Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Oral GLP-1 pill shows strong weight loss and blood sugar benefits in adults with diabetes

A new oral GLP-1 medication can help adults with obesity and Type 2 diabetes lose more weight and improve their blood sugar levels compared to a placebo, according to findings from the ATTAIN-2 trial led by a UTHealth Houston researcher.

20 Nov 2025

Changes in brain fats play a key role in Alzheimer's development and progression

More than a century ago, Alois Alzheimer noted unusual changes in brain fats, which he described as "lipoid granules," along with the buildup of amyloid-beta (amyloid) plaques and tau protein tangles.

20 Nov 2025

New fluorescent sensor allows scientists to watch DNA damage and repair in real time

Cancer research, drug safety testing and ageing biology may all gain a major boost from a new fluorescent sensor developed at Utrecht University.

20 Nov 2025

UK Biobank releases the world’s largest metabolomic dataset for disease research

UK Biobank has today [Thursday 20 November] released the final set of data on nearly 250 metabolites – the molecules in our blood produced by our bodies as we go about our lives – in half a million volunteers.

20 Nov 2025

Study compares GLP-1 drug benefits and finds substantial variation in clinical effects

GLP-1 receptor agonists improve glycaemic control and provide renal, metabolic, and selective cardiovascular benefits in people with type 2 diabetes, based on an umbrella review of 17 meta-analyses. However, these agents consistently increase gastrointestinal adverse effects and show important distinctions between class-level outcomes and individual drug effects, particularly for semaglutide.

20 Nov 2025

Engineered CAR-T cells show promise against glioblastoma in preclinical models

With a five-year survival rate of less than 5%, glioblastoma is one of the most aggressive types of brain cancer.

20 Nov 2025

Study reveals how aging reshapes protein chemistry in the brain

A study by the Leibniz Institute on Aging - Fritz Lipmann Institute (FLI) in Jena shows that the chemical composition of proteins in the brain undergoes fundamental changes with aging.

20 Nov 2025

Innovative new tool helps understand how gut microbes interact to influence health

The gut microbiome is made up of trillions of microbes that play a vital role in keeping us healthy.  A disturbance in the balance of these microbes can contribute to a variety of health conditions, such as inflammatory bowel disease (IBD).

20 Nov 2025

Study uncovers promising therapeutic strategies against neuroendocrine prostate cancer

A new study has uncovered promising therapeutic strategies against one of the deadliest forms of prostate cancer.

20 Nov 2025

Study shows how ketogenic eating improves hormonal balance in PCOS

The very low-carbohydrate ketogenic diet leads to meaningful reductions in weight, visceral adiposity, insulin resistance, and androgen excess in women with PCOS based on pooled randomized trials. Benefits appear consistent across studies, though high heterogeneity, short durations, and limited safety data highlight the need for longer-term comparative research.

19 Nov 2025

Global experts map out the practical steps that help extend life expectancy

The 1st World Longevity Summit in Kyotango, Japan brought together global experts to share advances in aging biology, lifestyle medicine, and community-based strategies for healthy longevity. Its joint declaration identified four pillars – social connection, plant-based diets, daily activity, and gratitude with purpose – as core foundations for extending healthy life expectancy worldwide.

19 Nov 2025

Cryo-EM reveals how proteins are protected during synthesis

Proteins are often called the building blocks of cells, but even those building blocks need to be built. One of the most important steps in the process of building proteins is glycosylation, when sugar molecules (glycans) are attached to the maturing protein.

19 Nov 2025

Cancer cells hijack cell death enzyme to regrow after treatment

The emergence of cancer drug resistance remains one of the most pressing problems in cancer care and there is a critical need to devise approaches to mitigate it.

19 Nov 2025

Current genetic screening guidelines overlook most cases of familial hypercholesterolemia

Current genetic screening guidelines fail to identify most people with an inherited condition known as familial hypercholesterolemia that can cause dangerously high cholesterol and early heart disease, a Mayo Clinic study found.

19 Nov 2025

Experts call for bold policies to curb the health harms of ultra-processed foods

The increase of UPFs in diets worldwide presents an urgent challenge to health that demands coordinated policies and advocacy action to address, says a new three paper Series authored by 43 global experts and published in The Lancet. The Series exposes the tactics UPF companies use to drive consumption and prevent effective policy.

18 Nov 2025

New antibody strategy shows promise for halting cyst growth in polycystic kidney disease

Polycystic kidney disease (PKD) is a debilitating hereditary condition in which fluid-filled sacs form and proliferate in the kidneys. Over time, the painful, growing cysts rob the organs of their function, often leading to dialysis in advanced cases.

18 Nov 2025

Protein News and Research

Further Reading

Oral GLP-1 pill shows strong weight loss and blood sugar benefits in adults with diabetes

Changes in brain fats play a key role in Alzheimer's development and progression

New fluorescent sensor allows scientists to watch DNA damage and repair in real time

UK Biobank releases the world’s largest metabolomic dataset for disease research

Study compares GLP-1 drug benefits and finds substantial variation in clinical effects

Engineered CAR-T cells show promise against glioblastoma in preclinical models

Study reveals how aging reshapes protein chemistry in the brain

Innovative new tool helps understand how gut microbes interact to influence health

Study uncovers promising therapeutic strategies against neuroendocrine prostate cancer

Study shows how ketogenic eating improves hormonal balance in PCOS

Global experts map out the practical steps that help extend life expectancy

Cryo-EM reveals how proteins are protected during synthesis

Cancer cells hijack cell death enzyme to regrow after treatment

Current genetic screening guidelines overlook most cases of familial hypercholesterolemia

Experts call for bold policies to curb the health harms of ultra-processed foods

New antibody strategy shows promise for halting cyst growth in polycystic kidney disease

New AI investment aims to accelerate the search for an effective HIV vaccine

DeepTarget tool uncovers primary and secondary drug targets across cancer types

Novel therapy reduces tumor growth in models of triple-negative breast cancer

Study reveals how gestational diabetes disrupts the placenta at the molecular level

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