Bioinformatics News and Research

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Bioinformatics is the application of information techniques for the storage, retrieval, and analysis of large quantities of biological data.

New biological age clock estimates how well someone is aging

A team of international researchers has developed a new biological age "clock" that estimates how well someone is aging, not just how "old" they or their various organs might be.

5 Jun 2025

Experts chart path to bring microbiome science into routine clinical care

Despite rapid advances in sequencing and bioinformatics, translating microbiome science into clinical practice presents significant challenges, including the lack of standardized protocols, limited clinical evidence, and logistical barriers. This Cell perspective outlines key actions, standardization, robust trial design, and clinician education to move microbiome diagnostics and therapeutics from bench to bedside.

2 Jun 2025

Gene expression study reveals clues to asbestos-linked mesothelioma

Gene expression leading to alterations in the DNA caused by asbestos exposure may explain the development of Malignant Pleural Mesothelioma (MPM), a rare and aggressive cancer.

31 May 2025

Therapeutic plasma exchange combined with intravenous immunoglobin reduces biological age

A first-of-its-kind clinical trial clinical trial shows that therapeutic plasma exchange (TPE) combined with intravenous immunoglobin reduced biological age on average by 2.6 years, as measured by multi-omic biomarkers.

28 May 2025

Molecular psychiatrist redefines the genetic basis of neurodevelopmental conditions

In a comprehensive Genomic Press interview published today, Professor Barbara Franke unveils her remarkable scientific journey from an inquisitive child fascinated by nature to becoming one of the world's most influential researchers in biological psychiatry.

27 May 2025

AI tools show limitations in diagnosing atypical emergency room cases

Artificial intelligence tools can assist emergency room physicians in accurately predicting disease but only for patients with typical symptoms, West Virginia University scientists have found.

23 May 2025

Machine learning tool identifies metabolic clues in colorectal cancer

Scientists aiming to advance cancer diagnostics have developed a machine learning tool that is able to identify metabolism-related molecular profile differences between patients with colorectal cancer and healthy people.

22 May 2025

Confocal microscopy may help identify biomarkers for chemotherapy-induced neuropathy

A University of Arizona Comprehensive Cancer Center researcher received a $2.4 million National Cancer Institute grant to develop a noninvasive, confocal microscope to examine nerve endings of cancer patients with chemotherapy-induced peripheral neuropathy in the hopes of identifying potential biomarkers for the disease.

22 May 2025

New multiple myeloma-like score assesses disease severity and risk of progression to active cancer

A new risk assessment score developed by researchers at Dana-Farber Cancer Institute and the Broad Institute of MIT and Harvard reveals how multiple myeloma, a form of blood cancer, begins and progresses from precancerous to malignant states by tracing DNA mutations.

21 May 2025

Study reveals subtle effects of recessive mutations on health and reproduction

As a group, carriers of recessive disorders are slightly less healthy and have a reduced chance of having offspring.

16 May 2025

Taurine identified as a key regulator of myeloid cancers

A new scientific study identified taurine, which is made naturally in the body and consumed through some foods, as a key regulator of myeloid cancers such as leukemia, according to a paper published in the journal Nature.

14 May 2025

Researchers uncover how Entamoeba histolytica evades the immune system

The single-celled parasite Entamoeba histolytica infects 50 million people each year, killing nearly 70,000. Usually, this wily, shape-shifting amoeba causes nothing worse than diarrhea.

12 May 2025

Oxford study reveals how COVID-19 vaccines prevent severe illness

A landmark study by scientists at the University of Oxford, has unveiled crucial insights into the way that COVID-19 vaccines mitigate severe illness in those who have been vaccinated.

9 May 2025

MicroRNA breakthrough offers hope for dental bone regeneration

Dental caries, or tooth decay, is a common oral health condition that often causes significant pain and discomfort and may even lead to tooth loss.

8 May 2025

Precision medicine approach improves treatment for soft tissue sarcomas

A study conducted by researchers from the Agency for Science, Technology and Research (A*STAR), National Cancer Centre Singapore (NCCS) and National University of Singapore (NUS), in collaboration with biotech company, KYAN Technologies, has demonstrated that a precision medicine approach improves treatment selection for patients with soft tissue sarcomas (STS) in a clinical setting.

7 May 2025

New biomarkers and therapeutic targets identified for abdominal aortic aneurysm

Announcing a new article publication for Cardiovascular Innovations and Applications journal. This article aimed to identify molecular candidates to serve as diagnostic biomarkers and therapeutic targets for abdominal aortic aneurysm (AAA).

5 May 2025

MD Anderson researchers present promising clinical trial results at AACR 2025

Researchers from The University of Texas MD Anderson Cancer Center will present promising results from clinical trials in three minisymposia abstracts at the American Association for Cancer Research (AACR) Annual Meeting 2025.

26 Apr 2025

Weill Cornell Medicine leads effort to catalog the normal human virome

A major new effort at Weill Cornell Medicine seeks to catalog the normal human virome, the immense ecosystem of viruses that lives in and on us.

25 Apr 2025

AI tools improve detection of key immune structures in melanoma

Researchers from the ECOG-ACRIN Cancer Research Group (ECOG-ACRIN) have applied AI-driven processes for detecting tertiary lymphoid structures (TLS) in thousands of digital images of melanoma tumor tissue, significantly enhancing TLS identification and survival predictions for operable stage III/IV patients.

24 Apr 2025

H5N1's evolutionary leap could undermine vaccines and heighten human infection risk

From egg prices to pet food recalls – and now, confirmation that another strain of bird flu has infected a large commercial flock of broiler chickens on a Mississippi farm – headlines are capturing escalating concern over H5N1's spread.

24 Apr 2025