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Statins show no additional benefit for depression treatment

Lipid-lowering medicines, known as statins, are prescribed in cases of high cholesterol levels, to reduce the risk of atherosclerosis, heart attack and stroke.

4 Jun 2025

AI-designed drug shows early promise for lung fibrosis patients in clinical trial

Researchers report that rentosertib, an AI-discovered TNIK inhibitor, showed promising safety and potential to improve lung function in patients with idiopathic pulmonary fibrosis in a 12-week phase 2a clinical trial. The highest dose group demonstrated a trend toward increased forced vital capacity, especially among patients not receiving standard antifibrotic therapy, supporting further clinical investigation.

4 Jun 2025

New non-invasive method boosts the brain's natural waste drainage system

Scientists at the Institute for Basic Science (IBS) have uncovered a non-invasive method to boost the brain's natural waste drainage system-a discovery that could open new avenues for tackling age-related neurological disorders.

4 Jun 2025

AI and human scientists collaborate to discover new cancer drug combinations

An 'AI scientist', working in collaboration with human scientists, has found that combinations of cheap and safe drugs – used to treat conditions such as high cholesterol and alcohol dependence – could also be effective at treating cancer, a promising new approach to drug discovery.

4 Jun 2025

Researchers map DNA regions that activate liver regeneration

The mammalian liver has an extraordinary regenerative capacity, capable of fully restoring its mass and function after injury or partial resection.

4 Jun 2025

An Arm and a Leg: A mathematical solution for US hospitals?

What do the KGB and the former CEO of Cincinnati Children’s Hospital have in common?

4 Jun 2025

Two patients faced chemo. The one who survived demanded a test to see if it was safe.

JoEllen Zembruski-Ruple, while in the care of New York City's renowned Memorial Sloan Kettering Cancer Center, swallowed the first three chemotherapy pills to treat her squamous cell carcinoma on Jan. 29, her family members said. They didn't realize the drug could kill her.

4 Jun 2025

SWOG S2302 Pragmatica-Lung study demonstrates value of streamlined clinical trials in real world settings

The SWOG S2302 Pragmatica-Lung trial, which broke new ground with its streamlined pragmatic design, unusually broad eligibility criteria, and reduced data collection, has quickly answered its primary question, finding that the investigational combination it tested did not significantly extend overall survival compared to standard of care treatments.

4 Jun 2025

New mouse model sheds light on smell loss and neural regeneration

A new study suggests that stem cells thought to be dormant may offer clues to why our sense of smell declines or is lost.

3 Jun 2025

Understanding antibiotic resistance mechanisms in Mycobacterium species

Announcing a new article publication for BIO Integration journal. Tuberculosis (TB) is caused by Mycobacterium tuberculosis (M.tb) complex (MTBC), which includes M.tb as one of the causative bacteria.

3 Jun 2025

PfSPZ-LARC2 malaria vaccine advances to new age groups after successful safety review

Physician-scientists at Groupe de Recherche Action en Santé (GRAS) in Burkina Faso have successfully completed initial safety evaluations in 30 adult Burkinabés as the first phase of a clinical trial of Sanaria PfSPZ-LARC2 Vaccine, which is designed to prevent infection with Plasmodium falciparum malaria.

3 Jun 2025

Bone medications and steroids linked to increased risk of jaw disease

Certain medications used in the treatment of bone conditions, particularly when combined with corticosteroids, may significantly increase the risk of a rare but serious jaw disease.

3 Jun 2025

Myeloid cells shape tumor microenvironments and influence cancer progression

Recent advances in cancer research have underscored the critical role of myeloid cells in shaping tumor microenvironments (TME), influencing tumor progression, immune evasion, and therapeutic resistance.

3 Jun 2025

Study uncovers how HSV-1 disables the brain's antiviral defense

Infections caused by herpes simplex virus type 1 (HSV-1) can lead to HSV-1 encephalitis-a rare but deadly condition that inflames the brain.

3 Jun 2025

New study stands to improve the rigor and reliability of psychedelic clinical trials

As psychedelics gain traction as potential treatments for mental health disorders, an international study led by researchers at McGill University, Imperial College London, and the University of Exeter stands to improve the rigor and reliability of clinical research.

3 Jun 2025

How soy and gut microbes alter cancer treatment results

Researchers have discovered that plant-derived phytochemicals and their gut microbiome metabolites control the effectiveness of PI3K inhibitors in cancer therapy. The study reveals that dietary components, especially soy compounds processed by gut bacteria, can alter drug metabolism and impact treatment outcomes.

2 Jun 2025

THP regimen achieves high response rates in HER2 positive breast cancer patients

Patients with Stage II and III (early-stage) HER2+ breast cancer usually undergo pre-operative therapy with multi-agent chemotherapy in combination with anti-HER2 antibodies, followed by surgery.

2 Jun 2025

First-in-class antibody-drug conjugate shows high response rates in rare blood cancer trial

The first-in-class antibody-drug conjugate (ADC) pivekimab sunirine (PVEK) demonstrated promising efficacy and high response rates for patients with blastic plasmacytoid dendric cell neoplasm (BPDCN), according to data from a Phase I/II study led by researchers from The University of Texas MD Anderson Cancer Center.

2 Jun 2025

Immunotherapy before surgery boosts long term survival in lung cancer, trial shows

Results from a phase 3 clinical trial published in the New England Journal of Medicine, today (June 2nd) show that patients with lung cancer who received an immunotherapy drug, nivolumab, along with standard chemotherapy before surgery had improved long term survival compared to those who received chemotherapy alone, at 5 years after completing treatment.

2 Jun 2025

Researchers identify gene driving aggressive prostate cancer

Researchers at the University of Michigan Rogel Cancer Center identified a gene that plays a key role in prostate cancer cells that have transitioned to a more aggressive, treatment-resistant form.

2 Jun 2025

Drugs News and Research

Statins show no additional benefit for depression treatment

AI-designed drug shows early promise for lung fibrosis patients in clinical trial

New non-invasive method boosts the brain's natural waste drainage system

AI and human scientists collaborate to discover new cancer drug combinations

Researchers map DNA regions that activate liver regeneration

An Arm and a Leg: A mathematical solution for US hospitals?

Two patients faced chemo. The one who survived demanded a test to see if it was safe.

SWOG S2302 Pragmatica-Lung study demonstrates value of streamlined clinical trials in real world settings

New mouse model sheds light on smell loss and neural regeneration

Understanding antibiotic resistance mechanisms in Mycobacterium species

PfSPZ-LARC2 malaria vaccine advances to new age groups after successful safety review

Bone medications and steroids linked to increased risk of jaw disease

Myeloid cells shape tumor microenvironments and influence cancer progression

Study uncovers how HSV-1 disables the brain's antiviral defense

New study stands to improve the rigor and reliability of psychedelic clinical trials

How soy and gut microbes alter cancer treatment results

THP regimen achieves high response rates in HER2 positive breast cancer patients

First-in-class antibody-drug conjugate shows high response rates in rare blood cancer trial

Immunotherapy before surgery boosts long term survival in lung cancer, trial shows

Researchers identify gene driving aggressive prostate cancer

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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