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Four months of multi-drug therapy for tuberculosis is as effective as standard regimen

Four months of multi-drug therapy that included rifapentine and moxifloxacin treated active tuberculosis (TB) as effectively as the standard six-month regimen in a multinational study, cutting treatment time by a third.

20 May 2021

Human monoclonal antibodies neutralize SARS-CoV-2 in an Fc-independent manner

Researchers from Israel recently isolated a set of SARS-CoV-2 neutralizing monoclonal antibodies from blood samples of patients with severe COVID-19. They were the first to show that transgenic K18-hACE2 mice infected with lethal doses of SARS-CoV-2 can be fully protected by administering antibodies even 3 days after infection

19 May 2021

Milder COVID-19 in children may be due to higher memory B cells responses to SARS-CoV-2

A new research paper published in the journal Science explores the differences in coronavirus-specific B memory cell repertoires in children versus adults, as well as the functional importance of this discovery.

18 May 2021

Nanotechnology and COVID-19 diagnosis and treatment

The development of nano-biosensors and nanoparticle-based vaccines and medicines has opened a new path toward better management of the coronavirus disease 2019 (COVID-19) pandemic. In a recently published article in the journal ACS Biomaterials Science & Engineering, scientists have reviewed recent advancements in nanotechnology-based diagnostic and therapeutic interventions against human coronaviruses.

17 May 2021

Unique pre-clinical model enables study of HIV infection and testing of new therapies

A team led by researchers at Weill Cornell Medicine and Children's National Hospital has developed a unique pre-clinical model that enables the study of long-term HIV infection, and the testing of new therapies aimed at curing the disease.

14 May 2021

New app focuses on supporting patients with life-limiting illnesses in Ethiopia

The Ayzot app is a collaboration between Surrey, the University of Strathclyde, Hospice Ethiopia, the Federal Ministry of Health and Hello Doctor Ethiopia, an Ethiopian-based software company run by Dr Yohans Wodaje.

13 May 2021

Study reports new monoclonal antibodies with broad neutralizing capabilities against betacoronaviruses (including SARS-CoV-2)

In a paper published on the bioRxiv* preprint server, researchers report new monoclonal antibodies that target the S2 subunit and that have broad neutralization activity against several betacoronaviruses.

13 May 2021

Black fungus complicates India's COVID pandemic

India faces a global health crisis as the number of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections reaches over 23.7 million. As India's health system buckles with increased admissions and a lack of resources, another health threat has emerged.

13 May 2021

New drug-like compound could effectively block a critical step in malaria parasite life cycle

Researchers at the Francis Crick Institute and the Latvian Institute of Organic Synthesis have designed a drug-like compound which effectively blocks a critical step in the malaria parasite life cycle and are working to develop this compound into a potential first of its kind malaria treatment.

12 May 2021

HIV patients are more likely to die from COVID-19 infection

Over the past year, studies have revealed that certain pre-existing conditions, such as cancer, diabetes and high blood pressure, can increase a person's risk of dying from COVID-19.

12 May 2021

Evolutionary-spreading model predicts another devastating COVID-19 peak around July 2021

The emergence of this variant highlighted the uneven pace of mutation and selection of variants. New bioinformatics tools are the need of the hour to clarify this and confirm a dynamic evolution by tracking the mutation rates of the spike protein. It generally takes 1 – 6 months for current variants causing COVID-19 case peaks and deaths to survive the pressure of selection.

11 May 2021

New approach targeting viral RNA could lead to broad spectrum anti-viral drugs

A new approach to tackling viruses by targeting the 'control center' in viral RNA could lead to broad spectrum anti-viral drugs and provide a first line of defense against future pandemics, according to new research at the University of Birmingham.

11 May 2021

Natural products a rich source for novel antiviral compounds

In a recent review in the journal Viruses, researchers look at natural products that can be identified as potential alternative antiviral agents. The reviewers discussed the antiviral activities of several natural products towards DNA and RNA viruses with an analytical approach. The researchers detailed the cellular/viral targets of the active molecules and their impact on the infection and viral replication cycle.

10 May 2021

Study: Novavax Covid-19 vaccine is efficacious against the B.1.351 South African variant

The published data provide additional detail of an initial analysis conducted in January, while more robust data from a complete analysis of the study was subsequently shared in March 2021.

6 May 2021

SARS-CoV-2 is activated for fusion by a broad range of proteases, finds study

A team of researchers from the University of Virginia, USA, used single-virus fusion experiments with exogenously controlled proteases to investigate the mechanism of activation directly. They found that the subcellular location of entry depends on the protease activity of the various components, and parallel pathways are possible.

6 May 2021

Telemedicine is a tool — not a replacement for your doctor’s touch

Earlier in the pandemic it was vital to see doctors over platforms like Zoom or FaceTime when in-person appointments posed risks of coronavirus exposure. Insurers were forced — often for the first time — to reimburse for all sorts of virtual medical visits and generally at the same price as in-person consultations.

6 May 2021

HIV News and Research

Four months of multi-drug therapy for tuberculosis is as effective as standard regimen

Human monoclonal antibodies neutralize SARS-CoV-2 in an Fc-independent manner

Milder COVID-19 in children may be due to higher memory B cells responses to SARS-CoV-2

Nanotechnology and COVID-19 diagnosis and treatment

Unique pre-clinical model enables study of HIV infection and testing of new therapies

New app focuses on supporting patients with life-limiting illnesses in Ethiopia

Study reports new monoclonal antibodies with broad neutralizing capabilities against betacoronaviruses (including SARS-CoV-2)

Black fungus complicates India's COVID pandemic

New drug-like compound could effectively block a critical step in malaria parasite life cycle

HIV patients are more likely to die from COVID-19 infection

Evolutionary-spreading model predicts another devastating COVID-19 peak around July 2021

New approach targeting viral RNA could lead to broad spectrum anti-viral drugs

Natural products a rich source for novel antiviral compounds

Study: Novavax Covid-19 vaccine is efficacious against the B.1.351 South African variant

SARS-CoV-2 is activated for fusion by a broad range of proteases, finds study

Telemedicine is a tool — not a replacement for your doctor’s touch

Repurposing an existing, cheap drug into long-acting injectable therapy to treat Covid-19

New $10.7 million project aims to study the genetic underpinnings of Alzheimer's disease

Certain parts of the innate immune response can be trained in response to HIV

Stem cell therapy for COVID-19 and ARDS

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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