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WHO reviews highlight limited long-term data on GLP-1 drug safety

Three new Cochrane reviews find evidence that GLP-1 drugs result in clinically meaningful weight loss, but industry-funded studies raise questions. The reviews were commissioned by the World Health Organization (WHO) to inform upcoming guidelines on the use of these drugs to treat obesity.

30 Oct 2025

Diets that harm the planet also raise the risk of cancer, heart disease, and diabetes

Diets that place greater pressure on the environment, high in meat and low in plant foods, were linked to higher risks of cancer, coronary heart disease, and type 2 diabetes in over 34,000 French adults. Sustainable, plant-rich diets were associated with better health and lower environmental impact.

29 Oct 2025

Diabetes remission possible with GLP-1 drugs, Italian study confirms

In a large real-world Italian cohort, GLP-1 receptor agonist therapy led to measurable rates of type 2 diabetes remission, depending on how remission was defined. The most pragmatic definition (Remission 3) was linked to improved glycemia, weight, and a lower risk of microvascular and cardiovascular events.

29 Oct 2025

Eating habits tied to Parkinson’s risk: sweets and processed meats raise odds, fruit lowers them

In a large Italian case-control study, researchers identified data-driven dietary patterns linked to Parkinson’s disease risk. Diets rich in sweets, red and cured meats were associated with higher odds of PD, while fruit, especially citrus, was protective.

29 Oct 2025

Aligning your body clock may protect your heart and metabolism, says AHA

A new American Heart Association scientific statement highlights how maintaining circadian health through regular sleep, light exposure, meal timing, and exercise may reduce cardiometabolic disease risk. Disrupting these daily rhythms can impair glucose regulation, blood pressure, and cardiovascular function.

29 Oct 2025

Scripps Research professor wins $3.2 million grant to unravel the mysteries of type 1 diabetes

Luc Teyton, professor in the Department of Immunology and Microbiology at Scripps Research, has received a five-year, $3.2 million grant from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) to help answer how type 1 diabetes manifests and develop potential therapeutics to reverse or prevent the disease.

29 Oct 2025

Rapamycin shows promise in treating cold tumors with specific gene mutation

Immune checkpoint inhibitors (ICIs) emerged in the US about 15 years ago as an exciting class of cancer treatments that have achieved complete and durable remissions for thousands of people with end-stage metastatic cancers.

29 Oct 2025

Targeting myeloid cells to enhance cancer immunotherapy

Mayo Clinic researchers have identified a specific immune cell that can be targeted to give a boost to standard immunotherapies for cancer.

29 Oct 2025

Rethinking kindergarten reading screenings for better outcomes

In most states, schools are required to screen students as they enter kindergarten - a process that is meant to identify students who may need extra help learning to read. However, a new study by MIT researchers suggests that these screenings may not be working as intended in all schools.

29 Oct 2025

Computational model predicts the hemodynamic response of patients following atrial fibrillation

Atrial fibrillation (AFib) is a cardiac disorder in which the chambers of the heart beat rapidly and irregularly. It's the most common type of arrhythmia and the leading cardiac cause of stroke.

29 Oct 2025

Systematic analysis reveals psilocybin's impact on obsessive-compulsive behaviors

A systematic review published today in Psychedelics by Mr. James Gattuso and colleagues at the Florey Institute of Neuroscience and Mental Health synthesizes clinical and preclinical evidence on psilocybin's effects on obsessive-compulsive behaviors, revealing consistent therapeutic potential across human patients and validated animal models.

29 Oct 2025

Retaining gonad function could be a potent strategy to fight late-life frailty

Frailty threatens older individuals because it increases their vulnerability to detrimental health outcomes, such as falling, longer hospitalization, or even shortened life expectancy.

29 Oct 2025

Harnessing extracellular vesicles for targeted lung cancer treatment

In the quest for more targeted lung cancer treatments, a researcher at the University of Missouri thinks the solution may lie in tiny bubble-shaped packages that cells use to talk to each other.

29 Oct 2025

New infection prevention guidance for nursing homes released

The Society for Healthcare Epidemiology of America (SHEA), in collaboration with the Association for Professionals in Infection Control and Epidemiology (APIC), the Infectious Diseases Society of America (IDSA), the Post-Acute and Long-Term Care Medical Society (PALTmed), and the American Geriatrics Society (AGS), today released Multisociety Guidance for Infection Prevention and Control in Nursing Homes.

29 Oct 2025

Unlocking memory: The role of epigenetics in memory expression

Our experiences leave traces in the brain, stored in small groups of cells called "engrams". Engrams are thought to hold the information of a memory and are reactivated when we remember, which makes them very interesting to research on memory and age- or trauma-related memory loss.

29 Oct 2025