Impel NeuroPharma announces important POD technology milestones

Impel NeuroPharma, a medical device company developing a novel drug delivery device that enables drugs to bypass the blood-brain barrier (BBB) using direct nose-to-brain delivery, today announced a set of important milestones in its drive to commercialize its POD technology.    

The key milestones announced today are:

1. Successful first-in-human pilot study of the POD technology,
2. Three (3) collaborations with leading pharmaceutical companies to pursue applications of the POD technology in three different CNS therapeutic applications, and
3. Award of a Small Business Investigational Research (SBIR) grant from the National Institutes of Health (NIH) and National Institute of Drug Abuse to evaluate a first-in-class biologic analgesic.

The results of the first-in-human study using the POD technology will be discussed at the 2012 BIO International Convention in Boston, MA on June 18-21. The study showed a 2:1 overall preference for the POD technology over conventional nasal spray devices. "This is an encouraging result which indicates the POD technology can be easily utilized in clinical research and incorporated into commercial drug-device combination products," said John Hoekman, PhD, Impel NeuroPharma's Chief Scientific Officer. "We have designed the POD device with the end user in mind. We want to ensure it is easy to use for both patients and clinical investigators."

The collaborations announced today are the direct result of Impel NeuroPharma's focus on incorporating its drug delivery technology into meaningful therapeutic initiatives of pharmaceutical companies. One of Impel NeuroPharma's current collaborations is designed to demonstrate the effectiveness of the POD technology in humans. Results from this human study will be presented this fall.

"We are extremely pleased by the response of the pharmaceutical industry to our inventive nose-to-brain delivery technology. These collaborations validate Impel NeuroPharma's technology in a wide range of therapeutic indications and CNS agents. Our goal is to collaborate with pharmaceutical companies who have CNS agents that can benefit from nose-to-brain delivery. Our next wave of projects will continue to broaden the range of therapeutic applications in which we can provide the greatest impact," stated Michael Hite, Impel NeuroPharma's Chief Executive Officer.