Life Science White Papers

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Life Science White Papers are in-depth articles aimed to educate and inform site visitors interested in life science research. Some of these papers are derived from sources where we have existing commercial relationships. Such articles are clearly labelled as sponsored content and are only accepted when the content is deemed to add value to the core editorial ethos of News Medical.

Industrial Hearing Loss

Industrial hearing loss (also known as occupational deafness or noise-induced hearing loss) is hearing impairment due to prolonged exposure to excessive noise at work. Although its prevalence is falling after the introduction of acts to control noise levels in the workplace, it still affects 14,000 people in the UK and 10,000,000 people in the US.

From Hampson Hughes Solicitors 30 Apr 2014

Research-Grade Microscopy Cameras Offer Imaging Solutions for Digital Pathology Applications

Digital pathology refers to the digitizing of glass slides to provide image-based information for diagnostic, analytical and educational purposes. Telepathology is pathology that is performed at a distance, usually using digital pathology. Therefore, these two practices are closely interlinked and enjoy considerable overlap.

From Teledyne Lumenera 3 Apr 2014

APOLLO Raman Microspectrometer for Pharmaceutical Monitoring

Pharmaceutical monitoring is an integral part of the production, testing and manufacturing process.

From CRAIC Technologies, Inc. 3 Apr 2014

Solid-state ChIP Platform for High Throughput Analysis of Gene Regulation

In recent years, epigenetics has become an increasingly important focus in the worlds of academia and industry as researchers try to better understand the fundamental s of transcription regulation. Developments in high throughput ChIP together with the use of automated liquid handing and next generation sequencing is laying the foundations for analysis of global gene expression and understanding the epigenetic landscape in a huge number of cell types across a variety of diseases and treatments.

From Chromatrap® - Porvair Sciences Ltd 19 Mar 2014

Chromatrap 96 High Throughput ChIP for Screening Multiple Epigenetic Targets

Advancements in the field of epigenetics are rapidly growing as researchers elucidate the principles controlling gene regulation via the in vivo binding of proteins to DNA. A major aspect in this is the need to study a vast number of regulatory mechanisms to map interactions between DNA and protein following disease and pathogen stimulus.

From Chromatrap® - Porvair Sciences Ltd 17 Mar 2014

Chromatrap Immunoprecipitation Assay Enriches Epigenetic Histone Methylation Marks from Primary Biopsy Samples

The uterus is a pear-shaped organ that consists of a lower barrel shaped cervix and a large upper body with the 'fundus' over the uterine tubes. It has a thick muscular wall, which houses the human fetus from conception to birth.

From Chromatrap® - Porvair Sciences Ltd 17 Mar 2014

Using Chromatrap Pro-A 1ml Columns for Breast Tissue Chromatin Enrichment

CTCF is a highly conserved eleven zinc finger transcription factor, which specially binds to various divergent DNA sequences. This multifunctional and ubiquitously expressed transcription factor is a main factor in regulating cell growth, as it controls major regulators of cell proliferation, for instance, activates p14ARF/p19ARF and represses c-myc genes. The CTCF gene itself is re-arranged in several clinical tumour samples and cancer cell lines. Therefore, indirect evidence implies that CTCF could be a new tumour suppressor gene.

From Chromatrap® - Porvair Sciences Ltd 17 Mar 2014

Chromatrap® Technology for Studying Complex Epigenetic Mechanisms

Chromatin immunoprecipitation (ChIP) is a widely used technique for mapping the interactions between intracellular proteins and their DNA targets in gene regulation. The epigenetic mechanisms that affect chromatin formation and control the availability of the DNA backbone to transcription factor regulators is an important area of research. ChIP is a technology that allows researchers a glimpse into the regulatory mechanisms that gene expression.

From Chromatrap® - Porvair Sciences Ltd 17 Mar 2014

Setting Effective Product Specifications in Pharmaceutical Manufacturing

An important aspect of Quality by Design (QbD) is to establish meaningful and realistic specifications. Well-defined specifications control the performance of products, as they derive from associations between clinical behaviour and the variables determined routinely during processing for quality control. This article investigates the process of setting specifications, taking particle size as an example which is a major parameter for a variety of pharmaceutical formulations.

From Malvern Panalytical 17 Mar 2014

Using Ultraviolet Microscopy and Microspectroscopy for Analysis of Red Blood Cells

One of the most important techniques used for analyzing biological materials is UV-visible range microspectroscopy.

From CRAIC Technologies, Inc. 3 Feb 2014

DNA Analysis with UV-Visible Microspectroscopy

In forensics laboratories, one of the most frequently used techniques is DNA analysis with UV-visible microspectroscopy.

From CRAIC Technologies, Inc. 3 Feb 2014

Using Absorbance Microspectroscopy to Analyze Biocrystalline Materials

UV-visible range microspectroscopy is one of the most useful techniques for studying individual protein crystals.

From CRAIC Technologies, Inc. 3 Feb 2014

Darkfield Hyperspectral Imaging for Analysis of Nanoparticles in Cancer Cells

Biological samples typically contain nanomaterials that scatter light significantly, and these samples are usually studied with dark field illumination. When dark field illumination is combined with hyperspectral imaging, it becomes a unique tool that can be used for identifying the location and composition of nanomaterials embedded in cells. To this end, the IMA hyperspectral imager supplied by Photon etc can be used for this application. A high-efficient dark field condenser can be fitted to this hyperspectral imager to produce high contrast images of biological samples.

From Photon etc. 22 Jan 2014

Opticare and Lumenera Collaborate on Ophthalmic Disease Diagnosis

Opticare based in Argentina has been providing technology for diagnosis and treatment of ophthalmic diseases for more than 35 years. Opticare was established by its President Pedro Faulhaber and has grown to be recognized as the premier distributor of ophthalmic instruments including Topcon Ophthalmic Instrumentation, Excimer Lasers, and Fundus cameras used for photographing the interior of the eye.

From Teledyne Lumenera 13 Jan 2014

Lumenera’s Microscopy Camera helps Achieve Pathology Expertise

Dr Gerald Kolaja established Balboa BioConsulting in 2008. He is an ACVP board certified veterinary pathologist with over 30 years experience in pathology and pharmaceutical development.

From Teledyne Lumenera 12 Jan 2014

Lumenera’s INFINITY Cameras Selected by University of Ottawa Biology Department as Imaging Solution

The microscopy stations of the University of Ottawa undergraduate students were newly equipped with Lumenera’s INFINITY2-3 and INFINITY3-1color digital cameras.

From Teledyne Lumenera 12 Jan 2014

Lumenera Cameras Selected by Dermatopathology Lab for Speed and Clarity in Microscopy

Ball Dermpath is a new, physician-owned dermatopathology practice in Greensboro, NC. They have a team of experienced technologists, doctors and case managers that offer excellent diagnostic services. Their novel, highly personalized and convenient reporting platform is appreciated by busy practice nurses, administrators and physicians.

From Teledyne Lumenera 12 Jan 2014

CooperSurgical aided by Lumenera in Women's Health Care Worldwide

CooperSurgical has a portfolio of products and brands that define and advance women's health care. Their products are available in hospitals, physician offices and assisted reproductive technology clinics through a network of direct, indirect and distributor sales teams.

From Teledyne Lumenera 12 Jan 2014

Using Fluorescence Lifetime Technique in Luminescence Measurements

Despite the complementary nature of the fluorescence lifetime technique, most users found this unsuitable because of the size, cost and complexity involved to operate the instrument. Although the cost of instruments has reduced considerably, including the size and complexity of operation, before the introduction of the new EasyLife-X system, some users were still wary of using the fluorescence lifetime technique.

From Optical Building Blocks Corporation 4 Dec 2013

Benefits of Using Scanning Monochromators in Fluorometric Experiments Investigating Intracellular Cation Concentrations

In ratio fluorometric experiments a scanning monochromator is useful for investigating intracellular cation concentrations. This article describes the various benefits of using the scanning monochromator.

From Optical Building Blocks Corporation 4 Dec 2013