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Weill Cornell Medicine leads $14.9 million effort to develop personalized HIV cures

A multi-institutional team led by Weill Cornell Medicine has received a five-year, $14.9 million grant from the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, to find ways to remove latent HIV from the cells of individuals with HIV.

17 Aug 2025

Nanobody breakthrough offers precise targeting of lung cancer cells

A research team led by Dr. Juyeon Jung at the Bio-Nano Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), has developed a nanobody-based technology that can precisely identify and attack only lung cancer cells, opening new possibilities for cancer therapy.

17 Aug 2025

Plasma proteomics study unlocks predictive biomarkers for TNBC immunotherapy

Triple-negative breast cancer (TNBC) is an aggressive subtype lacking targeted therapies, making immunotherapy a promising yet unpredictable option.

17 Aug 2025

New insights into how multisensory integration happens in the brain

It has long been understood that experiencing two senses simultaneously, like seeing and hearing, can lead to improved responses relative to those seen when only one sensory input is experienced by itself.

17 Aug 2025

Alzheimer’s gene risks differ by ancestry, major study reveals 133 new variants

Researchers used whole-genome sequencing from diverse populations to identify 156 variants, including 133 novel ones, linked to Alzheimer’s disease and related dementias. The study highlights ancestry-specific genetic risk and protective factors, challenging one-size-fits-all approaches to dementia genetics.

17 Aug 2025

Study shows probiotics help preterm babies fight antibiotic-resistant bacteria

Researchers found that probiotics help reduce antibiotic-resistant bacteria in the guts of very-low-birth-weight preterm infants, but cannot fully prevent resistance genes from spreading. Antibiotic use still promotes gene swapping, highlighting the limits of probiotics alone in neonatal care.

17 Aug 2025

Community pop-up screenings uncover hidden cardiovascular risk factors

Pop-up screening for atherosclerotic cardiovascular disease (ASCVD) risk held at community pharmacies and large-scale sporting events can identify people with uncontrolled cardiovascular risk factors, according to a study published in JACC, the flagship journal of the American College of Cardiology, and simultaneously presented at the 73rd Annual Scientific Meeting of the Cardiac Society of Australia and New Zealand.

17 Aug 2025

Genetically-engineered immune cells show promise for preventing organ rejection

A Medical University of South Carolina team reports in Frontiers in Immunology that it has engineered a new type of genetically modified immune cell that can precisely target and neutralize antibody-producing cells complicit in organ rejection.

17 Aug 2025

New generation of CRISPR shows safer path to treating genetic diseases

A new generation of CRISPR technology developed at UNSW Sydney offers a safer path to treating genetic diseases like Sickle Cell, while also proving beyond doubt that chemical tags on DNA - often thought to be little more than genetic cobwebs - actively silence genes.

17 Aug 2025

Portable device enables at-home monitoring of Parkinson’s disease symptoms

The number of people living with Parkinson's disease globally has doubled in the past 25 years.

17 Aug 2025

Dementia-like protein clumping found in early pancreatic cancer cells

Cancer Research UK-funded scientists have uncovered dementia-like behaviour in pancreas cells at risk of turning into cancer. The findings provide clues that could help in the treatment and prevention of pancreatic cancer, a difficult-to-treat disease linked to 6,900 deaths in the UK every year.

17 Aug 2025

Patients recall inadequate disclosure of electroconvulsive therapy risks

The medical pros of electroconvulsive therapy (ECT) are being exaggerated while the risks are being downplayed, suggest the findings of a survey on the type of information patients and their relatives/friends recall having been given before the procedure, and published online in the Journal of Medical Ethics.

17 Aug 2025

Trial finds no cardiovascular benefit and higher safety risks with spironolactone in dialysis patients

A large international study has found that spironolactone, a medication for high blood pressure and heart failure, does not reduce the risk of heart-related death or hospitalizations in people with kidney failure receiving dialysis, despite earlier smaller studies suggesting benefit.

17 Aug 2025

International experts recommend broader use of cardioprotective diabetes drugs

SGLT-2 inhibitor and GLP-1 receptor agonist drugs should be used in all or almost all adults with type 2 diabetes at higher risk of cardiovascular and kidney complications, and in the majority of adults at moderate risk of complications, say a panel of international experts in The BMJ today.

17 Aug 2025

Maryland taps Affordable Care Act fund to help pay for abortion care

Maryland is the first state to tap into an old fund connected to the Affordable Care Act to help solve a new problem: helping pay the expenses of patients who travel to Maryland for an abortion.

17 Aug 2025

Breaking down why Medicare Part D premiums are likely to go up

Medicare enrollees who buy the optional Part D drug benefit may see substantial premium price hikes — potentially up to $50 a month — when they shop for next year's coverage.

17 Aug 2025

Respiratory viruses awaken dormant breast cancer cells and raise relapse risk

Respiratory viruses such as influenza and COVID-19 can reactivate dormant breast cancer cells in the lungs, raising the risk of metastasis. The process is driven by IL-6–induced cell changes and immune suppression, with the highest recurrence risk soon after infection.

14 Aug 2025

Eating over 60g of almonds a day may protect DNA and cut oxidative damage

A meta-analysis of eight clinical trials found that almond supplementation, especially at doses above 60 g/day, significantly reduced oxidative DNA and lipid damage and improved antioxidant enzyme activity in adults. The benefits varied by biomarker and were influenced by dose, preparation, and participant characteristics.

14 Aug 2025

How moving to a walkable city can add 1,100 steps to your day

Moving to a more walkable city boosts daily step counts by around 1,100, with gains lasting at least three months and consistent across most demographic groups. Large walkability improvements nearly double the share of people meeting U.S. aerobic activity guidelines.

14 Aug 2025

GIPR signaling opens brain’s gate for GLP-1 weight-loss therapy

A Cell Metabolism study reveals that GIPR signaling in oligodendrocytes enhances brain access and weight-loss efficacy of GLP-1R agonists by increasing vascular permeability and targeting appetite-regulating neurons. This mechanism may explain why GIPR/GLP-1R co-agonists outperform single-agent therapies.

14 Aug 2025