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Stimulant users are caught in fatal ‘fourth wave’ of opioid epidemic

In Pawtucket, Rhode Island, near a storefront advertising "free" cellphones, J.R. sat in an empty back stairwell and showed a reporter how he tries to avoid overdosing when he smokes crack cocaine.

3 Jan 2025

Syringe exchange fears hobble fight against West Virginia HIV outbreak

More than three years have passed since federal health officials arrived in central Appalachia to assess an alarming outbreak of HIV spread mostly between people who inject opioids or methamphetamine.

3 Jan 2025

Switching to e-cigarettes may ease respiratory symptoms, offering hope for smokers

The study indicates that e-cigarettes might reduce smoking-related respiratory symptoms, yet further research is essential to understand long-term effects.

3 Jan 2025

A new blood test for endometriosis

Australian researchers develop novel test to diagnose debilitating condition affecting one in nine Australian women and girls.

3 Jan 2025

Can nicotine improve cognitive function and inflammation in people with HIV?

Research indicates smoking may improve cognitive control in HIV-positive individuals by lowering brain inflammation, highlighting nicotine's potential benefits.

3 Jan 2025

New Year, new approach to weight loss: Almost three quarters of UK women are considering using GLP-1s in 2025

As 2024 draws to a close, the new year ushers in the opportunity to set new goals for the year ahead. While weight-loss and fitness are staples of New Year resolutions they are commonly known to be the unsustainable resolutions that don't continue past January.

3 Jan 2025

Unveiling the role of gene inactivation in human disease

New work by Columbia researchers has turned a textbook principle of genetics on its head and revealed why some people who carry disease-causing genes experience no symptoms.

2 Jan 2025

Predicting H5N1 disease severity based on T cell responses

New research led by scientists at La Jolla Institute for Immunology (LJI) suggests that many people already have immune cells on "stand by" to fight the H5N1 virus, also known as highly pathogenic avian influenza.

2 Jan 2025

Polarimetry tracks Achilles tendon regeneration

Achilles tendon injuries are common but challenging to monitor during recovery due to the limitations of current imaging techniques. Researchers, led by Associate Professor Zeng Nan from the International Graduate School at Shenzhen, Tsinghua University, have applied Mueller matrix polarimetry, a non-invasive imaging method, to more accurately observe and evaluate the healing of Achilles tendon injuries.

2 Jan 2025

Study identifies novel IgAN loci through pleiotropy

IgA nephropathy (IgAN) is a prevalent form of primary glomerulonephritis characterized by the deposition of IgA in the glomerular mesangium, leading to a spectrum of histopathological lesions and a variable clinical course that can progress to end-stage renal disease in a significant proportion of patients.

2 Jan 2025

Mild avian flu cases in US spark safety warnings for poultry and dairy sectors

Researchers identify 46 mild cases of avian influenza A(H5N1) in U.S. poultry and dairy workers, highlighting low PPE adherence and potential outbreak risks.

2 Jan 2025

Scientists uncover how aging rewires the brain's molecular landscape

Scientists mapped how aging alters gene expression across brain cell types in mice, revealing immune activation, neuronal decline, and hypothalamus-specific changes that may impact aging and neurodegeneration.

2 Jan 2025

New nasal swab test for diagnosing asthma subtypes in children

Researchers at the University of Pittsburgh have developed a nasal swab test for kids that diagnoses specific asthma subtype, or endotype.

2 Jan 2025

Understanding the impact of parasocial relationships on grief and mourning

Many people are surprised by the intensity of their response when a well-known person dies, and their feelings of sadness may last longer than they expect.

2 Jan 2025

Ancient brain circuit stabilizes gaze during movement in early development

An ancient brain circuit, which enables the eyes to reflexively rotate up as the body tilts down, tunes itself early in life as an animal develops, a new study finds.

2 Jan 2025

New nanopore-based tool enables single molecule disease detection

UC Riverside scientists have developed a nanopore-based tool that could help diagnose illnesses much faster and with greater precision than current tests allow, by capturing signals from individual molecules.

2 Jan 2025

CDC study highlights growing tularemia threat in central U.S.

Tularemia cases in the U.S. rose by 56% from 2011 to 2022, with central states and American Indian communities most affected, highlighting diagnostic advancements and health disparities.

2 Jan 2025

Study provides new insights into the genetic underpinnings of pediatric cancers

Largescale changes in the genome inherited from parents are significant risk factors for pediatric solid tumors, such as Ewing sarcoma, neuroblastoma, and osteosarcoma, according to a new study.

2 Jan 2025

New immunotherapy shows long-term benefits in preventing squamous cell carcinoma

A new study by investigators from Mass General Brigham uncovers how a novel immunotherapy prevents squamous cell carcinoma, with benefits lasting five years after treatment.

2 Jan 2025

CAR-T cells carry memory of past antigen encounters

Researchers at the University of Colorado Anschutz Medical Campus have discovered that some CAR-T cells engineered to fight cancer and other conditions carry the memory of past encounters with bacteria, viruses and other antigens within them, a finding that may allow scientists to manufacture the cells in more precise and targeted ways.

2 Jan 2025