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Lipid molecule fuels cancer growth

Cancer cells seldom start off stealthy. Quite to the contrary, they announce their presence to the immune system by planting chemical red flags right on their membranes. Once alerted, the body's defenses can swoop in, destroying rogue cells before they can do much damage. Lying at the heart of this early warning system are lipids, fatty compounds previously seen by cancer biologists primarily as a fuel source for burgeoning tumors.

18 Sep 2024

New insights into the mechanisms of efavirenz-induced neurotoxicity

Efavirenz is an important drug for treating HIV infection, but it has negative effects that can significantly impact patients' quality of life over time. It causes neuropsychiatric disorders and neurocognitive impairment in roughly 50 percent of patients. The drug is associated with abnormal lipid levels in blood plasma, but the molecular mechanisms responsible for negative clinical observations are unknown.

18 Sep 2024

Mechanically stimulated 3D multicellular systems

To study biomechanical forces in multicellular systems, effective mechanical stimulation is an essential tool. A 3D microstructure device is developed using Two-Photon Polymerization (2PP)-based 3D printing for mimicking the human multicellular environment.

From Nanoscribe GmbH & Co. KG 18 Sep 2024

The impact of poverty on child development

After the pandemic, the gap between rich and poor has widened dramatically worldwide, and Norway and the United States are no exception. In the U.S., about one in five kids are growing up in families that struggle to afford even basic needs. In Norway, that number is around eleven percent.

18 Sep 2024

Genetic analysis challenges the idea that loneliness directly causes diseases

Research reveals that loneliness is linked to numerous diseases observationally, but genetic analysis shows it's likely a marker rather than a cause.

18 Sep 2024

Survey reveals significant gaps in global pandemic preparedness

Abbott announced the findings of a new survey; among leading infectious disease experts around the world on the state of pandemic preparedness and found that while most agree that preparation has improved since the COVID-19 pandemic, respondents say significant gaps remain in building surveillance programs to identify emerging pathogens, public health funding and having adequate testing infrastructure capabilities.

18 Sep 2024

Long COVID patients maintain robust immune memory two years after infection

Researchers discovered that SARS-CoV-2-specific T and B cells in long COVID patients are maintained for two years, similar to fully recovered individuals, offering insights into long-term immunity.

17 Sep 2024

New system improves blood thinner safety

Doctors and pharmacists treating people with blood thinners can reduce the rate of inappropriate dosing - as well as blood clots and strokes that can result from it - using an electronic patient management system, a study suggests.

17 Sep 2024

Air pollution drives higher Parkinson’s risk and worsens symptoms in affected patients

Higher air pollution levels, particularly PM2.5 and NO2, significantly increase the risk of Parkinson's disease and worsen clinical outcomes like dyskinesia.

17 Sep 2024

Innovative triplet therapy shows encouraging results in advanced chronic myeloid leukemia

According to researchers at The University of Texas MD Anderson Cancer Center, 80% of patients with previously untreated or relapsed/refractory advanced-phase chronic myeloid leukemia (CML) – including both accelerated or myeloid blast phases of the disease – or Philadelphia chromosome-positive acute myeloid leukemia (AML) achieved a bone marrow remission when treated with a novel combination of decitabine, venetoclax and ponatinib.

17 Sep 2024

Research highlights the importance of capturing social risk factors in healthcare

First-of-its-kind research by Tarang Parekh, assistant professor of epidemiology, reviewed the State Innovation Models (SIM), a payment system introduced by the Centers for Medicare and Medicaid Services in 2013, which provides financial incentives to states to develop innovative payment models to improve healthcare systems.

17 Sep 2024

Humor helps reduce avoidance of colorectal cancer information

Colorectal cancer (CRC) is no laughing matter. It's the second-leading cause of cancer deaths globally, according to the World Health Organization.

17 Sep 2024

Study uncovers ancestry-specific genetic links to multiple sclerosis risk

A landmark study has uncovered novel ancestry-specific genetic variants linked to multiple sclerosis (MS), offering new insights that could reshape treatment approaches for diverse populations affected by the disease.

17 Sep 2024

Cancer patients favor early financial risk assessments

Patients with cancer want their care team to assess them early in treatment about their concerns related to costs of care, reports a Northwestern Medicine study.

17 Sep 2024

Microplastics found in the human brain via the olfactory pathway

Researchers have identified microplastics in the human olfactory bulb, highlighting a potential pathway for these particles to enter the brain and raise concerns about their long-term neurological effects.

17 Sep 2024

Study reveals higher breast cancer mortality risk for black women across all tumor types

Breast cancer is the most diagnosed cancer among U.S. women and the second leading cause of cancer death.

17 Sep 2024

Low-dose ketamine eases fentanyl withdrawal symptoms

Drug overdose is the leading cause of injury deaths in young adults in the United States, with fentanyl causing over 70,000 deaths annually.

17 Sep 2024

Telehealth app found to improve retention rates in opioid use disorder treatment

Patients who initiated treatment for opioid use disorder through a telehealth mobile app stayed with treatment at a greater rate over six months than those who started treatment in a physical clinic, a new study led by Oregon Health & Science University found.

17 Sep 2024

UC San Diego researcher receives $21 million grant to study sensory coordination in animals

For all animals, sensory processing is a matter of survival. Sight, smell, touch, taste and hearing - the coordination of these senses together helps them find food, return to shelter and escape danger.

17 Sep 2024

Socioeconomic disparities in coronary artery disease deaths linked to unhealthy behaviors

Lower socioeconomic status is associated with higher rates of death from coronary artery disease compared to higher socioeconomic status, and more than half of the disparities can be explained by four unhealthy behaviors.

17 Sep 2024