Life Science White Papers are in-depth articles aimed to educate and inform site visitors interested in life science research. Some of these papers are derived from sources where we have existing commercial relationships. Such articles are clearly labelled as sponsored content and are only accepted when the content is deemed to add value to the core editorial ethos of News Medical.
In this article, Sphere Fluidics discusses the best practices for enhancing cell line development and how to implement them in research and development.
In this article, Sphere Fluidics showcases a high-throughput method of effectively identifying and isolating rare cells that secrete antibodies.
Picodroplet technology has had a transformative effect on single cell analysis. This article delves into a few of the major issues encountered with picodroplets and how to potentially overcome them.
Single cells are valuable biological reagents, but production and cloning of them can be an issue. This article dives into a novel method of cloning through microfluidics.
In this article, Sphere Fluidics demonstrates how they overcome common obstacles in biotherapeutic development in order to enhance production.
In this article, Sphere Fluidics demonstrates how its hydrogel technologies are utilized in cell culture and cell analysis processes, especially with regard to high-throughput analysis of cell populations.
Cell line development is a process that is critical to biopharmaceutical development. As cell lines must be cloned from a single cell progenitor to ensure consistency, it is thus important to be able to find and isolate high-producing clones.
In this article, Sphere Fluidics discusses how the high-throughput function verification of CAR-T cell function is achieved in microfluidic picodroplets and the implications this could have for immuno and cell therapy.
While cell line development technologies continue to improve, there are still numerous hurdles to overcome. This article discusses the biggest challenges in cell line development and how to overcome them.
High-throughput B cell screening is an incredibly useful tool in the development of therapeutic antibodies. It rapidly decreases lead discovery times and as such is an area of high interest.
In this article, Sphere Fluidics demonstrates how its Cyto-Mine® instrument has been crucial in the acceleration of hybridoma-based antibody discovery.
Streamlined antibody discovery processes are of paramount importance to therapeutic development, single B cell screening is a major part of this and thus an optimized, high-throughput process is incredibly useful.
The Cyto-Mine® is a crucial tool in cell line development. This case study demonstrates how FUJIFILM Diosynth Biotechnologies incorporated the Cyto-Mine® into its processes and research into cell lines.
In this article, Sartorius discusses the uptake of small molecules across cell membranes.
In this article, Sartorius discusses how to evaluate instrument data integrity in a lab and provides a checklist of important steps to cover.
Uniform picoliter volume droplets, also known as picodroplets, can be utilized as 'test tubes' for high-throughput bioassays. The utilization of picodroplets allows for novel bioassays to be used, thus aiding biotherapeutic development, cell therapy, genome editing, and more.
In this article, ACROBiosystems demonstrates how their GMP-grade protein services can aid in the manufacturing of cell therapeutics.
At Pittcon, the emphasis will be placed on how microfluidics can improve bioanalysis and various innovative applications in life sciences. Read more here
In this article, Sartorius introduces 10 of the most common applications for live cell analysis in immunology, discussing their importance, methods, and more.
This article from Thermo Fisher discusses a study published in 2022 where researchers used the Thermo Scientific™ Amira™ Software along with serial block-face scanning electron microscopy (SBF SEM). The result was that they were able to produce detailed 3D reconstructions of organelles.