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Study finds better breast cancer screening outcomes with tomosynthesis than mammography

In a study of over a million women, digital breast tomosynthesis (DBT) showed improved breast cancer screening outcomes over screening with standard digital mammography alone.

14 Mar 2023

Correcting abnormalities in solid tumor's blood vessels can improve efficacy of CAR-T cell therapy

A type of immune therapy called chimeric antigen receptor (CAR)-T cell therapy has revolutionized the treatment of multiple types of blood cancers but has shown limited efficacy against glioblastoma-;the deadliest type of primary brain cancer-;and other solid tumors.

14 Mar 2023

Distinct microbial profile present in intrahepatic cholestasis of pregnancy patients

Researchers assessed the impact of the gut microbiome on the host's bile acid metabolism and intrahepatic cholestasis of pregnancy (ICP).

14 Mar 2023

SARS-CoV-2 replication persists for weeks in lungs after symptom onset in severe COVID-19

Researchers observe persistent SARS-CoV-2 replication in severe COVID-19 patient lungs.

13 Mar 2023

Abnormally low autoantibody activity significantly associated with autism severity

A recent study hypothesized a dysfunction of the self-recognition properties of the immune system in autism.

13 Mar 2023

What is the effect of low Anti-Müllerian hormone on semen quality?

A recent BMC Medicine study investigated the relationship between Vitamin D and serum Anti-Müllerian hormone (AMH) in infertile men. This study was based on secondary analysis of a randomized clinical trial, which assessed the effect of high-dose Vitamin D plus calcium and placebo on semen quality in Vitamin D deficient infertile men.

10 Mar 2023

Cancer stage and receptor status influence the risk of breast cancer recurrence

New research indicates that for patients with breast cancer, the cancer’s stage and receptor status can help clinicians predict whether and when cancer might recur after initial treatment.

9 Mar 2023

Nasal administration of a fully human anti-CD3 monoclonal antibody modulates T cell inflammatory responses in COVID-19

Researchers assessed the impact of an anti-CD3 monoclonal antibody called Foralumab in COVID-19 treatment.

9 Mar 2023

A shot of liver-produced hormone sobers up drunk mice

A hormone called fibroblast growth factor 21 (FGF21) protects mice against ethanol-induced loss of balance and righting reflex, according to a study publishing on March 7 in the journal Cell Metabolism.

7 Mar 2023

Multi-organ scRNA-seq reveals targeting pro- or anti-inflammatory regulators may be exploited for personalized treatment of immune diseases

Researchers performed multi-organ single-cell RNA sequencing of collagen-induced arthritis murine model to evaluate immune-mediated inflammatory disease alterations by characterizing the genome, organizing the organome, and prioritizing pathways in the multi-organ data.

3 Mar 2023

Research investigates roles of neurotrophic factors on cognition in Alzheimer's patients carrying APOE ε4

Researchers investigate the role of neurotrophic factors on the cognitive performance of Alzheimer’s disease patients carrying the apolipoprotein E 4 gene.

1 Mar 2023

Study reveals synergistic impact of estrogen and intestinal dysbiosis on pulmonary fibrosis

In a recent study published in Cells, researchers evaluated idiopathic pulmonary fibrosis (IPF) pathophysiological differences by sex and intestinal microbiome.

1 Mar 2023

What is the role of B cells in breast cancer pathology?

In a recent study published in Cancers, researchers comprehensively summarized all available information about B cells in the context of breast cancer.

1 Mar 2023

UVA research provides new insight into common causes of vision loss

UVA Health scientists have discovered an unknown contributor to harmful blood vessel growth in the eye that could lead to new treatments for blinding macular degeneration and other common causes of vision loss.

24 Feb 2023

Synthetic hydrogels enable neuronal tissue growth in areas of brain damage

Synthetic hydrogels were shown to provide an effective scaffold for neuronal tissue growth in areas of brain damage, providing a possible approach for brain tissue reconstruction.

24 Feb 2023

Study identifies placental growth factor as a biomarker for vascular cognitive impairment

Measuring a key blood molecule may help doctors diagnose whether or how much impaired blood flow to a patient's brain is contributing to dementia or cognitive problems, according to a new study led by a UCLA Health researcher.

23 Feb 2023

Study investigates anti-VEGF treatment for inflammatory eye disease in HTLV-1–infected ocular cells

A retrovirus known as human T-cell lymphotropic virus type 1 (HTLV-1) is known to cause a number of diseases, including inflammatory diseases of the eye. Recently, researchers in Japan have investigated an antibody treatment for inflammatory eye disease in ocular cells infected with HTLV-1.

21 Feb 2023

Penn engineers address the longstanding gap in reproductive health care with targeted RNA therapy

Pre-eclampsia is a leading cause of stillbirths and prematurity worldwide, occurring in 3 – 8 % of pregnancies. A disorder characterized by high maternal blood pressure, it results from insufficient vasodilation in the placenta, restricting blood flow from the mother to the fetus.

16 Feb 2023

Active compound in Lion’s Mane mushroom improves nerve growth and memory

Scientists report that the active compound from an edible mushroom, Hericium erinaceus, can enhance nerve growth and boost memory.

13 Feb 2023

EGFR protein plays a decisive role in the penetration of hepatitis E virus into cells

A certain surface protein is crucial to allow the hepatitis E virus to enter cells. Medication can suppress it.

9 Feb 2023

Growth Factor News and Research

Study finds better breast cancer screening outcomes with tomosynthesis than mammography

Correcting abnormalities in solid tumor's blood vessels can improve efficacy of CAR-T cell therapy

Distinct microbial profile present in intrahepatic cholestasis of pregnancy patients

SARS-CoV-2 replication persists for weeks in lungs after symptom onset in severe COVID-19

Abnormally low autoantibody activity significantly associated with autism severity

What is the effect of low Anti-Müllerian hormone on semen quality?

Cancer stage and receptor status influence the risk of breast cancer recurrence

Nasal administration of a fully human anti-CD3 monoclonal antibody modulates T cell inflammatory responses in COVID-19

A shot of liver-produced hormone sobers up drunk mice

Multi-organ scRNA-seq reveals targeting pro- or anti-inflammatory regulators may be exploited for personalized treatment of immune diseases

Research investigates roles of neurotrophic factors on cognition in Alzheimer's patients carrying APOE ε4

Study reveals synergistic impact of estrogen and intestinal dysbiosis on pulmonary fibrosis

What is the role of B cells in breast cancer pathology?

UVA research provides new insight into common causes of vision loss

Synthetic hydrogels enable neuronal tissue growth in areas of brain damage

Study identifies placental growth factor as a biomarker for vascular cognitive impairment

Study investigates anti-VEGF treatment for inflammatory eye disease in HTLV-1–infected ocular cells

Penn engineers address the longstanding gap in reproductive health care with targeted RNA therapy

Active compound in Lion’s Mane mushroom improves nerve growth and memory

EGFR protein plays a decisive role in the penetration of hepatitis E virus into cells

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Why use light scattering to analyze proteins and viral vectors?

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