Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

DNAm measures of biological aging linked with neuropsychologically-validated cognitive decline in midlife

A new research paper was published in Aging (listed as "Aging (Albany NY)" by MEDLINE/PubMed and "Aging-US" by Web of Science) Volume 14, Issue 23, entitled, "DNA methylation-based measures of biological aging and cognitive decline over 16-years: preliminary longitudinal findings in midlife."

30 Dec 2022

AI won't replace radiologists, yet!

A recent study published in The British Medical Journal tested whether artificial intelligence (AI) could pass the examination for the Fellowship of the Royal College of Radiologists (FRCR).

28 Dec 2022

New test detects biomarker of Alzheimer's disease neurodegeneration in blood samples

A group of neuroscientists led by a University of Pittsburgh School of Medicine researcher developed a test to detect a novel marker of Alzheimer's disease neurodegeneration in a blood sample. A study on their results was published today in Brain.

28 Dec 2022

Cell-based method can predict how breast cancer patients will respond to treatments

Researchers at Karolinska Institutet in Sweden have developed a method that should be able to predict whether a patient with breast cancer will benefit from a particular treatment or not.

27 Dec 2022

Breached dolphin's brains show neuropathology similar to Alzheimer's

In a new European Journal of Neuroscience study, scientists studied the brains of Odontocetes (Toothed whales) to document the presence or absence of neuropathological hallmarks of AD.

25 Dec 2022

UTSW researchers identify molecular function of 87 inherited genetic variants linked to prostate cancer

UT Southwestern researchers have identified the molecular function of 87 inherited genetic variants that affect the risk of prostate cancer, and the majority appear to control the activity of genes located far away from the risk variants themselves.

23 Dec 2022

AI method can make time-sensitive, critical diagnosis easier and more accessible to pathologists

When a patient undergoes a surgical operation to remove a tumor or treat a disease, the course of surgery is often not predetermined.

23 Dec 2022

Cellular models based on reprogrammed human cells could boost development of efficient therapies

Studies on diseases that affect the human brain are usually based on animal models which cannot reproduce the complexity of human neuropathies.

22 Dec 2022

Decade-long search in one-celled, fresh water dwelling organism solves puzzle involved in gene regulation

After an intrepid, decade-long search, Johns Hopkins Medicine scientists say they have found a new role for a pair of enzymes that regulate genome function and, when missing or mutated, are linked to diseases such as brain tumors, blood cancers and Kleefstra syndrome - a rare genetic, neurocognitive disorder.

22 Dec 2022

3D neutron tomography reveals water diffusion across the bone material

What keeps bones able to remodel themselves and stay healthy? A team from Charité Berlin has discovered clues to the key function of non-collagen protein compounds and how they help bone cells react to external load.

22 Dec 2022

New methods can advance the development of rapid diagnostics for many infectious diseases

Two companion studies report new artificial intelligence approaches for identification of molecular "fingerprints" for specific infections. The methods, used here to derive a fingerprint for COVID-19, can advance the development of rapid diagnostics for many infectious diseases.

21 Dec 2022

Recapitulating early stages of the human body plan in a dish

Although Michelangelo's masterpiece David captured the magnificence of the human body - how this exquisite body plan is exactly established during human development has puzzled scientists for more than a century.

21 Dec 2022

Study reveals why human lymph nodes lose their function with age

A new study from researchers at Uppsala University presents novel findings on why human lymph nodes lose their function with age and the consequences for the effectiveness of our immune system. The article has been published in The Journal of Pathology.

21 Dec 2022

Research links mutation that causes Huntington's disease to developmental deficits in the brain's oligodendrocyte cells

A research team led by the University of California, Irvine has linked the mutation that causes Huntington's disease to developmental deficits in the brain's oligodendrocyte cells that are caused by changes in metabolism.

21 Dec 2022

Study shows common synthetic food dye as a potential dietary trigger for IBDs

Long-term consumption of Allura Red food dye can be a potential trigger of inflammatory bowel diseases (IBDs), Crohn's disease and ulcerative colitis, says McMaster University's Waliul Khan.

20 Dec 2022

Phenotypic plasticity may allow cancer cells to evade standard therapy

Glioblastomas (GBMs) are incurable brain tumors with a prognosis of about one-and-a half years on average. They are highly resistant to treatment and have defied all attempts at precision therapy.

20 Dec 2022

SARS-CoV-2 structural proteins trigger periodontal fibrosis

Researchers examined the pathological impacts of the structural components of SARS-CoV-2 on human periodontal cells and tissue to understand the association between coronavirus disease 2019 (COVID-19) and deteriorating oral health.

20 Dec 2022

The official who investigates suspicious deaths in your town may be a doctor — or not

When a group of physicians gathered in Washington state for an annual meeting, one made a startling revelation: If you ever want to know when, how — and where — to kill someone, I can tell you, and you’ll get away with it. No problem.

20 Dec 2022

Fujifilm announces asset purchase agreement with Inspirata, Inc. to acquire the company’s digital pathology business

FUJIFILM Corporation (President and CEO, Representative Director: Teiichi Goto) today announced the company has entered into an asset purchase agreement to acquire the global digital pathology business of Tampa, Florida-based Inspirata, Inc. Upon completion of this agreement, Inspirata's Dynamyx® digital pathology technology, employees and customers will become part of Fujifilm.

From FUJIFILM Corporation 20 Dec 2022

Long-lived Chilean rodent is a useful model of natural sporadic Alzheimer's Disease

Led by researchers from the University of California at Irvine, a new study reveals that a long-lived Chilean rodent, called Octodon degus (degu), is a useful and practical model of natural sporadic Alzheimer's Disease.

20 Dec 2022

Pathology News and Research

Further Reading

DNAm measures of biological aging linked with neuropsychologically-validated cognitive decline in midlife

AI won't replace radiologists, yet!

New test detects biomarker of Alzheimer's disease neurodegeneration in blood samples

Cell-based method can predict how breast cancer patients will respond to treatments

Breached dolphin's brains show neuropathology similar to Alzheimer's

UTSW researchers identify molecular function of 87 inherited genetic variants linked to prostate cancer

AI method can make time-sensitive, critical diagnosis easier and more accessible to pathologists

Cellular models based on reprogrammed human cells could boost development of efficient therapies

Decade-long search in one-celled, fresh water dwelling organism solves puzzle involved in gene regulation

3D neutron tomography reveals water diffusion across the bone material

New methods can advance the development of rapid diagnostics for many infectious diseases

Recapitulating early stages of the human body plan in a dish

Study reveals why human lymph nodes lose their function with age

Research links mutation that causes Huntington's disease to developmental deficits in the brain's oligodendrocyte cells

Study shows common synthetic food dye as a potential dietary trigger for IBDs

Phenotypic plasticity may allow cancer cells to evade standard therapy

SARS-CoV-2 structural proteins trigger periodontal fibrosis

The official who investigates suspicious deaths in your town may be a doctor — or not

Fujifilm announces asset purchase agreement with Inspirata, Inc. to acquire the company’s digital pathology business

Long-lived Chilean rodent is a useful model of natural sporadic Alzheimer's Disease

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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