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Dynamic BH3 profiling offers personalized lung cancer therapies

Eighty-five percent of diagnosed cases of lung cancer are non-small cell lung cancer (NSCLC). In this group, 5% of patients show molecular alterations in the ALK gene involved in cell multiplication.

9 Apr 2025

Novel computational tool helps scientists detect hidden cell types behind disease

Cells throughout the body work together like singers in a choir to keep us healthy, as long as they work in perfect harmony.

7 Apr 2025

New drug shows neuroprotective and anti-inflammatory effects in murine models of Alzheimer's

Alzheimer's disease, the most common cause of dementia, is currently incurable. The current drugs available have very limited efficacy and only in mild stages of the disease.

2 Apr 2025

Stanford study reveals glucose's surprising role in cell differentiation

The sugar glucose, which is the main source of energy in almost every living cell, has been revealed in a Stanford Medicine study to also be a master regulator of tissue differentiation - the process by which stem cells give rise to specialized cells that make up all the body's tissues.

25 Mar 2025

Study shows artificial intelligence can improve intravenous nutrition for premature babies

Artificial intelligence can improve intravenous nutrition for premature babies, a Stanford Medicine study has shown.

25 Mar 2025

BMI may no longer be enough for assessing obesity in older adults

Body mass index (BMI) is key method for measuring a person's weight status, and defining if they have normal weight, overweight, or obesity.

19 Mar 2025

Understanding how JAK inhibitors may increase blood clot risk

Why do medications that are supposed to help patients with chronic inflammatory diseases sometimes lead to blood clots?

17 Mar 2025

Bioenergetic age could predict Alzheimer's disease risk

A person's "bioenergetic age"-or how youthfully their cells generate energy-might be a key indicator of whether they're at risk of developing Alzheimer's disease, new research from Weill Cornell Medicine shows.

14 Mar 2025

Innovative gel prevents post-surgery adhesions in animal models

Surgical adhesions - common, sometimes life-threatening complications that arise after open or laparoscopic abdominal surgery - can be prevented in mice and pigs by a gel impregnated with a molecule that blocks a key signaling pathway in the formation of scar tissue.

12 Mar 2025

Limiting screen time and promoting physical activity may help safeguard children’s mental health

A recent Finnish study suggests that limiting screen time and promoting physical activity from childhood may help safeguard mental health in adolescence.

10 Mar 2025

Naturally occurring molecule suppresses appetite and promotes weight loss

A naturally occurring molecule identified by Stanford Medicine researchers appears similar to semaglutide - also known as Ozempic - in suppressing appetite and reducing body weight.

6 Mar 2025

Macrophage-targeted therapy could enhance cardiac regeneration and myocardial repair

A new review published in Genes & Diseases highlights macrophage-targeted therapy as a promising frontier in cardiac regeneration and myocardial repair.

5 Mar 2025

Study elucidates mechanism connecting ER membrane remodeling to pyroptosis in cancer cells

Pyroptosis, a highly inflammatory type of programmed cell death, has garnered attention for its potential in cancer treatment.

3 Mar 2025

Novel mechanism of PDHX acetylation linked to hepatocellular carcinoma progression

Cancer cells are known to favor aerobic glycolysis for energy production, a phenomenon termed the Warburg effect.

3 Mar 2025

Study identifies key role of JMJD1C in acute myeloid leukemia

Acute myeloid leukemia (AML) is one of the most aggressive and genetically complex cancers, marked by the unchecked growth of immature myeloid cells.

3 Mar 2025

Stress granules as potential biomarkers for neurodegenerative diseases

Stress granules (SGs) are transient organelles that form when cells experience stress, serving as critical hubs for RNA metabolism and cellular survival.

3 Mar 2025

Skin organoids show promise for treating frostbite injuries

Frostbite is a severe cold injury that affects millions worldwide, often resulting in prolonged recovery, scarring, and long-term complications such as chronic pain and dysfunction.

3 Mar 2025

AI detects colorectal cancer with high accuracy

A new AI-based tool for identifying colorectal cancer from tissue sample analysis has been developed at the University of Jyväskylä. The new artificial neural network model has surpassed all its predecessors in classification performance. The tool has also been made freely available.

28 Feb 2025

Understanding sex differences in the genetic basis of schizophrenia

A joint research study conducted by the UAB and the UB has analyzed the relation between the genetic risk of having schizophrenia and mild subclinical traits in people of the general population.

26 Feb 2025

Early pregnancy nutrition impacts child's motor development at age 5-6

A healthy diet in early pregnancy supports the child's motor development at the age of 5-6 years. Higher maternal body fat mass, on the other hand, has an adverse effect on the child's motor development.

25 Feb 2025