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MIT researchers develop new nanodevice that can help overcome drug resistance

Chemotherapy often shrinks tumors at first, but as cancer cells become resistant to drug treatment, tumors can grow back. A new nanodevice developed by MIT researchers can help overcome that by first blocking the gene that confers drug resistance, then launching a new chemotherapy attack against the disarmed tumors.

3 Mar 2015

KU Leuven researchers devise simple, effective solution to untangle DNA

Researchers have long sought an efficient way to untangle DNA in order to study its structure - neatly unraveled and straightened out - under a microscope. Now, chemists and engineers at KU Leuven, in Belgium, have devised a strikingly simple and effective solution: they inject genetic material into a droplet of water and use a pipet tip to drag it over a glass plate covered with a sticky polymer.

27 Feb 2015

U of T Scarborough professor develops new compound that can lead to cheaper anti-cancer drugs

A new compound developed at the University of Toronto Scarborough could play an important role in developing cheaper anti-cancer drugs.

26 Feb 2015

New TAU study may offer hope to people diagnosed with Glioblastoma multiforme

There are no effective available treatments for sufferers of Glioblastoma multiforme (GBM), the most aggressive and devastating form of brain tumor. The disease, always fatal, has a survival rate of only 6-18 months.

25 Feb 2015

Neurodegenerative disease research using NMR: an interview with Christian Griesinger

Christian Griesinger, director of the NMR-based Structural Biology department at the Max-Planck Institute for Biophysical Chemistry, talks about his research into neurodegenerative diseases using NMR to examine the dynamics of disordered proteins.

From Bruker BioSpin Group 23 Feb 2015

Targeted nanomedicines could help prevent heart attacks caused by atherosclerosis

Nanometer-sized "drones" that deliver a special type of healing molecule to fat deposits in arteries could become a new way to prevent heart attacks caused by atherosclerosis, according to a study in pre-clinical models by scientists at Brigham and Women's Hospital and Columbia University Medical Center.

19 Feb 2015

UT Dallas study reports new gene therapy approach

Bioengineers at The University of Texas at Dallas have created a novel gene-delivery system that shuttles a gene into a cell, but only for a temporary stay, providing a potential new gene-therapy strategy for treating disease.

19 Feb 2015

Caris Life Sciences announces record-setting revenue for 2014

Caris Life Sciences, a leading biosciences company focused on fulfilling the promise of precision medicine, today announced select year-end financial and operational results for 2014, which include record-setting revenue and continued case volume growth for its panomic, comprehensive tumor profiling service, Caris Molecular Intelligence.

18 Feb 2015

Applying NMR to biological problems: an interview with Professor Arthur Palmer

Our current focus is on areas in protein folding, molecular recognition by proteins and also enzyme catalysis. NMR spin relaxation is one of the very powerful techniques in NMR for studying conformational dynamics in proteins or chemical kinetic processes.

From Bruker BioSpin Group 17 Feb 2015

POCARED Diagnostics announces closure of another $15M in funding

POCARED Diagnostics Ltd. is an Israeli-based Diagnostics and Pre-analytical technology manufacturer with offices in the United States announced they have closed another $15 Million in funding.

17 Feb 2015

Tissue and cell diagnostics market reaches $7.7 billion in 2014

With fast and effective testing techniques, the tissue and cell diagnostics market was estimated to have reached $7.7 billion in 2014 for in vitro diagnostic (IVD) and other reagents used by clinical laboratories, according to Kalorama Information.

16 Feb 2015

AXT adds TriFoil imaging products to their preclinical imaging portfolio

TriFoils flagship is the Triumph tri-modal imaging system that incorporates PET/SPECT and CT technologies all in a single instrument. It has a bore size of 15cm and an axial view of 30cm making ideal for small animal studies.

From MR Solutions 13 Feb 2015

Understanding the pattern of cellular changes that lead to retinal ganglion cell death in glaucoma

Glaucoma, the second leading cause of blindness, usually stems from elevated eye pressure, which in turn damages and destroys specialized neurons in the eye known as retinal ganglion cells. To better understand these cellular changes and how they influence the progression and severity of glaucoma, researchers at University of California, San Diego School of Medicine and Shiley Eye Institute turned to a mouse model of the disease.

12 Feb 2015

AXT establishes preclinical imaging portfolio with MR solutions product lines

To coincide with the start of Lorne Cancer conference, AXT are proud to announce the commencement of their distributorship with MR SOLUTIONS, a world leader in the development of innovative preclinical imaging solutions

From MR Solutions 11 Feb 2015

Virginia Tech purchases two Bruker fluorescence microscope solutions

The Vutara 350 can break the optical diffraction limit by an order of magnitude, opening up a myriad of research opportunities in single-molecule cellular processes.

From Bruker 11 Feb 2015

Researchers generate new reporter system to study bone regeneration potential of embryonic stem cells

A new reporter system used to study the bone regeneration potential of human embryonic stem cells has been generated in research led by the University of Minnesota. The new reporter system is the first of its kind for human pluripotent stem cells and is important for identifying certain agents and pathways that mediate early stages of human bone development.

11 Feb 2015

Andor Zyla sCMOS Camera enables instantaneous imaging of neuronal activity across whole organism for the first time

The speed, resolution and sensitivity of the Andor Zyla sCMOS camera has allowed the Vaziri research group in Vienna, Austria, to simultaneously image neuronal activity across an entire organism for the first time.

10 Feb 2015

New Endoscopic Technique

A flexible wide-field endoscope utilising blue excitation light provides label-free contrast of tissue based on fluorescence lifetime imaging of tissue autofluorescence.

10 Feb 2015

Study describes novel screening system that has potential to uncover effective ovarian cancer drugs

University of Chicago Medicine researchers have built a model system that uses multiple cell types from patients to rapidly test compounds that could block the early steps in ovarian cancer metastasis. Their three-dimensional cell-culture system, adapted for high-throughput screening, has enabled them to identify small molecules that can inhibit adhesion and invasion, preventing ovarian cancers from spreading to nearby tissues.

10 Feb 2015

Accessible TIRF solutions for every application

Olympus expands its range of cellTIRF illuminators and accessories with the new economic one-line illuminator (cellTIRF-1L), which complements the high-end, 4- and 2-line (cellTIRF MITICO 4L/2L) illuminators.

From Evident Corporation - Life Sciences 10 Feb 2015

Fluorescence News and Research

MIT researchers develop new nanodevice that can help overcome drug resistance

KU Leuven researchers devise simple, effective solution to untangle DNA

U of T Scarborough professor develops new compound that can lead to cheaper anti-cancer drugs

New TAU study may offer hope to people diagnosed with Glioblastoma multiforme

Neurodegenerative disease research using NMR: an interview with Christian Griesinger

Targeted nanomedicines could help prevent heart attacks caused by atherosclerosis

UT Dallas study reports new gene therapy approach

Caris Life Sciences announces record-setting revenue for 2014

Applying NMR to biological problems: an interview with Professor Arthur Palmer

POCARED Diagnostics announces closure of another $15M in funding

Tissue and cell diagnostics market reaches $7.7 billion in 2014

AXT adds TriFoil imaging products to their preclinical imaging portfolio

Understanding the pattern of cellular changes that lead to retinal ganglion cell death in glaucoma

AXT establishes preclinical imaging portfolio with MR solutions product lines

Virginia Tech purchases two Bruker fluorescence microscope solutions

Researchers generate new reporter system to study bone regeneration potential of embryonic stem cells

Andor Zyla sCMOS Camera enables instantaneous imaging of neuronal activity across whole organism for the first time

New Endoscopic Technique

Study describes novel screening system that has potential to uncover effective ovarian cancer drugs

Accessible TIRF solutions for every application

Choosing the right benchtop fluorescence microscope: A practical buyer's guide eBook

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Expanding access to NMR with the Fourier 80 Duo