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Study uncovers new molecular mechanisms linked to Alzheimer's cognitive decline

A research team at the University of Barcelona's Institute of Neurosciences (UBneuro) has discovered new molecular mechanisms related to the cognitive decline associated with Alzheimer's disease, the most common dementia.

26 May 2025

Study uncovers new factor linked to the development of cardiac hypertrophy

When the workload on the heart increases, the ventricular wall may thicken too, known as cardiac hypertrophy.

22 May 2025

Blocking IL1RAP protein may offer new approach to treat atherosclerosis

Atherosclerosis is the buildup of fat and calcium in the walls of blood vessels and represents the most common cause of cardiovascular disease.

21 May 2025

Breakthrough microimager offers new possibilities for internal imaging

Researchers have developed an extremely thin, flexible imager that could be useful for noninvasively acquiring images from inside the body. The new technology could one day enable early and precise disease detection, providing critical insights to guide timely and effective treatment.

19 May 2025

Research identifies seven genes that drive hematopoietic stem cell fate

Stem cells can produce any other cell type, it is just a matter of telling them in the right way. From a biological perspective, this means activating the proper genetic programme by pressing the right keys, this is, the right genes, at the right moment.

16 May 2025

New candidate compounds show promise for Alzheimer's and pain treatment

A study published in the Journal of Medicinal Chemistry presents a new family of candidate compounds for the treatment of Alzheimer's disease and pain, which have shown promising effects in animal models.

14 May 2025

CAR-T cell therapy linked to brain fog in cancer patients

After treatment with CAR-T cells - immune cells engineered to attack cancer - patients sometimes tell their doctors they feel like they have "brain fog," or forgetfulness and difficulty concentrating.

12 May 2025

How microRNA is transforming science: From discovery to diagnostics

In this interview, industry expert Dr. Lohit Khera discusses the evolving role of microRNA in research, diagnostics, and precision medicine, highlighting the latest innovations in RNA extraction and analysis

From Norgen Biotek Corp. 6 May 2025

Rare TYROBP gene variant found in Finns linked to increased Alzheimer's risk

Found in the Finnish population, a rare variant of the TYROBP gene significantly increases the risk of Alzheimer's disease, a new study led by the University of Eastern Finland shows.

30 Apr 2025

Genetic variation found to influence tumor microbiota and colorectal cancer progression

Colorectal cancer (CRC) is one of the most prevalent cancers worldwide. While scientists believe that gut microbiota play an important role in both the onset and progression of CRC, emerging evidence points to the significance of intratumoral microbiota-microbiota inside tumors-in CRC progression.

29 Apr 2025

Arc Institute expands virtual cell atlas with industry partnerships

Arc Institute continues its work to generate and share large-scale, high-quality datasets of cell state before and after chemical or genetic perturbations to enable "virtual cell" models and other innovations.

28 Apr 2025

Weill Cornell Medicine leads effort to catalog the normal human virome

A major new effort at Weill Cornell Medicine seeks to catalog the normal human virome, the immense ecosystem of viruses that lives in and on us.

25 Apr 2025

Manipulating a master regulator prevents tumor growth in mice

A protein identified nearly 40 years ago for its ability to stimulate the production of red blood cells plays a surprising, critical role in dampening the immune system's response to cancer.

24 Apr 2025

Traditional BMI cut-offs overestimate overweight and obesity in male athletes

New research to be presented at this year's European Congress on Obesity (ECO 2025, Malaga, Spain, 11-14 May) shows that the internationally recognized body mass index (BMI) cut-off points greatly overestimate overweight and obesity in male athletes.

18 Apr 2025

Research explores how photo-oxidized sterols kill melanoma cells

Melanoma is the most aggressive form of skin cancer. Although less common, it is the most serious due to its high potential for metastasis.

16 Apr 2025

Dynamic BH3 profiling offers personalized lung cancer therapies

Eighty-five percent of diagnosed cases of lung cancer are non-small cell lung cancer (NSCLC). In this group, 5% of patients show molecular alterations in the ALK gene involved in cell multiplication.

9 Apr 2025

Novel computational tool helps scientists detect hidden cell types behind disease

Cells throughout the body work together like singers in a choir to keep us healthy, as long as they work in perfect harmony.

7 Apr 2025

New drug shows neuroprotective and anti-inflammatory effects in murine models of Alzheimer's

Alzheimer's disease, the most common cause of dementia, is currently incurable. The current drugs available have very limited efficacy and only in mild stages of the disease.

2 Apr 2025

Stanford study reveals glucose's surprising role in cell differentiation

The sugar glucose, which is the main source of energy in almost every living cell, has been revealed in a Stanford Medicine study to also be a master regulator of tissue differentiation - the process by which stem cells give rise to specialized cells that make up all the body's tissues.

25 Mar 2025