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Mount Sinai study provides a mechanistic explanation for variations in individual responses to drugs

Mount Sinai researchers have shown for the first time that a person's beliefs related to drugs can influence their own brain activity and behavioral responses in a way comparable to the dose-dependent effects of pharmacology.

3 Jan 2024

AI-generated images promise to transform medical diagnostics

Diagnosing cancer today involves using chemical "contrast agents" to improve the accuracy of medical imaging processes such as X-rays as well as computed tomography (CT) and magnetic resonance imaging (MRI) scans.

3 Jan 2024

Yale scientists identify drug target that may alleviate joint degeneration in osteoarthritis

Yale researchers have identified a drug target that may alleviate joint degeneration associated with osteoarthritis, a debilitating condition that afflicts as many as 30 million people in the United States alone, which they report on Jan. 3 in the journal Nature.

3 Jan 2024

Existing beta blocker investigated as novel sickle cell therapy

A beta blocker typically used to treat heart problems, hemangioma, migraines and anxiety could be a new therapeutic for patients with sickle cell disease. Researchers led by Ankit A. Desai, MD, associate professor of medicine at the Krannert Cardiovascular Research Center (KCVRC) at Indiana University School of Medicine, have been awarded a $3 million grant by the U.S. Department of Defense to evaluate the efficacy of this drug.

3 Jan 2024

New research project seeks to find innovative treatment pathways for Type 2 diabetes and obesity

A team of Virginia Tech researchers was awarded nearly $2 million from the National Institute of Diabetes and Digestive and Kidney Disease, part of the National Institutes of Health, to explore novel approaches for treating Type 2 diabetes and obesity.

3 Jan 2024

"Genetic priority score" promises to revolutionize drug development

Driven by the need for a better way to prioritize targets for drug development, the Icahn School of Medicine at Mount Sinai has led the development of a novel "genetic priority score" (GPS) that will integrate various types of human genetic data into a single easy-to-interpret score.

3 Jan 2024

Researchers identify microbial enzyme responsible for making urine yellow

Researchers at the University of Maryland and National Institutes of Health have identified the microbial enzyme responsible for giving urine its yellow hue, according to a new study published in the journal Nature Microbiology on January 3, 2024.

3 Jan 2024

Artificial intelligence is a promising tool to disseminate nutrition-related information, study finds

The accuracy and reliability of nutrition information provided by two versions of ChatGPT.

3 Jan 2024

Patients with narcolepsy face a dual nightmare of medication shortages and stigma

Nina Shand couldn't stay awake. She had taken afternoon naps since she was a teenager to accommodate her "work hard, play hard" attitude, but when she was in her mid-20s the sleepiness became more severe.

3 Jan 2024

AI Integration in the Fight Against Age-Related Macular Degeneration

In this interview, Wen Hwa Lee, CEO, and Chief Scientist at Action Against Age-Related Macular Degeneration (AAAMD), offers an enlightening perspective on merging AI with ophthalmology to forge new paths in healthcare and drug discovery.

From ELRIG (UK) Ltd. 3 Jan 2024

Living alone? Adopting a pet might help slow cognitive decline among older adults

Researchers investigated the association between pet ownership and cognitive decline in the elderly.

3 Jan 2024

Previously unidentified protein variant shields against Parkinson's disease

A previously unidentified genetic mutation in a small protein provides significant protection against Parkinson's disease and offers a new direction for exploring potential treatments, according to a new USC Leonard Davis School of Gerontology study.

2 Jan 2024

New AI tool spotlights hidden cancers for better diagnosis

A new artificial intelligence tool that interprets medical images with unprecedented clarity does so in a way that could allow time-strapped clinicians to dedicate their attention to critical aspects of disease diagnosis and image interpretation.

2 Jan 2024

Healthy aging modulates the neural oscillatory dynamics serving working memory function

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 24, entitled, "Age-related alterations in the oscillatory dynamics serving verbal working memory processing."

2 Jan 2024

68Ga-FAPI PET imaging superior to existing methods for detecting pancreatic cancer

PET imaging with 68Ga-FAPI can more effectively detect and stage pancreatic cancer as compared with 18F-FDG imaging or contrast-enhanced CT, according to new research published in the December issue of The Journal of Nuclear Medicine.

2 Jan 2024

Scripps scientists develop powerful method to find drug targets in live cells

Identifying new ways to target proteins involved in human diseases is a priority for many researchers around the world.

2 Jan 2024

Novel PET tracer accurately detects common cancer mutation for tailored treatment

A novel PET imaging tracer has been proven to safely and effectively detect a common cancer gene mutation that is an important molecular marker for tumor-targeted therapy.

2 Jan 2024

Understanding acylspermidines' secrets could lead to treatments for various diseases

In a significant advancement in the field of biochemistry, scientists at the Boyce Thompson Institute (BTI) and Cornell University have uncovered new insights into a family of metabolites, acylspermidines, that could change how we understand aging and fight diseases.

2 Jan 2024

Brain receptor discovery opens door to new therapies for addiction and mental health

Researchers at the Icahn School of Medicine at Mount Sinai have uncovered insights into the potential mechanism of action of the antipsychotic medication asenapine, a possible therapeutic target for substance use and neuropsychiatric disorders.

2 Jan 2024

Enlarged perivascular spaces in infancy associated with sleep problems and autism risk

Throughout the day and night, cerebrospinal fluid (CSF) pulses through small fluid-filled channels surrounding blood vessels in the brain, called perivascular spaces, to flush out neuroinflammation and other neurological waste.

2 Jan 2024

Medicine News and Research

Mount Sinai study provides a mechanistic explanation for variations in individual responses to drugs

AI-generated images promise to transform medical diagnostics

Yale scientists identify drug target that may alleviate joint degeneration in osteoarthritis

Existing beta blocker investigated as novel sickle cell therapy

New research project seeks to find innovative treatment pathways for Type 2 diabetes and obesity

"Genetic priority score" promises to revolutionize drug development

Researchers identify microbial enzyme responsible for making urine yellow

Artificial intelligence is a promising tool to disseminate nutrition-related information, study finds

Patients with narcolepsy face a dual nightmare of medication shortages and stigma

AI Integration in the Fight Against Age-Related Macular Degeneration

Living alone? Adopting a pet might help slow cognitive decline among older adults

Previously unidentified protein variant shields against Parkinson's disease

New AI tool spotlights hidden cancers for better diagnosis

Healthy aging modulates the neural oscillatory dynamics serving working memory function

68Ga-FAPI PET imaging superior to existing methods for detecting pancreatic cancer

Scripps scientists develop powerful method to find drug targets in live cells

Novel PET tracer accurately detects common cancer mutation for tailored treatment

Understanding acylspermidines' secrets could lead to treatments for various diseases

Brain receptor discovery opens door to new therapies for addiction and mental health

Enlarged perivascular spaces in infancy associated with sleep problems and autism risk

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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