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Combination of genetic and environmental factors increases the risk of cleft lip

A cleft lip or palate arises from the combined effects of genes and inflammatory risk factors experienced during pregnancy, such as smoking or infections, finds a new study led by UCL researchers.

24 May 2023

Exploring how stress might be communicated to other animals

Heat-stressed fish embryos release chemical signals that change the appearance, behavior, and development of fish embryos that were not heat stressed, according to a study.

24 May 2023

Scientists study the structure and function of a transporter involved in cancer, immunity

Scientists at St. Jude Children's Research Hospital and the University of Texas Southwestern Medical Center studied the structure and function of a transporter involved in cancer and immunity.

24 May 2023

Study characterizes how the inflammatory microenvironment of adult mouse prostate changes during aging

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 9, entitled, "Highly multiplexed immune profiling throughout adulthood reveals kinetics of lymphocyte infiltration in the aging mouse prostate."

24 May 2023

Oxygen restriction associated with longer lifespan in lab mice

For the first time, researchers have shown that reduced oxygen intake, or "oxygen restriction", is associated with longer lifespan in lab mice, highlighting its anti-aging potential.

24 May 2023

Looking at cancer drugs to help put the brakes on classic indicators of aging

Antiretroviral cocktails can make human immunodeficiency virus, or HIV, undetectable and untransmittable, but both the virus and its treatment can also accelerate aging of bone and muscle.

24 May 2023

Academic paper: AI is advantageous in all aspects of new drug research and development

Scientists have long been challenged by the complex process of drug discovery and development, with investments that often go unrewarded.

23 May 2023

$Using 3D-electron diffraction to determine the structure of Levocetirizine dihydrochloride$

Using 3D-electron diffraction to determine the structure of Levocetirizine dihydrochloride

For pharmaceuticals, knowing the chemical composition is not enough-;molecular geometry and crystal structure also play an important role in a drug's activity.

23 May 2023

GPR141 drives breast tumorigenesis by inducing tumor cell properties via the p-mTOR1/p53 axis

A new research paper was published in Oncotarget's Volume 14 on May 19, 2023, entitled, "G-protein-coupled receptor 141 mediates breast cancer proliferation and metastasis by regulating oncogenic mediators and the p-mTOR/p53 axis."

23 May 2023

Contraception ends same-sex sexual behavior’s genetic maintenance in modern societies

Evolution depends on genes being passed down through the generations via reproduction, and same-sex sexual behavior does not result in offspring.

23 May 2023

39th Barcelona BioMed Conference focuses on latest advances in proximity induction-based pharmacology

Targeted protein degradation uses different types of "degrading" drugs (degraders) to force proximity between a target protein (for example, a mutated protein that contributes to the development of a disease) and the cellular machinery that directs protein degradation.

23 May 2023

Cytoelectric Coupling hypothesis: Fluctuating electric fields shape the brain’s molecular infrastructure

To produce its many functions, including thought, the brain works at many scales. Information such as goals or images is represented by coordinated electrical activity among networks of neurons, while within and around each neuron a mix of proteins and other chemicals physically carries out the mechanics of participating in the network.

22 May 2023

Newly developed method can help identify the special differences in genetic information

Plants show enormous variety in traits relevant to breeding, such as plant height, yield and resistance to pests.

22 May 2023

Researchers produce a multi-scale map of protein assemblies in the DNA damage response

Writing in the May 22, 2023 issue of Cell Systems, a diverse team of scientists, led by researchers at University of California San Diego School of Medicine, have produced a novel map that depicts the human body's enormously complicated and highly evolved system for addressing and repairing DNA damage -; a cause and consequence of many diseases.

22 May 2023

Life Science News

Combination of genetic and environmental factors increases the risk of cleft lip

Exploring how stress might be communicated to other animals

Scientists study the structure and function of a transporter involved in cancer, immunity

Study characterizes how the inflammatory microenvironment of adult mouse prostate changes during aging

Oxygen restriction associated with longer lifespan in lab mice

Looking at cancer drugs to help put the brakes on classic indicators of aging

Academic paper: AI is advantageous in all aspects of new drug research and development

Using 3D-electron diffraction to determine the structure of Levocetirizine dihydrochloride

GPR141 drives breast tumorigenesis by inducing tumor cell properties via the p-mTOR1/p53 axis

Contraception ends same-sex sexual behavior’s genetic maintenance in modern societies

39th Barcelona BioMed Conference focuses on latest advances in proximity induction-based pharmacology

Cytoelectric Coupling hypothesis: Fluctuating electric fields shape the brain’s molecular infrastructure

Newly developed method can help identify the special differences in genetic information

Researchers produce a multi-scale map of protein assemblies in the DNA damage response

Surviving without glucose: uridine-derived ribose as an alternative energy source

Understanding the cause for suboptimal germinal center response in aged mice

Dad’s genome may be playing a bigger role in siblings born with ASD

Honokiol inhibits replication of SARS-CoV-2 in several cell types

AI-based method predicts small molecule substrates of enzymes

Newly discovered molecule effectively destroys senescent cells

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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