Bipolar disorder common in HIV patients

By Mark Cowen, Senior medwireNews Reporter

Patients with HIV are significantly more likely to have bipolar disorder than the general population, researchers report.

In a study of 200 HIV-infected patients aged between 18 and 65 years, the team found that 15% tested positive for bipolar disorder on the Mood Disorder Questionnaire (MDQ).

The MDQ is a commonly used self-report screening instrument for bipolar disorder containing 13 yes/no symptom items, and assesses the frequency and psychosocial impact of such symptoms. A positive screen for bipolar disorder requires that seven or more positive symptoms are present, with clustering within the same period, and causing moderate to severe psychosocial problems.

The researchers found no significant differences between the 30 MDQ-positive and 170 MDQ-negative patients regarding gender, age, years since HIV diagnosis, self-reported sexual orientation, and prevalence of sex and condom use with regular partners.

However, MDQ-positive patients were significantly more likely than MDQ-negative patients to have had sex with non-regular partners (90 vs 69%), infrequent condom use with nonregular sex partners (81 vs 53%), and sex with commercial partners (50 vs 14%).

MDQ-positive patients were also more likely than MDQ-negative patients to be unemployed (47 vs 27%) or retired (27 vs 11%), but were less likely to have never married (30 vs 50%).

After HIV diagnosis, sexual behavior decreased dramatically among all patients, although such decreases were greater among MDQ-positive than MDQ-negative patients.

They researchers explain that the prevalence of bipolar disorder among HIV patients in this study is around 50% higher than that in similar low-income patients without HIV attending urban clinics, and even higher than the general population rate of 2.6%.

Souza et al conclude in the Journal of Affective Disorders: "The high prevalence of MDQ-positive patients suggests that the pattern of sexual behavior among MDQ-positive patients may contribute to HIV infection."

Licensed from medwireNews with permission from Springer Healthcare Ltd. ©Springer Healthcare Ltd. All rights reserved. Neither of these parties endorse or recommend any commercial products, services, or equipment.


The opinions expressed here are the views of the writer and do not necessarily reflect the views and opinions of News Medical.
Post a new comment

While we only use edited and approved content for Azthena answers, it may on occasions provide incorrect responses. Please confirm any data provided with the related suppliers or authors. We do not provide medical advice, if you search for medical information you must always consult a medical professional before acting on any information provided.

Your questions, but not your email details will be shared with OpenAI and retained for 30 days in accordance with their privacy principles.

Please do not ask questions that use sensitive or confidential information.

Read the full Terms & Conditions.

You might also like...
Ketogenic diet improves metabolic and mental health in schizophrenia and bipolar disorder patients, study finds