Life Science White Papers

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Life Science White Papers are in-depth articles aimed to educate and inform site visitors interested in life science research. Some of these papers are derived from sources where we have existing commercial relationships. Such articles are clearly labelled as sponsored content and are only accepted when the content is deemed to add value to the core editorial ethos of News Medical.

Using Taylor Dispersion Analysis to Evaluate Stability and Self-Association of Insulin Under Different Formulation Conditions

Using Taylor Dispersion Analysis to Evaluate Stability and Self-Association of Insulin Under Different Formulation Conditions

Taylor dispersion analysis (TDA) is an orthogonal method for stability and sizing analyses of biomolecules in solution. Previous research has shown that hydrodynamic radius (Rh) measurements from TDA on monoclonal antibodies (mAbs) and other monodisperse systems are similar to data acquired using dynamic light scattering (DLS), a well-known, complementary method.

From Malvern Panalytical 30 Jul 2015

Understanding the Antioxidant Properties of Coffee

Understanding the Antioxidant Properties of Coffee

As one of the most popular and widely consumed drinks, coffee has long been a staple of breakfast tables and cafes worldwide. But, more recently, research has begun to reveal the benefits of coffee that go beyond a pick-me-up and could have a genuine impact on our health.

From Bruker BioSpin - NMR, EPR and Imaging 20 Jul 2015

VUmc, Xenics TeamUp in Thermography Project for Clinical Research Programs

VUmc, Xenics TeamUp in Thermography Project for Clinical Research Programs

Xenics is a Europe-based company specializing in the development and manufacture of next-generation infrared cameras, imagers, and customized imaging systems that range from the LWIR to the visible spectrum. The company has teamed up with the VU University Medical Center (VUmc) of Amsterdam, The Netherlands, for the development of ground-breaking clinical research programs.

From Xenics 6 Jul 2015

Using the SPECTROstar Nano for Testing Free Amino Nitrogen Content in Alcoholic Beverages

Using the SPECTROstar Nano for Testing Free Amino Nitrogen Content in Alcoholic Beverages

Testing for free amino nitrogen is standard brewing quality control analysis. Estimated protein content serves as an indicator of beer quality.

From BMG LABTECH GmbH 2 Jul 2015

Quality Control of Distilled Spirits and Beer Using SPECTROstar Nano

Quality Control of Distilled Spirits and Beer Using SPECTROstar Nano

SPECTROstar Nano and Brewing and Distilling Analytical Services, LLC, have been key to advancing the quality of the testing and analysis of alcohol beverages.

From BMG LABTECH GmbH 2 Jul 2015

Using IP-One HTRF® Assay to Identify Low Affinity Compounds

Using IP-One HTRF® Assay to Identify Low Affinity Compounds

This article describes the IP-One HTRF® assay from Cisbio carried out using two different HTS microplate readers with different detection technologies.

From BMG LABTECH GmbH 2 Jul 2015

Microplate Readers for HTRF Measurements

Microplate Readers for HTRF Measurements

Chronic damage or injury to nerves causes changes in the primary sensory neurons located in the dorsal root ganglion (DRG) and in their central connections.

From BMG LABTECH GmbH 2 Jul 2015

RT-QuIC: Faster, Higher Throughput Assay for Prion Seeding

RT-QuIC: Faster, Higher Throughput Assay for Prion Seeding

Prions cause irregular folding of a brain protein in both animals and humans, which leads to brain damage and is fatal.

From BMG LABTECH GmbH 2 Jul 2015

CLARIOstar High-Performance Microplate Reader with Next Generation LVF Monochromators

CLARIOstar High-Performance Microplate Reader with Next Generation LVF Monochromators

BMG LABTECH specializes in microplate reading systems including the CLARIOstar High-Performance Microplate Reader with Next Generation LVF Monochromators.

From BMG LABTECH GmbH 2 Jul 2015

CLARIOstar® with New Atmospheric Control Unit Offers Versatility in Long Term Cell-Based Assays

CLARIOstar® with New Atmospheric Control Unit Offers Versatility in Long Term Cell-Based Assays

Cell based assays are versatile and powerful tools used in the research lab, analyses of cytotoxicity and cell viability are used to detect real-time changes.

From BMG LABTECH GmbH 1 Jul 2015

Characterization of Protein Stability Using Differential Scanning Calorimetry

Characterization of Protein Stability Using Differential Scanning Calorimetry

Christian Anfinsen carried out advanced experiments which clearly showed that the linear string of amino acids in a protein encodes all the information for its 3D structure.

From TA Instruments 24 Jun 2015

Characterization of Binding Interactions Using Isothermal Titration Calorimetry

Characterization of Binding Interactions Using Isothermal Titration Calorimetry

Biochemical reactions are regulated by enzymes. These reactions involve binding, recognition, and the creation of non-covalent complexes.

From TA Instruments 24 Jun 2015

Using ITC Technique for Characterization of Protein-Protein Interactions

Using ITC Technique for Characterization of Protein-Protein Interactions

Proteins are large biological molecules that are integral to complex networks.

From TA Instruments 24 Jun 2015

iBox Scientia Imaging System to Monitor Progression of Tumor Lesions

iBox Scientia Imaging System to Monitor Progression of Tumor Lesions

This white paper outlines the use of the iBox® Scientia™ imaging system to monitor the progression of tumor lesions.

From Analytik Jena US 24 Jun 2015

In Vivo Fluorescence Imaging of Angiogenic Vessels in Liver Cancer

In Vivo Fluorescence Imaging of Angiogenic Vessels in Liver Cancer

Using the iBox Explorer Imaging Microscope for In Vivo Fluorescence Imaging of Angiogenic Vessels in HepG2-GFP Liver Cancer Mouse Model.

From Analytik Jena US 23 Jun 2015

Using Tumor-Targeting Mutant Salmonella To Treat Prostate Cancer

Using Tumor-Targeting Mutant Salmonella To Treat Prostate Cancer

This whitepaper outlines how a tumor-targeting mutant of Salmonella Typhimurium can treat mouse models of human prostate cancer.

From Analytik Jena US 23 Jun 2015

Comprehensive testing for extractables in deep well microplates

Comprehensive testing for extractables in deep well microplates

In the present study, significant contamination levels were again found in many microplate samples from a range of manufacturers. This study widens the scope of prior studies and analyzes not only “natural” polymer microplates, but also black and colored plates from a much larger range of manufacturers than before...

From Porvair Sciences Limited 28 May 2015

Using Protein Crash and Solid Phase Extraction Techniques for Biological Sample Preparation

Using Protein Crash and Solid Phase Extraction Techniques for Biological Sample Preparation

Unwanted biomolecules need to be removed from serum, blood, urine, semen, spinal fluid, and other ex-vivo samples so that quantitative analysis of tiny molecules can be performed using LC-MS systems. The main components that need removing are proteins because these macromolecules become sticky and can damage chromatography columns. These large proteins can clog up the tiny holes in chromatography columns.

From Porvair Sciences Limited 26 May 2015

Determining Well-to-Well Cross-Talk in Microplates Utilized for Luminescence Measurements

Determining Well-to-Well Cross-Talk in Microplates Utilized for Luminescence Measurements

Luminescence reagents and assays are often used in drug discovery and research, but over the last decade their use has increased considerably owing to the high specificity of assays, ease of use, and good sensitivity at low levels of screened compounds.

From Porvair Sciences Limited 26 May 2015

Using Whole-Mount Slide Scanners to Acquire High Resolution Brain Images

Using Whole-Mount Slide Scanners to Acquire High Resolution Brain Images

To gain further insight into the brain and its functions, it is necessary to atlas the brain and the connections involved.

From Huron Digital Pathology 11 May 2015

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