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Dietary antigens reduce small intestine cancer by boosting immune T-cells

Study shows that dietary antigens can suppress small intestine carcinogenesis by activating T-cells through Peyer's patches. Adding bovine serum albumin (BSA) or ovalbumin (OVA) to antigen-free diets restored immune function and reduced tumor growth in mice.

22 Sep 2024

The Key Role of iPSC-Derived Microglia in Research and Drug Discovery

Dr. Tilman explains the functions of iPSC-derived microglia and their relevance to conditions like Alzheimer’s.

From Axol Bioscience Ltd 17 Sep 2024

Promising new approach to combat HIV

Researchers at Université de Montréal's affiliated hospital research center, the CRCHUM, say the discovery could help lessen and even eliminate viral loads in people undergoing antiretroviral therapy.

11 Sep 2024

Researchers uncover mechanism fueling prostate cancer

Researchers at the University of Michigan Health Rogel Cancer Center have uncovered a key reason why a typically normal protein goes awry and fuels cancer.

9 Sep 2024

Study reveals how sex hormones regulate immune system functions

Findings indicate that testosterone therapy in trans men alters immune system responses, suggesting implications for disease susceptibility and treatment.

6 Sep 2024

Study links monoclonal B-cell lymphocytosis to elevated melanoma risk

About 8 to 10 million Americans over age 40 have an overabundance of cloned white blood cells, or lymphocytes, that hamper their immune systems.

5 Sep 2024

The role of HPV in male fertility: New data on sperm quality and oxidative stress

Findings indicate HR-HPV infections affect sperm health, increasing oxidative stress and altering cytokine levels, emphasizing HPV's impact on male fertility.

27 Aug 2024

Engineered human cardiac tissue reveals how lupus autoantibodies damage the heart

Study demonstrates that autoantibodies in systemic lupus erythematosus (SLE) patients contribute to myocardial injury by binding to and impairing stressed cardiac cells, offering insights into potential therapeutic targets.

25 Aug 2024

New $5.8 million grant aims to transform the global landscape of TB research

A $5.8 million grant led by Adrie Steyn, Ph.D., of the University of Alabama at Birmingham and the Africa Health Research Institute, or AHRI, in Durban, South Africa, will provide user-requested infected human lung tissue and analytical services to tuberculosis researchers worldwide.

23 Aug 2024

Cytek® Biosciences automates panel design with new intelligent algorithm

With the SpectroPanel tool, Cytek Cloud transforms flow cytometry panel design, enabling rapid optimization and enhancing research capabilities for scientists.

From Cytek Biosciences 23 Aug 2024

Potential antitumoral effects of Manuka honey in breast cancer models

Researchers evaluated the antitumor activity of Manuka honey on human breast cancer cells and its underlying molecular mechanisms in both in vitro and in vivo preclinical models.

22 Aug 2024

Understanding the complexities of epigenetic aging clocks in health research

A new editorial was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science), Volume 16, Issue 14 on July 17, 2024, entitled, "Recalibrate concepts of epigenetic aging clocks in human health."

14 Aug 2024

New antibody treatment shows promise in preventing heart transplant rejection

A new study from scientists at Cincinnati Children's suggests there may be a way to further protect transplanted hearts from rejection by preparing the donor organ and the recipient with an anti-inflammatory antibody treatment before surgery occurs.

12 Aug 2024

Novel molecular signaling pathway found to play a crucial role in maintaining the skin barrier

Our skin–the body's largest organ–provides the first line of defense against infections and many other threats to our health.

9 Aug 2024

New target identified for melanoma resistant to current therapies

Some proteins, such as programmed cell death protein 1 (PD1), can stop the immune system from attacking cancer cells and, therefore, support the growth of cancer.

6 Aug 2024

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

In this interview conducted at Pittcon 2024, we spoke to Professor John Yates about capturing cardiomyocyte cell-to-cell heterogeneity via shotgun top-down proteomics.

From Pittcon 6 Aug 2024