exploring the complexities of biochemical pathways involved in cancer development have found that a form of glucose, a type of sugar, is intricately linked to a pathway used to build DNA molecules.

12 Jun 2023

New material could usher in the next generation of cancer treatments

A new material, created at the little-explored intersection of organic and inorganic chemistry, could not only enable more powerful solar panels, but it could also usher in the next generation of cancer treatments.

12 Jun 2023

Study reveals how p62 bodies control redox-independent stress response

Cellular stress, or oxidative stress, occurs when there is a buildup of reactive oxygen species (ROS), which interferes with cellular mechanisms and can even cause damage to proteins, lipids, and DNA.

12 Jun 2023

Vaccine against deadly chytrid fungus shifts microbiome to make frogs more resilient to future exposure

A human or animal's microbiome -; the collection of often beneficial microorganisms, including as bacteria and fungi, that live on or within a host organism -; can play an important role in the host's overall immune response, but it is unclear how vaccines against harmful pathogens impact the microbiome.

11 Jun 2023

Researchers identify microRNAs associated with a weakened immune response to COVID-19

A team of researchers at NYU Abu Dhabi, led by Associate Professor of Biology Youssef Idaghdour and working in collaboration with clinicians at several Abu Dhabi hospitals, investigated the association between microRNAs, a class of small RNA molecules that regulate genes, and COVID-19 severity among 259 unvaccinated COVID-19 patients living in Abu Dhabi.

11 Jun 2023

Genetic counselling for familial colorectal cancer provides improves patients' feelings of empowerment

Genetic counselling is essential when dealing with individuals who are affected by, or at risk of, inherited disease.

11 Jun 2023

Study unveils potential early detection algorithm for neurodegeneration in rare genetic disorder

Xeroderma pigmentosum (XP) is a rare and devastating genetic disorder characterised by an inability to repair skin damage caused by ultraviolet (UV) light.

11 Jun 2023

Common genetic factors could be used to identify individuals at high risk of developing colorectal cancer

Rates of colorectal cancer are high despite widespread adoption of screening programs in many high-income European countries.

11 Jun 2023

Keynote speakers of ELRIG Drug Discovery 2023 announced

The European Laboratory Research & Innovation Group (ELRIG) UK today announced the keynote speakers for Drug Discovery 2023, taking place at the ACC in Liverpool from 18–19 October. Prof Janet Hemingway CBE, FRS, Founding Director of Infection Innovation Consortium (iiCON), and Dr Dave Powell, Chief Scientific Officer (CSO) of LifeArc will lead this year’s event focussing on diverse thinking and new perspectives.

10 Jun 2023

Researchers create first integrated single-cell atlas of the human lung

The largest and most comprehensive cell map of the human lung is announced in Nature Medicine today (8 June). Revealing the great diversity of cell types in the lung and key differences between health and disease, the Human Lung Cell Atlas will be a valuable resource for lung researchers.

10 Jun 2023

AI system in eye scans enables better diagnosis of inherited retinal diseases

Inherited retinal diseases (IRDs), single-gene disorders affecting the retina, are very difficult to diagnose since they are uncommon and involve changes in one of many candidate genes.

9 Jun 2023

Combining blood biomarkers with genomics could provide useful information about disease risk

Being to identify people at high risk of chronic disease means that they can be targeted with prevention measures before they become sick.

9 Jun 2023

ABCC9 gene variants influence the pitch of voices

In a paper published today in Science Advances, an international team led by deCODE genetics, a subsidiary of Amgen, reveals the discovery of sequence variants in the gene ABCC9 that influence the pitch of voices.

9 Jun 2023

New method to escape from metastability in a far-from-equilibrium system of DNA-functionalized colloids

Prof. Liang Haojun from the University of Science and Technology of China (USTC) of the Chinese Academy of Sciences (CAS) proposed a new method to escape from metastability for self-assembly in a far-from-equilibrium system.

9 Jun 2023

New model can quickly screen large libraries of potential drug compounds

Huge libraries of drug compounds may hold potential treatments for a variety of diseases, such as cancer or heart disease.

9 Jun 2023

Scientists determine the atomic-level structure of a zinc-transporter protein

Scientists at the U.S. Department of Energy's (DOE) Brookhaven National Laboratory have determined the atomic-level structure of a zinc-transporter protein, a molecular machine that regulates levels of this crucial trace metal micronutrient inside cells.

9 Jun 2023

Life Science News

Manipulating white blood cells to eliminate solid tumors

New cell culture model generates the alveolar macrophage in the lab

Researchers create a new method of studying nano-sized particles

Study raises new hopes for blood cancer patients with an incomplete response to CAR T cell therapy

Researchers discover how a sugar molecule can affect cancer cell response to chemoradiotherapy

New material could usher in the next generation of cancer treatments

Study reveals how p62 bodies control redox-independent stress response

Vaccine against deadly chytrid fungus shifts microbiome to make frogs more resilient to future exposure

Researchers identify microRNAs associated with a weakened immune response to COVID-19

Genetic counselling for familial colorectal cancer provides improves patients' feelings of empowerment

Study unveils potential early detection algorithm for neurodegeneration in rare genetic disorder

Common genetic factors could be used to identify individuals at high risk of developing colorectal cancer

Keynote speakers of ELRIG Drug Discovery 2023 announced

Researchers create first integrated single-cell atlas of the human lung

AI system in eye scans enables better diagnosis of inherited retinal diseases

Combining blood biomarkers with genomics could provide useful information about disease risk

ABCC9 gene variants influence the pitch of voices

New method to escape from metastability in a far-from-equilibrium system of DNA-functionalized colloids

New model can quickly screen large libraries of potential drug compounds

Scientists determine the atomic-level structure of a zinc-transporter protein

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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