Biomarker News and Research

RSS

A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

FDA accepts immunotherapy drug for review in colon cancer treatment

The Alliance for Clinical Trials in Oncology (Alliance) today announced that the U.S. Food and Drug Administration has accepted for review Genentech's supplemental Biologic License Application for their immunotherapy drug atezolizumab (Tecentriq®) for the treatment of patients with stage III colon cancer with deficient deoxyribonucleic acid (DNA) mismatch repair (dMMR).

11 Jun 2026

Running a marathon triggers measurable heart changes

Acute cardiac responses to marathon running include biomarker spikes and structural changes, though their long-term impact on heart health needs further study.

11 Jun 2026

Dietary guidelines fail to deliver flavanol levels linked to heart health

A study shows existing dietary recommendations fail to meet flavanol intake levels linked to cardiovascular benefits, indicating a need for targeted guidelines.

11 Jun 2026

Advancing Cushing's syndrome diagnosis with salivary cortisone testing

Discover expert insights into Cushing's syndrome diagnosis using salivary cortisone testing and LC-MS/MS for improved accuracy.

From Waters Advanced Diagnostics 10 Jun 2026

Critical Path Institute opens registration for 2026 Global Impact Conference

Critical Path Institute (C-Path) will host its 2026 Global Impact Conference (CGIC) this September at the Washington Marriott at Metro Center in Washington, D.C.

10 Jun 2026

Review explores impact of extreme endurance running on heart health

Changes to the heart linked to marathon running vary by age, sex, and training level, finds a synthesis of the available data, published in the open access journal BMJ Open Sport & Exercise Medicine.

10 Jun 2026

Active β-catenin promotes aggressive spread of childhood bone cancer

A new research paper was recently published in Volume 17 of Genes & Cancer, titled "Active Beta-Catenin (ABC) promotes an invasive phenotype in pediatric osteosarcoma."

9 Jun 2026

New geroscience initiative aims to accelerate anti‑aging therapies

Albert Einstein College of Medicine has launched the Batia and Idan Ofer program for Validation of Interventions Targeting Aging and Longevity (BIO-VITAL), a new initiative designed to help biotechnology and pharmaceutical companies advance therapies that target the biology of aging.

9 Jun 2026

Trial shows safety of TTV-guided immunosuppression in kidney transplant recipients

An international research team coordinated by the Medical University of Vienna has demonstrated in a clinical trial that Torque-Teno-virus-guided dosing of immunosuppressants in kidney transplant recipients is safe.

8 Jun 2026

Specific fruit choices boost flavanols for a healthier heart

Including blueberries, plums, blackberries, broad beans or cherries (washed down with green tea) in your five-a-day may be the best way to a healthier heart, new research suggests.

8 Jun 2026

Flu drugs may reduce cognitive decline in people with HIV

A class of flu drugs may reduce cognitive decline and premature aging in people living with chronic viral infection, reports a new study led by Northwestern University that began with blood samples from people with HIV and extended into preclinical drug trials.

5 Jun 2026

Study reveals distinct sociodemographic risk factors in rare myopathies

Idiopathic inflammatory myopathies (IIM) are a heterogenous group of autoimmune conditions with substantial morbidity.

5 Jun 2026

Vaping devices and flavors affect genes differently

Vaping exposure affects gene activity in the mouth, with variations linked to device type and flavor, suggesting unique molecular responses compared to smoking.

4 Jun 2026

ELRIG unveils keynote speakers for Drug Discovery 2026

ELRIG, a not-for-profit, volunteer-led organization dedicated to the global drug discovery community, today announced the keynote speaker program for Drug Discovery 2026.

From ELRIG (UK) Ltd. 3 Jun 2026

Novel theranostic approach targets aggressive neuroendocrine prostate cancer

A novel theranostic approach that targets RET -- a newly identified biomarker for neuroendocrine prostate cancer enables high-contrast PET imaging and effective, safe treatment for this highly aggressive malignancy.

2 Jun 2026

Introducing Evosep Proteomics to standardize and scale proteomics for research and drug development

Evosep announces the launch of Evosep Proteomics, an ecosystem designed to standardize and scale LC-MS-based proteomics for research and pharmaceutical drug development.

From Evosep 2 Jun 2026

New atlas provides unprecedented overview of dendritic cell diversity across cancers

Researchers from VIB, VUB, and an international network of collaborators have created the most comprehensive single-cell atlas to date of tumor-associated dendritic cells.

1 Jun 2026

Lower Alzheimer’s amyloid levels in Black and Latinx adults

Findings show lower amyloid PET positivity in Black and Latinx adults with cognitive impairment, highlighting disparities in dementia diagnosis and treatment.

1 Jun 2026

New PET imaging tracks tumor progression and cardiac inflammation during cancer therapy

A novel PET imaging approach enables simultaneous visualization of tumor progression and cardiac inflammatory responses during cancer treatment.

1 Jun 2026

Hypoxia-gated AAV enables targeted treatment for advanced NSCLC

Adeno‑associated virus (AAV) vectors offer safety and durable expression but lack tumor specificity. This hypothesis proposes an NSCLC‑directed, hypoxia‑responsive AAV platform that integrates MGS4 peptide‑guided capsid targeting with dual hypoxia‑responsive element (HRE)‑gated promoters driving Q‑CXCL9‑Fc (chemokine) and miR‑30‑based shRNA against mesothelin (MSLN).

1 Jun 2026