Efficacy News and Research

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New glucose-sensitive insulin NNC2215 could transform diabetes care by lowering hypoglycemia risk

NNC2215, a glucose-sensitive insulin, offers improved glycemic control by dynamically adjusting to blood sugar levels, reducing hypoglycemia in diabetes care.

18 Oct 2024

Novel method boosts MSC efficacy for articular cartilage repair

Researchers from the Critical Analytics for Manufacturing Personalized-Medicine (CAMP) Interdisciplinary Research Group (IRG) at Singapore-MIT Alliance for Research and Technology (SMART), MIT’s research enterprise in Singapore, alongside collaborators from the National University of Singapore Tissue Engineering Programme (NUSTEP), have developed a novel method to enhance the ability of mesenchymal stromal cells (MSCs) to generate cartilage tissue by adding ascorbic acid (AA) during MSC expansion.

18 Oct 2024

New combination treatment authorized for unresectable urothelial cancer patients

Astellas Pharma Ltd. today announced that the Medicines and Healthcare products Regulatory Agency (MHRA) has granted authorization for PADCEV™ (enfortumab vedotin, an antibody-drug conjugate [ADC]) in combination with KEYTRUDA® (pembrolizumab, a PD-1 inhibitor) for the first-line treatment of adult patients with unresectable or metastatic urothelial cancer, who are eligible for platinum-containing chemotherapy.

18 Oct 2024

Sapio Sciences enhances lab informatics platform with new immunogenicity bioanalysis features

Sapio Sciences, the science-aware™ lab informatics platform, today announced the addition of new immunogenicity bioanalysis features to its industry-leading lab informatics platform.

18 Oct 2024

Researchers uncover the potential of JAK inhibitors to treat life-threatening skin disease

Researchers identified Janus kinase inhibitors as a promising treatment for the severe drug-induced skin condition toxic epidermal necrolysis, by analyzing patient biopsies with deep visual proteomics.

17 Oct 2024

Edaravone shows promise in targeting brain tumor stem cells

Glioblastomas are aggressive brain tumors with a median survival time of less than 22 months despite standard therapy including surgery, irradiation, and chemotherapy.

17 Oct 2024

New grant aims to transform treatment for liver cancer

Currently, there are a few available treatment options for liver cancer, including a combination of immunotherapies and a class of drugs known as tyrosine kinase inhibitors (TKIs), but their long-term effects are limited.

17 Oct 2024

Trial evaluates monoclonal antibodies for long COVID prevention

The first randomized, placebo-controlled clinical trial evaluating the impact of therapeutic monoclonal antibodies on the risk of developing long COVID was led by researchers at Weill Cornell Medicine.

17 Oct 2024

FDA strengthens AI regulation to ensure patient safety and innovation in healthcare

The FDA is adapting regulations to manage AI’s rapid development in healthcare, focusing on patient safety and the life cycle of AI tools. This review emphasizes the need for continuous monitoring to ensure AI performs effectively in clinical settings.

16 Oct 2024

Expanding access to GLP-1 weight-loss drugs could save thousands of lives

Researchers estimate that expanding access to weight-loss drugs could save over 50,000 lives annually, reducing obesity rates and addressing health inequities. Current drug uptake levels prevent far fewer deaths.

16 Oct 2024

Groundbreaking antimicrobial bandage offers rapid hemostasis in accidents

Without proper medical invention, injuries sustained from traffic collisions, serious workplace accidents or weapons may result in fatal hemorrhaging.

16 Oct 2024

Clot-busting drug tenecteplase shows promising results for stroke recovery

For people with ischemic stroke, treatment with the clot-busting drug tenecteplase is associated with a slightly higher likelihood of an excellent recovery and reduced disability three months later than the drug alteplase, according to a meta-analysis published in the October 16, 2024, online issue of Neurology®, the medical journal of the American Academy of Neurology.

16 Oct 2024

Groundbreaking discovery offers hope for patients suffering from toxic epidermal necrolysis

A global team of researchers at the Max Planck Institute of Biochemistry has made a groundbreaking discovery that saves the lives of patients suffering from toxic epidermal necrolysis.

16 Oct 2024

Study provides detailed analysis of mRNA vaccine circulation and breakdown

A study led by researchers from RMIT University and the Doherty Institute has provided the first detailed analysis of how mRNA vaccines circulate and break down in the human bloodstream.

16 Oct 2024

Sapio Sciences enhances bioanalysis LIMS and ELN with advanced immunogenicity capabilities

Sapio Sciences, the science-aware™ lab informatics platform, today announced the addition of new immunogenicity bioanalysis features to its industry-leading lab informatics platform.

From Sapio Sciences 16 Oct 2024

AI models boost detection of cognitive decline in medical records, study finds

This study assesses large language models for early detection of cognitive decline, highlighting their strengths and limitations compared to conventional AI.

16 Oct 2024

Antibody engineering drives innovation in drug development

Monoclonal antibodies (mAbs) are used to prevent, detect, and treat a broad spectrum of non-communicable and communicable diseases. Over the past few years, the market for mAbs has grown exponentially with an expected compound annual growth rate (CAGR) of 11.07% from 2024 (237.64 billion USD estimated at the end of 2023) to 2033 (679.03 billion USD expected by the end of 2033).

16 Oct 2024

Harnessing the power of miRNA for cancer diagnosis and treatment

This study is led by Dr. Shiwei Duan (Department of Clinical Medicine, School of Medicine, Hangzhou City University, Hangzhou, Zhejiang, China). His team analyzed literature on miRNA, summarizing the close relationship between these small molecules and cancer. miRNA is a type of non-coding RNA that does not encode proteins, but can target more than 60% of human protein-coding genes.

15 Oct 2024

Bias awareness helps bridge the gap between human and AI healthcare

While people are growing more accustomed to AI-driven personal assistants, customer service chatbots and even financial advisors, when it comes to healthcare, most still want it with a human touch.

15 Oct 2024

Innovative bacteria-based therapy shows promise against cancer

Even as cancer remains a leading cause of death globally, bacteria-based cancer therapy presents an exciting and innovative treatment option.

15 Oct 2024

Efficacy News and Research

New glucose-sensitive insulin NNC2215 could transform diabetes care by lowering hypoglycemia risk

Novel method boosts MSC efficacy for articular cartilage repair

New combination treatment authorized for unresectable urothelial cancer patients

Sapio Sciences enhances lab informatics platform with new immunogenicity bioanalysis features

Researchers uncover the potential of JAK inhibitors to treat life-threatening skin disease

Edaravone shows promise in targeting brain tumor stem cells

New grant aims to transform treatment for liver cancer

Trial evaluates monoclonal antibodies for long COVID prevention

FDA strengthens AI regulation to ensure patient safety and innovation in healthcare

Expanding access to GLP-1 weight-loss drugs could save thousands of lives

Groundbreaking antimicrobial bandage offers rapid hemostasis in accidents

Clot-busting drug tenecteplase shows promising results for stroke recovery

Groundbreaking discovery offers hope for patients suffering from toxic epidermal necrolysis

Study provides detailed analysis of mRNA vaccine circulation and breakdown

Sapio Sciences enhances bioanalysis LIMS and ELN with advanced immunogenicity capabilities

AI models boost detection of cognitive decline in medical records, study finds

Antibody engineering drives innovation in drug development

Harnessing the power of miRNA for cancer diagnosis and treatment

Bias awareness helps bridge the gap between human and AI healthcare

Innovative bacteria-based therapy shows promise against cancer

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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