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Autism risk genes linked to white matter changes at birth, shaping early brain development

Genetic variants linked to autism are associated with structural differences in neonatal white matter, particularly increased fiber-bundle cross-section in the left superior corona radiata, highlighting early neurodevelopmental influences.

5 Feb 2025

How olive oil bioactives regulate genes linked to insulin resistance

Olive oil bioactives, including MUFAs, polyphenols, and triterpenoids, modulate gene expression linked to insulin sensitivity, inflammation, and beta-cell function, offering potential benefits for Type 2 Diabetes Mellitus prevention and management.

5 Feb 2025

Earth is heating beyond human limits, scientists warn of deadly thresholds

As global temperatures rise, more regions are experiencing heat levels that exceed the human body's ability to cool itself. Scientists reveal how record-breaking heat waves are pushing past survival thresholds, making urgent climate action and adaptation critical.

5 Feb 2025

Research disproves persister bacteria as main cause of antibiotic resistance

Antibiotics are indispensable for treating bacterial infections. But why are they sometimes ineffective, even when the bacteria are not resistant? In their latest study published in the journal Nature, researchers from the University of Basel challenge the conventional view that a small subset of particularly resilient bacteria are responsible for the failure of antibiotic therapies.

5 Feb 2025

New nasal vaccine for COVID-19 set to begin clinical trial in the U.S.

A nasal vaccine for COVID-19 – based on technology developed at Washington University in St. Louis – is poised to enter a phase 1 clinical trial in the U.S. after an investigational new drug application from Ocugen, Inc. was approved by the Food and Drug Administration (FDA). Ocugen, a U.S.-based biotechnology company, licensed the innovative technology from WashU in 2022.

5 Feb 2025

COVID-19 speeds up artery plaque growth, raising heart disease risk

COVID-19 accelerates the progression of atherosclerotic plaques, increasing coronary inflammation and the risk of high-risk plaques, even in non-hospitalized individuals.

5 Feb 2025

Inhibiting S6K2 gene offers potential treatment for drug-resistant melanoma

The lab of The Wistar Institute's Jessie Villanueva, Ph.D., has identified a new strategy for attacking treatment-resistant melanoma: inhibiting the gene S6K2. .

5 Feb 2025

No extra benefit from mechanical clot removal over medications in some strokes

Removing a clot blocking a medium- or small-sized artery in the brain mechanically is a safe treatment for a common type of stroke; however, it did not lessen disability more than best medical treatment (including clot-busting medication if indicated) alone, according to preliminary late-breaking science presented today at the American Stroke Association's International Stroke Conference 2025.

5 Feb 2025

AI predicts effective treatment for rare disease using existing medications

After combing through 4,000 existing medications, an artificial intelligence tool helped uncover one that saved the life of a patient with idiopathic multicentric Castleman's disease (iMCD).

5 Feb 2025

Racial disparities found in migraine diagnosis for children and teens

Children and young people who are Black or Hispanic are less likely to be diagnosed with migraine than those who are white when being seen for headache in a pediatric emergency department, according to a study published in the February 5, 2025, online issue of Neurology, the medical journal of the American Academy of Neurology.

5 Feb 2025

Study suggests a possible link between trauma and endometriosis

The study is an international collaboration based on previous research that has suggested a possible connection between trauma and endometriosis.

5 Feb 2025

New medication-based approach reverses inguinal hernias in mice

By age 75, a noteworthy 50% of men develop an inguinal (groin) hernia - a bulge that results from soft tissue pushing through a weak spot in the abdominal muscles.

5 Feb 2025

Breakthrough personalized vaccine shows promising results in kidney cancer trial

Dana-Farber Cancer Institute researchers report that all nine patients in a clinical trial being treated for stage III or IV clear cell renal cell carcinoma (a form of kidney cancer), generated a successful anti-cancer immune response after initiation of a personalized cancer vaccine.

5 Feb 2025

Study could pave the way for routine eyecare imaging as a disease screening tool

Researchers have conducted one of the largest eye studies in the world to reveal new insights into retinal thickness, highlighting its potential in the early detection of diseases like type 2 diabetes, dementia and multiple sclerosis.

5 Feb 2025

California housing officials recommend state protect renters from extreme heat

Citing the hundreds of lives lost to extreme heat each year, California state housing officials are urging lawmakers to set residential cooling standards long opposed by landlords and builders who fear such a measure would force them to make big-ticket upgrades.

5 Feb 2025