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Using AI to break the opioid addiction cycle

When Ben Brown, research assistant professor of chemistry, thinks about the opioid epidemic, he views the problem on a molecular level.

19 Jan 2024

Ludwig scientists deconstruct the blood supply of brain metastases

A Ludwig Cancer Research study has generated a granular portrait of how the cellular and molecular components of the blood vessels that feed brain metastases of melanoma and lung and breast cancers differ from those of healthy brain tissue, illuminating how they help shape the internal environment of tumors to support cancer growth and immune evasion.

19 Jan 2024

AI scores breakthrough in anemia treatment with novel PHD inhibitor

Clinical stage generative artificial intelligence (AI)-driven biotechnology company InSilico Medicine ("InSilico"), today announced that the Journal of Medicinal Chemistry, an ACS Publications journal focusing on critical studies about molecular structure and biological activity, has published the company's discovery of a novel PHD inhibitor for the treatment of anemia.

19 Jan 2024

Insilico Medicine leverages AI to identify promising new target for breast and gynecological cancers

Insilico Medicine("Insilico"), a clinical stage generative artificial intelligence (AI)-driven drug discovery company, recently published an early research that it has identified MYT1 as a promising new therapeutic target for breast and gynecological cancer, and discovered a series of novel, potent, and highly selective inhibitors specifically targeting MYT1.

19 Jan 2024

Groundbreaking study identifies FAM3C as a key regulator of breast cancer progression

A groundbreaking study conducted by Professor Jiyoung Park and her research team in the Department of Biological Sciences at UNIST has identified FAM3C, a metabolism-regulating signaling molecule produced by cancer-associated adipocytes (CAAs), as a key regulator of breast cancer progression within the tumor microenvironment (TME).

19 Jan 2024

Study shows Omicron variants evade immune system like predecessors, suggesting key evolutionary trait in SARS-CoV-2

Researchers compared SARS-CoV-2 Omicron variant of concern replication in human cell lines and primary airway cultures and measured host responses to infection.

19 Jan 2024

Researchers develop a potential one-minute COVID-19 test inspired by bioluminescence

Cold, flu and COVID-19 season brings that now-familiar ritual: swab, wait, look at the result. But what if, instead of taking 15 minutes or more, a test could quickly determine whether you have COVID-19 with a glowing chemical?

18 Jan 2024

Important discovery could lead to novel treatment for obesity

A team comprised primarily of Texas A&M AgriLife Research scientists has made an important discovery that could lead to a novel treatment for obesity and obesity-associated diseases or conditions.

18 Jan 2024

New structural insights pave the way for drug-resistant malaria therapies

Structural insights into a potent antimalarial drug candidate's interaction with the malaria parasite Plasmodium falciparum have paved the way for drug-resistant malaria therapies, according to a new study by researchers at Weill Cornell Medicine and Van Andel Institute.

18 Jan 2024

St. Jude announces $13 million investment to expand the understanding of G-protein coupled receptors

St. Jude Children's Research Hospital today announced a nearly $13 million investment toward a new research collaboration with scientists at Columbia University, Duke University and Stanford University to expand the understanding of G-protein coupled receptors (GPCR), which are vital proteins that impact human health and disease.

18 Jan 2024

Decoding blood cancer secrets to optimize CAR T therapy

Chimeric antigen receptor T-cell therapy, or CAR T, has dramatically improved the treatment of certain blood cancers. Initially approved for patients who had failed multiple lines of therapy, clinical trials have shown CAR T can be used as an earlier treatment option.

17 Jan 2024

Spider venom molecule meets benchmarks to treat heart attack and stroke

A spider venom molecule being investigated by a University of Queensland team has met critical benchmarks towards becoming a treatment for heart attack and stroke.

16 Jan 2024

Drinkable, carbon monoxide-infused foam supercharges cancer therapy

Did smokers do better than non-smokers in a clinical trial for an experimental cancer treatment? That was the intriguing question that led University of Iowa researchers and their colleagues to develop a drinkable, carbon monoxide-infused foam that boosted the effectiveness of the therapy, known as autophagy inhibition, in mice and human cells.

12 Jan 2024

Unlocking protein secrets: X-ray crystallography reveals hidden shapes

Proteins do the heavy lifting of performing biochemical functions in our bodies by binding to metabolites or other proteins to complete tasks.

12 Jan 2024

New molecule targets key protein in autoimmune diseases

Scientists from Scripps Research have developed a small molecule that blocks the activity of a protein linked to autoimmune diseases, including systemic lupus erythematosus (SLE) and Crohn's disease.

11 Jan 2024

Study sheds light on how impaired autophagy can play a role in causing heart failure

A new study sheds light on how autophagy, the body's process for removing damaged cell parts, when impaired, can play a role in causing heart failure.

11 Jan 2024

Extended liver preservation technique shows promise for daytime transplants

Phase II clinical trial evaluates the safety and feasibility of prolonged DHOPE for extending human donor liver preservation to 20 hours, showing potential for facilitating daytime liver transplantation.

11 Jan 2024

Study uncovers new weapon against PARP inhibitor-resistant ovarian cancers

A new editorial paper was published in Oncotarget's Volume 14 on December 22, 2023, entitled, "One more step toward treatment of PARP inhibitor-resistant ovarian cancers."

10 Jan 2024

mRNA therapy shows promise for curing children's rare liver disease

By exploiting the technology used in Covid-19 vaccines, a team led by UCL, King's College London and Moderna scientists has created an effective therapy for a rare disease, in a study in mice, demonstrating the technology's potential therapeutic use in people.

10 Jan 2024

Protein secrets revealed: Single-molecule spectroscopy ushers in era of personalized medicine

Infrared vibrational spectrum of a single protein is observed using advanced measurement techniques based on near-field optical microscopy.

9 Jan 2024

Molecule News and Research

Using AI to break the opioid addiction cycle

Ludwig scientists deconstruct the blood supply of brain metastases

AI scores breakthrough in anemia treatment with novel PHD inhibitor

Insilico Medicine leverages AI to identify promising new target for breast and gynecological cancers

Groundbreaking study identifies FAM3C as a key regulator of breast cancer progression

Study shows Omicron variants evade immune system like predecessors, suggesting key evolutionary trait in SARS-CoV-2

Researchers develop a potential one-minute COVID-19 test inspired by bioluminescence

Important discovery could lead to novel treatment for obesity

New structural insights pave the way for drug-resistant malaria therapies

St. Jude announces $13 million investment to expand the understanding of G-protein coupled receptors

Decoding blood cancer secrets to optimize CAR T therapy

Spider venom molecule meets benchmarks to treat heart attack and stroke

Drinkable, carbon monoxide-infused foam supercharges cancer therapy

Unlocking protein secrets: X-ray crystallography reveals hidden shapes

New molecule targets key protein in autoimmune diseases

Study sheds light on how impaired autophagy can play a role in causing heart failure

Extended liver preservation technique shows promise for daytime transplants

Study uncovers new weapon against PARP inhibitor-resistant ovarian cancers

mRNA therapy shows promise for curing children's rare liver disease

Protein secrets revealed: Single-molecule spectroscopy ushers in era of personalized medicine

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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