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Hidden junk DNA could play decisive role in cancer

Many repetitive regions of the genome have been considered "junk DNA" because the technologies available did not allow them to be studied at sufficient resolution.

5 Jun 2026

Novel technology maps single-cell DNA-protein interactions

A new technology allows scientists to map, in single cells, the DNA binding sites of transcription factors and other regulatory proteins that control gene activity, according to a study led by investigators at Weill Cornell Medicine and the New York Genome Center.

4 Jun 2026

Study reveals how breast cancer cells hide in the bone marrow

Treating breast cancer remains a major medical challenge worldwide. This is largely due to the ability of breast cancer cells to remain hidden for years before triggering a relapse, which can occur even decades after successful treatment of the primary tumor.

4 Jun 2026

Researchers discover a biological barrier that limits mucosal vaccine immunity

A consistent biological barrier that stops the immune system from making the antibodies most needed to protect the nose and throat from respiratory viruses has been identified.

4 Jun 2026

Researchers unravel the mechanism behind precise timing of master biological clock

Imagine a train parked at the station. Passengers climb aboard and find their seats. Conductors move up and down the aisles, checking tickets.

3 Jun 2026

Genetically-modified hookworms successfully deliver medicine to animal hosts

Hookworms, intestinal parasites that infect hundreds of millions of people in under-resourced tropical regions around the globe, have evolved to survive inside the human gut for years, secreting molecules that enable co-existence with their hosts.

3 Jun 2026

ELRIG unveils keynote speakers for Drug Discovery 2026

ELRIG, a not-for-profit, volunteer-led organization dedicated to the global drug discovery community, today announced the keynote speaker program for Drug Discovery 2026.

From ELRIG (UK) Ltd. 3 Jun 2026

Allen Institute launches global research initiative to accelerate new treatments for brain disorders

The Allen Institute, together with partner organizations, today launched the Brain Health accelerator: an ambitious global research initiative seeking to identify the specific brain cells and circuits affected in neurodegenerative disease and other brain disorders and use that knowledge to accelerate the development of new treatments.

2 Jun 2026

E-cigarette flavors and device type drive the biological effects of vaping

People who vape regularly show altered activity in 3,124 genes across the genome compared with people who do not smoke or vape.

1 Jun 2026

Pediatric experts reveal the 10 research areas set to shape child health

Pediatric research leaders identified 10 high-promise areas likely to shape child health over the next 5 to 10 years, including genomics, mental health, vaccines, artificial intelligence, perinatal medicine, precision therapeutics, health equity, nutrition, environmental health, and cancer treatment. The paper argues that these opportunities will only translate into better outcomes if pediatric research receives sustained funding, public trust, workforce support, advocacy, and equitable implementation.

1 Jun 2026

Jumping genes help strengthen the mammalian Y chromosome

The humble Y chromosome may be the smallest chromosome in the mammalian genome (and getting even smaller), but it is mighty: genes on the Y chromosome are critical for fertility in males.

1 Jun 2026

Brazilian study links TP53 mutations to poor lung cancer prognosis

Lung cancer is the most common and deadly form of cancer worldwide. It is increasingly understood to be a complex genetic disease with different mutations that vary according to factors such as smoking and ethnicity.

1 Jun 2026

New SMArT platform improves safety of CRISPR gene editing

A team of researchers led by Luigi Naldini at the San Raffaele Telethon Institute for Gene Therapy (SR-Tiget) has developed a new strategy to significantly improve the precision and safety of CRISPR-Cas9 gene editing in human blood stem cells, potentially overcoming one of the major barriers limiting broader clinical application of genome editing therapies.

1 Jun 2026

Hypoxia-gated AAV enables targeted treatment for advanced NSCLC

Adeno‑associated virus (AAV) vectors offer safety and durable expression but lack tumor specificity. This hypothesis proposes an NSCLC‑directed, hypoxia‑responsive AAV platform that integrates MGS4 peptide‑guided capsid targeting with dual hypoxia‑responsive element (HRE)‑gated promoters driving Q‑CXCL9‑Fc (chemokine) and miR‑30‑based shRNA against mesothelin (MSLN).

1 Jun 2026

Grant funds research into molecular memories behind exaggerated fear

Experiencing a traumatic event sometimes produces long-lasting biological changes that can lead to an exaggerated fear response to future stressful events, such as what occurs in individuals with post-traumatic stress disorder (PTSD).

29 May 2026

Brain transposons may influence aging and neurodegenerative disease progression

Transposable elements (TEs), also called transposons, are DNA sequences capable of moving or replicating from one location to another within a genome.

28 May 2026

Scientists develop safer CRISPR technique using gentler DNA nicking approach

Researchers at Cornell University have developed a safer and more precise way to study how genes function in living tissues by refining a recently developed CRISPR-based genetic technique in fruit flies, enabling researchers to better study how genes contribute to development and disease.

27 May 2026

Lung cancer cells change identity to resist medical treatments

Cancer scientists have discovered that lung cancer cells can change their identity to resist treatment.

27 May 2026

Cells detect and silence invading transposons through abnormal RNA signals

Transposons, DNA sequences that can self-replicate and move (jump) throughout the genome, are widespread and can affect cell survival if left unchecked. Cells control these "jumping genes" by silencing them, but little was known about how cells recognize and defend themselves from invading transposons.

26 May 2026

Blood proteins can predict multiple sclerosis years before diagnosis

A new study has revealed a group of blood proteins, that are altered in people who go on to develop multiple sclerosis (MS), in some cases more than a decade before diagnosis.

26 May 2026