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Natural PLA2 inhibitor from marine fungus combats fatty liver disease by silencing lipotoxic pathways

This new article publication from Acta Pharmaceutica Sinica B, discusses the identification of a natural PLA2 inhibitor from the marine fungus Aspergillus sp. c1 for MAFLD treatment that suppressed lipotoxicity by inhibiting the IRE-1α/XBP-1s axis and JNK signaling.

16 Jan 2024

Jena researchers unravel PAPAS RNA's impact on breast cancer growth and metastasis

Breast cancer is the most common cancer in women. The development of breast cancer often originates from epithelial cells in the mammary gland – the very cells that specialise in milk production during and after pregnancy.

16 Jan 2024

"Healthy Smiles, Healthy Hearts" initiative bridges oral health and heart health

A patient's oral health can be an indicator of overall health and well-being. Research shows that chronic gum inflammation may be associated with other chronic diseases including coronary artery disease and diabetes.

16 Jan 2024

Study uncovers higher prevalence of hidradenitis suppurativa in young Finns

A new study from the University of Oulu, Finland, provides new insights into a skin condition called hidradenitis suppurativa (HS).

16 Jan 2024

Revolutionary brain scan lights up glioma's Achilles heel

Recently, a team of South Korean researchers led by nuclear medicine physician and Professor Yun Mijin from Severance Hospital in collaboration with Director C. Justin LEE of the Center for Cognition and Sociality within the Institute for Basic Science (IBS) made a new discovery that can revolutionize both the diagnosis and treatment of glioblastoma.

16 Jan 2024

New study seeks to unravel inner workings of the human brain

The inner workings of the human brain are a gradually unraveling mystery and Dr. Richard Naud of the University of Ottawa's Faculty of Medicine has led a highly compelling new study that brings us closer to answering these big questions.

16 Jan 2024

Amnesia caused by head injury could potentially be reversed, mouse study suggests

A mouse study designed to shed light on memory loss in people who experience repeated head impacts, such as athletes, suggests the condition could potentially be reversed.

16 Jan 2024

Exposure to AI models may reshape clinician's decisions and improve care outcomes

What if just observing Artificial Intelligence (AI) could make a clinician more efficient at their job and improve care outcomes for patients?

16 Jan 2024

Breakthrough nano-shield blocks selective allergic reactions

Northwestern University researchers have developed the first selective therapy to prevent allergic reactions, which can range in severity from itchy hives and watery eyes to trouble breathing and even death.

16 Jan 2024

Contact lenses monitor eye pressure for glaucoma prevention

Glaucoma effects around 70 million people worldwide and can cause irreversible loss of vision if not treated – but around half of those living with the condition are not aware of it.

16 Jan 2024

Research uncovers cells-of-origin for breast cancer in BRCA2 mutation carriers

Australian scientists have pinpointed likely 'cells-of-origin', the source cells that can grow into breast cancer, in women carrying a faulty BRCA2 gene who are at high risk of developing the disease.

16 Jan 2024

UK-wide COVID vaccination coverage study reveals gaps and preventable hospitalizations

Between a third and a half of the populations of the four UK nations had not had the recommended number of COVID vaccinations and boosters by summer 2022, according to the first research study to look at COVID-19 vaccine coverage of the entire UK population.

16 Jan 2024

Urea-powered nanorobots reduce bladder tumors by 90% in mice

The research, which was conducted on mice, demonstrates how these tiny nanomachines are propelled by urea present in urine and precisely target the tumour, attacking it with a radioisotope carried on their surface.

16 Jan 2024

Amsterdam UMC project aims for first effective HIV vaccine with Gates funding

Worldwide, an estimated, 40 million people live with HIV. Two-thirds of this group on the African continent.

16 Jan 2024

High fat mass in adolescence could worsen insulin resistance and obesity by young adulthood

High fat mass in adolescence causes insulin resistance, which can lead to a vicious cycle of worsening insulin resistance and obesity by young adulthood, a new study shows.

16 Jan 2024

New dust testing methodology better protects workers from lung diseases

A new dust testing methodology developed by University of Queensland researchers offers workers better protection from diseases such as black lung and silicosis.

16 Jan 2024

Study highlights importance of healthy eating for children's heart health

A healthier diet is associated with serum metabolite concentrations indicative of better cardiovascular health already in school-aged children, a recent study from the University of Eastern Finland shows.

16 Jan 2024

Combining health data with whole genome sequence data in cancer patients can help doctors provide more tailored care

Researchers evaluated the impact of integrating whole-genome sequencing data with clinical outcomes across 13,880 tumors from 33 cancer types, assessing precision care potentials within the UK NHS through the 100,000 Genomes Cancer Programme.

16 Jan 2024

Study finds low-dose calcium as effective as the WHO's recommended high-dose in preventing preeclampsia and preterm births

Researchers assessed the noninferiority of a 500-mg daily dose of calcium supplementation compared to a 1500-mg dose in preventing preeclampsia and preterm birth in pregnant women in India and Tanzania.

16 Jan 2024

New study shows how brain glucose affects fungal disease treatment

Metabolite-drug-fungal interactions in the fungal meningitis pathogen Cryptococcus neoformans.

16 Jan 2024

Medical News

Natural PLA2 inhibitor from marine fungus combats fatty liver disease by silencing lipotoxic pathways

Jena researchers unravel PAPAS RNA's impact on breast cancer growth and metastasis

"Healthy Smiles, Healthy Hearts" initiative bridges oral health and heart health

Study uncovers higher prevalence of hidradenitis suppurativa in young Finns

Revolutionary brain scan lights up glioma's Achilles heel

New study seeks to unravel inner workings of the human brain

Amnesia caused by head injury could potentially be reversed, mouse study suggests

Exposure to AI models may reshape clinician's decisions and improve care outcomes

Breakthrough nano-shield blocks selective allergic reactions

Contact lenses monitor eye pressure for glaucoma prevention

Research uncovers cells-of-origin for breast cancer in BRCA2 mutation carriers

UK-wide COVID vaccination coverage study reveals gaps and preventable hospitalizations

Urea-powered nanorobots reduce bladder tumors by 90% in mice

Amsterdam UMC project aims for first effective HIV vaccine with Gates funding

High fat mass in adolescence could worsen insulin resistance and obesity by young adulthood

New dust testing methodology better protects workers from lung diseases

Study highlights importance of healthy eating for children's heart health

Combining health data with whole genome sequence data in cancer patients can help doctors provide more tailored care

Study finds low-dose calcium as effective as the WHO's recommended high-dose in preventing preeclampsia and preterm births

New study shows how brain glucose affects fungal disease treatment

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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