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‘Junk food’ plant diets raise heart risk even if meat is cut out

Research shows that healthy plant-based diets lower cardiac biomarkers, while unhealthy plant foods raise heart disease risk. Key findings from a large study.

11 Jun 2025

Enhanced Genomics appoints Dietrich Stephan, Ph.D. as Chair of the Board to lead ambitious growth strategy

Enhanced Genomics (‘Enhanced’ or ‘the Company’), the biotechnology company pioneering 3D multi-omics to rapidly identify high-confidence, genetically validated drug targets for common diseases, today announced the appointment of Dietrich Stephan, Ph.D. as Chair of the Board of Directors.

11 Jun 2025

Maternal iron deficiency disrupts embryonic sex determination in mice

Developmentally expressed genes play a fundamental role in the formation of a wide range of organs. The Y chromosome-located mammalian sex-determining gene Sry, required for the formation of testis, is activated only within a narrow time window during embryogenesis.

11 Jun 2025

CHAF1B drives lung squamous cell carcinoma progression by repressing SETD7

CHAF1B, a histone chaperone component of the chromatin assembly factor-1 complex, is overexpressed in multiple cancers and linked to tumor progression, but its role in lung squamous-cell carcinoma (LUSC) remained unclear.

11 Jun 2025

Rethinking dementia through the lens of sensory changes

Memory problems have long been considered the primary hallmark of dementia, but a team of researchers is now challenging this view. They argue that changes in sensory perception – from vision to balance – may be equally important indicators that many healthcare providers are currently missing.

11 Jun 2025

AMA endorses resolution to expand access to anti-obesity medications

The American Medical Association (AMA) House of Delegates today passed the Endocrine Society's resolution to improve access to anti-obesity medications.

11 Jun 2025

Tufts researchers design new generation of weight loss medications

Weight loss drugs like Ozempic and Wegovy are used by over 15 million adults in the U.S., or 4.5% of the population. Despite their effectiveness, they have drawbacks.

11 Jun 2025

Targeting metabolic reprogramming in breast cancer treatment

Breast cancer remains the most prevalent malignancy among women worldwide, posing a critical challenge to global health.

11 Jun 2025

John Oldham redefines the landscape of personality disorders

In a comprehensive Genomic Press Interview published today in Brain Medicine, John M. Oldham, MD, MS, one of psychiatry's most influential architects of personality disorder theory, traces his remarkable journey from frontier medicine roots in Oklahoma to revolutionizing how mental health professionals understand and diagnose personality pathology.

11 Jun 2025

Uncovering the genetic link between type 2 diabetes and brain structure

Type 2 diabetes mellitus (T2DM) is a highly prevalent metabolic disorder worldwide. Beyond glucose dysregulation, it exerts significant effects on the central nervous system.

11 Jun 2025

ISSCR updates guidelines for oversight and regulation of stem cell-based embryo models

The International Society for Stem Cell Research (ISSCR) Embryo Models Working Group has released updated recommendations for the oversight and regulation of stem cell-based embryo models (SCBEM), aiming to address rapid advancements and ensure responsible scientific progress.

11 Jun 2025

Modified DASH diet shows blood pressure benefits for adults with diabetes

An estimated 38.1 million adults in the United States had diagnosed diabetes in 2021, according to the Centers for Disease Control and Prevention.

11 Jun 2025

Large cohort study reassures on mRNA vaccine safety for early pregnancies

A large prospective cohort study in Germany found no statistically significant increase in major birth defects following first trimester mRNA COVID-19 vaccination. While slightly higher rates of some anomalies were observed in vaccinated pregnancies, no consistent patterns or causal links emerged.

11 Jun 2025

Italian researcher sheds light on the lasting psychiatric impact of childhood trauma

In a revealing Genomic Press Interview published today in Brain Medicine, Sara Poletti, PhD, senior researcher at IRCCS Ospedale San Raffaele Milan, illuminates the profound connections between childhood adversity and lifelong vulnerability to psychiatric disorders through persistent neuroinflammation pathways and alterations in brain structure.

11 Jun 2025

Eva1 targeted CAR T cells successfully eliminate tumors in preclinical study

CAR-T cells are specialized immune cells genetically modified to recognize and attack cancer cells. Researchers at Nagoya University in Japan and their collaborators have developed new CAR-T cells to target malignant tumors.

11 Jun 2025

Chromium-rich fiber supplement keeps you fuller and reduces insulin spikes

A single dose of a chromium-enriched glucomannan-fructo-oligosaccharide fiber complex significantly reduced postprandial insulin and increased fullness in healthy adults, without affecting blood glucose. These findings highlight the potential of this functional fiber blend to support appetite control and metabolic health.

10 Jun 2025

Scientists discover hundreds of new metabolites linked to the human microbiome

Human metabolism is a complex web of chemical processes and interactions between our cells and the microbes living within us.

10 Jun 2025

Protein ELAV identified as key regulator of circular RNAs in the brain

Deep within our nerve cells, a molecule is at work that has no beginning and no end. Instead of a straight chain, as is it common for most RNA strands, it forms a closed loop.

10 Jun 2025

Psilocybin rewires the brain for weeks, study finds

Psilocybin induces consistent and sustained changes in brain network connectivity, particularly between the hippocampus and default mode network, as shown using high-resolution fMRI in healthy adults. These neural effects, distinct from those produced by methylphenidate, may underlie the drug’s psychological benefits and were reproducible within individuals over time.

10 Jun 2025

Is it time to rethink dairy? Here’s what 25 years of research reveals for women

A 25-year Finnish cohort study found that higher intake of liquid dairy products lowers the risk of osteoporotic and general fractures in older women. Cheese consumption was specifically linked to reduced hip fracture risk, while overall fracture risk was unaffected by cheese.

10 Jun 2025