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USC scientists develop first all-human brain organoids model of the cerebellum with functional neurons

In a first for USC Stem Cell scientists, the laboratory of Giorgia Quadrato, an assistant professor of stem cell biology and regenerative medicine, has pioneered a novel human brain organoid model that generates all the major cell types of the cerebellum, a hindbrain region predominantly made up of two cell types necessary for movement, cognition, and emotion: granule cells and Purkinje neurons.

4 Jan 2024

GLP-1R agonist liraglutide rapidly improves insulin sensitivity in pre-diabetics, independent of weight loss

A new study published in the journal Diabetes demonstrates that a glucagon-like peptide-1 receptor (GLP-1R) agonist, a member of a class of medication used to treat Type 2 diabetes and obesity, can lead to a rapid improvement in insulin sensitivity.

4 Jan 2024

Scientists unearth dual-action weapons against deadly tuberculosis

A research team has detected various substances that have a dual effect against tuberculosis: They make the bacteria causing the disease less pathogenic for human immune cells and boost the activity of conventional antibiotics / publication in ‘Cell Chemical Biology’.

4 Jan 2024

New study highlights the work of biobank at the Colorado Center for Personalized Medicine

A new peer-reviewed study in the American Journal of Human Genetics highlights the work of the biobank at the Colorado Center for Personalized Medicine (CCPM), a world-class site for precision medicine in research and clinical care created in partnership with the University of Colorado Anschutz Medical Campus and UCHealth.

4 Jan 2024

Novel population health tool for predicting ICU survivorship and mortality in older adults

A significant obstacle to improving care and outcomes for intensive care unit (ICU) patients is the unexpected nature of becoming seriously ill.

4 Jan 2024

Gonorrhea cases surge 64% post-COVID lockdown in England, highlighting unintended STI suppression

A study analyzing data from the Genitourinary Medicine Clinic Activity Dataset in England shows a 64% increase in gonorrhea diagnoses following the relaxation of COVID-19 restrictions, despite only a 5.6% increase in STI testing, suggesting that social distancing may have suppressed STI transmission.

4 Jan 2024

Metabolically armored CAR-T cells demonstrate lasting efficacy against solid tumors

At EPFL's School of Engineering, Professor Li Tang's Laboratory of Biomaterials for Immunoengineering has made significant strides in cancer treatment research.

4 Jan 2024

Researchers harness the power of AI to enhance assessment of the heart's right ventricle

In a milestone study, researchers from the Icahn School of Medicine at Mount Sinai have harnessed the power of artificial intelligence (AI) to enhance the assessment of the heart's right ventricle, which sends blood to the lungs.

4 Jan 2024

Computerized cognitive training shows promise in enhancing memory for dementia patients

Study systematically reviews and meta-analyzes the impact of computerized cognitive training (CCT) on memory functions in patients with mild cognitive impairment or dementia, highlighting the benefits of both supervised and unsupervised CCT.

4 Jan 2024

Maternal stress during preconception associated with higher blood glucose levels, study finds

Stress during pregnancy is known to influence health outcomes, but a new study from Mass General Brigham researchers suggests that stress levels before pregnancy are also important to evaluate.

4 Jan 2024

Urban green and blue spaces linked to improved mental, physical health in older adults

.Even small differences in the availability of urban green and blue spaces may be associated with better mental and physical health in older adults, according to a Washington State University study.

4 Jan 2024

Paxlovid does not reduce long COVID risk in vaccinated individuals, study finds

A team of researchers from UC San Francisco has found that Paxlovid (Nirmatrelvir-ritonavir) did not reduce the risk of developing long COVID for vaccinated, non-hospitalized individuals during their first COVID-19 infection.

4 Jan 2024

Imbalances in folic acid and vitamin B12 can alter brain development in mice

Folate is a B vitamin and a necessary nutrient to prevent neural tube defects, such as spina bifida. Folic acid, a synthetic form of folate, has been added to vitamins, breakfast cereals and other products in the U.S. and more than 80 other countries to ensure pregnant women get adequate amounts.

4 Jan 2024

Research identifies genetic connection between anorexia and morning chronotype

New research indicates that the eating disorder anorexia nervosa is associated with being an early riser, unlike many other disorders that tend to be evening-based such as depression, binge eating disorder and schizophrenia.

4 Jan 2024

Gut microbes revealed as key players in liver disease solutions

In the editorial published on 4 September 2023, in the "gut-liver axis" special issue of the journal Hepatobiliary & Pancreatic Diseases International, Dr. Jian-Gao Fan and Dr. Lu Jiang from Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine provided a comprehensive elucidation of the pivotal role of gut microbiota in various liver diseases.

4 Jan 2024

AI could revolutionize ambulance care by providing real-time patient assessment

Assessing how seriously injured a person is, involves weighing up lots of different parameters fast. If healthcare professionals could get support making fast-paced, life-critical decisions from an AI tool, more lives could be saved.

4 Jan 2024

Unmasking the persistent threats of long-COVID's pulmonary sequelae

A collaborative study led by Dr. Estefanía Nova-Lamperti of the Universidad de Concepción, Dr. Gonzalo Labarca of Harvard University, and Mauricio Hernández, of MELISA Institute, and which included the participation of researchers from leading academic institutions, sought to identify the sequelae associated with long-term pulmonary dysfunction (L-PDD) in patients with COVID-19.

4 Jan 2024

CLivD score shows promise in early detection of steatotic liver disease and advanced fibrosis

Chronic liver disease, a growing threat to global health, often progresses silently in its early stages.

4 Jan 2024

Study identifies mitochondrial dysfunction as cause of long-COVID fatigue

Researchers from Amsterdam UMC and Vrije Universiteit Amsterdam (VU) have discovered that the persistent fatigue in patients with long-COVID has a biological cause, namely mitochondria in muscle cells that produce less energy than in healthy patients.

4 Jan 2024

Stanford Medicine researchers demonstrate new way to temporarily heighten hypnotizablity

How deeply someone can be hypnotized -; known as hypnotizability -; appears to be a stable trait that changes little throughout adulthood, much like personality and IQ.

4 Jan 2024

Medicine News and Research

USC scientists develop first all-human brain organoids model of the cerebellum with functional neurons

GLP-1R agonist liraglutide rapidly improves insulin sensitivity in pre-diabetics, independent of weight loss

Scientists unearth dual-action weapons against deadly tuberculosis

New study highlights the work of biobank at the Colorado Center for Personalized Medicine

Novel population health tool for predicting ICU survivorship and mortality in older adults

Gonorrhea cases surge 64% post-COVID lockdown in England, highlighting unintended STI suppression

Metabolically armored CAR-T cells demonstrate lasting efficacy against solid tumors

Researchers harness the power of AI to enhance assessment of the heart's right ventricle

Computerized cognitive training shows promise in enhancing memory for dementia patients

Maternal stress during preconception associated with higher blood glucose levels, study finds

Urban green and blue spaces linked to improved mental, physical health in older adults

Paxlovid does not reduce long COVID risk in vaccinated individuals, study finds

Imbalances in folic acid and vitamin B12 can alter brain development in mice

Research identifies genetic connection between anorexia and morning chronotype

Gut microbes revealed as key players in liver disease solutions

AI could revolutionize ambulance care by providing real-time patient assessment

Unmasking the persistent threats of long-COVID's pulmonary sequelae

CLivD score shows promise in early detection of steatotic liver disease and advanced fibrosis

Study identifies mitochondrial dysfunction as cause of long-COVID fatigue

Stanford Medicine researchers demonstrate new way to temporarily heighten hypnotizablity

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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