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New insights into the mechanisms of "Niemann-Pick type C" in children

In the journal "Science Translational Medicine", scientists from DZNE and LMU Hospital report on new insights into the mechanisms of "Niemann-Pick type C" (NPC), a rare neurodegenerative disease associated with dementia that can manifest as early as childhood.

6 Dec 2024

Dual-antibody therapy shows promise in treating metastatic colorectal cancer

Metastatic colorectal cancer (mCRC) remains a daunting challenge, especially after first-line treatments fail.

6 Dec 2024

Neighborhood disadvantage found to affect blood pressure and cognition

New research from Wake Forest University School of Medicine suggests that living in a disadvantaged neighborhood is associated with higher blood pressure and lower cognitive scores, even among people who do not have an existing diagnosis of mild cognitive impairment.

6 Dec 2024

New technology guides immune cells to fight brain cancer and multiple sclerosis

Researchers have found a way to program immune cells to attack glioblastoma and treat the inflammation of multiple sclerosis in mice.

6 Dec 2024

Asylum seekers in the U. S. report high levels of stress and cardiovascular disease symptoms

Many individuals seeking asylum in the United States show increased stress and pain symptoms that are associated with indications of cardiovascular disease, according to Weill Cornell Medicine researchers.

6 Dec 2024

Stubble burning in Punjab linked to health problems and high household costs

Punjab is the epicenter of stubble burning in India. Although the majority of residents are aware of the harmful effects of burning crop waste, it is still a widespread practice, with serious consequences for health, household expenditures and the environment.

6 Dec 2024

New Marie Skłodowska-Curie Doctoral Network advances AI solutions for Parkinson’s disease

Neurological disorders are now the leading cause of disability worldwide. Parkinson's disease is the second most common neurodegenerative disorder, and case numbers are growing quickly.

6 Dec 2024

New compound HPH-15 offers promising alternative to diabetes medications

Kumamoto University scientists have unveiled a novel compound, HPH-15, with dual effects of reducing blood glucose levels and combating fat accumulation, marking a significant leap in diabetes treatment innovation.

6 Dec 2024

MRI-based imaging technique predicts the response of ovarian cancer to treatment

An MRI-based imaging technique developed at the University of Cambridge predicts the response of ovarian cancer tumors to treatment, and rapidly reveals how well treatment is working, in patient-derived cell models.

6 Dec 2024

International experts set framework for microbiota diagnostics

The gut microbiota might perhaps one day become a routine tool for the early diagnosis of many diseases and to guide treatment, but at present there is a lack of solid scientific evidence to support these claims.

6 Dec 2024

Mapping blood system changes offers new hope for leukemia treatments

Researchers at University of California San Diego School of Medicine and their colleagues have developed the first comprehensive map of the dramatic changes that take place in the blood system over the course of the human lifetime.

6 Dec 2024

Study uncovers mechanism behind nutrient scavenging in pancreatic cancer

Cancer cells are like booming cities without urban planners. They expand quickly, and in doing so, the resulting tumors consume more energy and other resources than they can acquire from nearby blood vessels.

6 Dec 2024

New AI method enhances breast cancer risk prediction from mammograms

A new study from Washington University School of Medicine in St. Louis describes an innovative method of analyzing mammograms that significantly improves the accuracy of predicting the risk of breast cancer development over the following five years.

6 Dec 2024

Researchers discover new receptor in pain signaling pathway

Researchers at the NYU Pain Research Center have found a new receptor for nerve growth factor that plays an important role in pain signaling, even though it does not signal on its own, according to a study published in the Journal of Clinical Investigation.

6 Dec 2024