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Mayo Clinic researchers create organoid models for uveal melanoma study

Mayo Clinic researchers have developed organoid models to study uveal melanoma, one of the most common types of eye cancer in adults.

29 Jan 2025

Study identifies potential gain of function mutation in retinoblastoma

A new research paper was published in Volume 16 of Genes & Cancer on January 20, 2025, entitled, "Analysis of pathogenic variants in retinoblastoma reveals a potential gain of function mutation."

29 Jan 2025

New compound Z526 combats cancer-associated cachexia in preclinical models

In a recent study, researchers demonstrated that Z526, a novel dithiocarbamate-like compound, mitigates cancer-associated cachexia (CAC) both in vitro and in vivo.

29 Jan 2025

New treatment identified for peripheral nerve sheath tumors

A multicenter collaboration led by the Bellvitge Biomedical Research Institute (IDIBELL) - Institut Català d'Oncologia (ICO) and the Germans Trias i Pujol Research Institute (IGTP) identified a potential new treatment for an aggressive sarcoma arising in the nerves.

28 Jan 2025

T cells grown with new technique offer better cancer defense

Researchers from the University of Pittsburgh have developed a new way to grow T cells in the lab that enables them to live longer and better destroy cancer cells in a mouse model of melanoma compared to those grown in traditional growth media.

28 Jan 2025

New system uses acoustic waves to separate tumor cells with precision

Cancer accounted for nearly 10 million deaths in 2020 – almost one in every six deaths globally – according to the World Health Organization.

28 Jan 2025

Study uncovers distinct blood protein signature in children with Long COVID

Distinct protein profiles linked to inflammation and angiogenesis found in children with Long COVID, paving the way for improved diagnostics and therapies.

28 Jan 2025

Developmental epigenetic changes could shape cancer risk later in life

A person's lifetime risk for cancer may begin before they are even born, reports a paradigm-shifting study by Van Andel Institute scientists.

27 Jan 2025

Tracking cfDNA levels may help better evaluate surgery colorectal cancer effectiveness

A new research paper was published in Oncotarget's Volume 16 on January 21, 2025, titled "Assessment of cfDNA release dynamics during colorectal cancer surgery."

27 Jan 2025

New therapy shows promise in treating basal cell carcinoma

Basal cell carcinomas, the most common form of skin cancer, occur in chronically sun-exposed areas such as the face.

27 Jan 2025

New nanosystem offers hope for improved diagnosis and treatment of tongue cancer

A pioneering study has unveiled the Au-HN-1 nanosystem, a cutting-edge approach that promises to transform the diagnosis and treatment of tongue squamous cell carcinoma (TSCC).

27 Jan 2025

Early detection of tumor spread improves treatment outcomes

A group led by the Department of Neurosurgery, Brain Research Institute, Niigata University succeeded in the diagnosis of leptomeningeal disease in diffuse midline gliomas by detecting H3K27M-mutant droplets from circulating tumor DNA of cerebrospinal fluid taken from these patients.

27 Jan 2025

Triple therapy shows strong response in BRAF V600E mutant metastatic colorectal cancer

Patients with metastatic colorectal cancer (mCRC) harboring BRAF V600E mutations benefitted from first-line treatment with the targeted therapies encorafenib and cetuximab plus a mFOLFOX6 chemotherapy regimen, according to results from the Phase III BREAKWATER trial led by researchers at The University of Texas MD Anderson Cancer Center.

26 Jan 2025

Blood test for ctDNA identifies patients who benefit from celecoxib after surgery

A data analysis from a randomized clinical trial for stage 3 colon cancer patients by investigators at Dana-Farber Brigham Cancer Center found that patients with evidence of residual cancer in their blood after surgery to remove the cancer, may benefit from adding of celecoxib, to post surgery treatment.

26 Jan 2025

AstraZeneca receives positive NICE recommendations for lung cancer treatment

AstraZeneca announced that this week it has received two positive recommendations from the National Institute for Health and Care Excellence (NICE) for the treatment of lung cancer patients across England and Wales.

25 Jan 2025

Immune environment found to influence success of leukemia immunotherapy

A research team from Columbia Engineering and the Irving Institute for Cancer Dynamics made a pivotal discovery in the field of cancer immunotherapy.

24 Jan 2025

New approach uses peptides to enhance anti-tumor drug formulations

A team of scientists has developed a groundbreaking approach using specially designed peptides to improve drug formulations.

24 Jan 2025

UH Seidman Cancer Center introduces advanced Varian Ethos 2.0 for cancer treatment

Radiation oncologists at UH Seidman Cancer Center have another powerful treatment option for patients diagnosed with many forms of cancer with the addition of Varian Ethos 2.0, capable of a new form of radiotherapy called adaptive radiotherapy.

24 Jan 2025

Researchers identify key factors for successful donor lymphocyte infusion in AML patients

Dana-Farber Cancer Institute researchers have identified factors that determine whether donor lymphocyte infusion (DLI), a standard therapy for patients with acute myeloid leukemia (AML) who have relapsed after allogenic hematopoietic stem cell transplant, will successfully move the patient into remission.

24 Jan 2025

Mapping the human virome to improve disease prevention and treatment

You, my friend, are what scientists call a "holobiont"- an organism made up of human cells and the multiplicity of microscopic species living inside you and on your body.

24 Jan 2025