Replacing a small amount of red meat with healthier foods may improve life expectancy

A new large-scale review of data on red meat consumption and mortality suggests that increasing intake of red meat, especially if it is processed, increases the risk of death from any cause. However, the researchers also found that replacing a small proportion of red meat with fish, legumes and whole grains can improve life expectancy over time.

Red and processed meats have been shown to increase the risk of cancerESB Professional | Shutterstock

It is well known that red meat consumption (beef, pork, lamb) is associated with conditions like type 2 diabetes, cardiovascular conditions (stroke and heart attack), some cancers, and earlier death.

It has also been shown that processed red meat like sausages and bacon can cause chronic obstructive pulmonary disease, hypertension and heart failure. This is partly due to ingredients like saturated fat, (which promotes atherosclerosis), high sodium and preservative content, and potential carcinogens.

The current study focused on how changes in red meat intake over a period of 8 years affected the death rates over the next 8 years, between 1986 and 2010. US consumption has reduced, but is still more than two times the average worldwide. The researchers looked at how replacing red meat with nuts, poultry or fish, whole grains or vegetables.

Does red meat reduce life expectancy?

The data was retrieved from two large studies, the Nurses' Health Study (NHS) in over 53,500 female US registered nurses between 30 and 55 years, and the Health Professionals Follow-up Study (HPFS), covering almost 28,000 male health professionals in the US, from 40 to 75 years. All had no cardiovascular illness or cancer at the beginning of the study.

Data was taken from a four-yearly food frequency questionnaire, where participants reported how many portions of each food they ate. Participants were then classified into five groups based on changes in red meat intake.

Increased red meat intake by 3.5 servings a week was linked to a 10% higher mortality in the following 8 years. If only processed meat was considered, the risk was 13% higher, compared to 9% for unprocessed red meat. Eating one more serving of processed red meat every day, on average, over 8 years, was linked to an almost 20% increase in the risk of dying from cardiovascular disease, and a 57% increase in risk of death from neurodegenerative illness, over the next 8 years.

These trends did not change with age, gender, exercise, other dietary factors, alcohol use and smoking habits. The presence of risk factors like hypertension, diabetes, and hypercholesterolemia, or fluctuations in weight, did not change the mortality risk significantly. Obese or overweight subjects had an increased risk of 6%, possibly because their overall mortality is already high at baseline compared to normal-weight people.

On the other hand, lowering the intake of red meat while replacing it with more whole grains, vegetables or animal protein like skinless poultry, fish or eggs, lowered the risk of death in both men and women. If a serving of fish was substituted for one of red meat each day, for instance, this led to a 17% reduced risk of death over the next 8 years. The trends were similar even over shorter periods of four years, and longer ones of 12 years.

In total, there were 14,000 deaths in the study period, mostly from cardiovascular disease, cancer, brain deterioration and respiratory illness. These findings were adjusted for confounding factors like age, family history and smoking, and analyzed with respect to changes in red meat intake.

What can we learn from the research?

Unfortunately, the researchers cannot conclusively say that red meat intake was the cause of higher mortality risk since the study was observational. The research was also mostly based on data from white US health professionals, which could limit the widespread applicability of the study findings. Finally, the reasons why people reduced their red meat intake were not examined.  

However, strengths of the study include the large sample size, long follow up, repeated measurement of diet and other factors, and the fact that both studies produced almost identical conclusions.

The researchers concluded:

Increases in red meat consumption, especially processed meat, were associated with a higher risk of death. Dynamic changes in red consumption is associated with health. A change in protein source or eating healthy plant based foods such as vegetables or whole grains can improve longevity.”


Zheng Y, et al., (2019). Association of changes in red meat consumption with total and cause specific mortality among US women and men: two prospective cohort studies. British Medical Journal.

Dr. Liji Thomas

Written by

Dr. Liji Thomas

Dr. Liji Thomas is an OB-GYN, who graduated from the Government Medical College, University of Calicut, Kerala, in 2001. Liji practiced as a full-time consultant in obstetrics/gynecology in a private hospital for a few years following her graduation. She has counseled hundreds of patients facing issues from pregnancy-related problems and infertility, and has been in charge of over 2,000 deliveries, striving always to achieve a normal delivery rather than operative.


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