Stem Cells News and Research

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Stem cells have the remarkable potential to develop into many different cell types in the body during early life and growth. In addition, in many tissues they serve as a sort of internal repair system, dividing essentially without limit to replenish other cells as long as the person or animal is still alive. When a stem cell divides, each new cell has the potential either to remain a stem cell or become another type of cell with a more specialized function, such as a muscle cell, a red blood cell, or a brain cell.

Cellular roadmap offers new targets for improving rotator cuff surgical repair

Rotator cuff tears are among the most common and debilitating musculoskeletal injuries, frequently causing chronic pain, reduced shoulder mobility, and a high risk of re-injury even after surgical repair.

9 Mar 2026

Targeting Wnt signaling to solve the dental pulp challenge

Dental pulp regeneration remains a major clinical challenge. Researchers have discovered that SMAD7 directly forms a transcriptional complex with β-catenin in human dental pulp stem cells, activating Wnt signaling and promoting regenerative gene expression.

9 Mar 2026

AI trained on 9 trillion DNA letters predicts harmful mutations and designs new genomes

Scientists developed Evo 2, a large biological foundation model trained on about 9 trillion DNA base pairs that can analyse genomic sequences across bacteria, plants, and humans. The model predicts functional effects of genetic variants and can generate genome-scale DNA sequences, enabling new approaches to studying and designing biological systems.

5 Mar 2026

Study sheds light on potential therapeutic strategies for post-traumatic osteoarthritis

Post-traumatic osteoarthritis often affects younger, active individuals and progresses quickly following ligament or cartilage injury.

4 Mar 2026

3D-printed scaffolds use shape memory to heal infected bone defects

Infected bone defects arise in conditions such as osteomyelitis and post-traumatic bone infections, where microbial persistence and immune imbalance prevent effective healing.

4 Mar 2026

Researchers identify TRIM13 protein as key driver of immune suppression in sepsis

Dendritic cells (DCs) are increasingly recognized as important contributors to sepsis-associated immune dysfunction.

4 Mar 2026

Stem cells from human primary tooth pulp may help treat chronic-phase cerebral palsy

Cerebral palsy is a condition usually caused by brain damage before or during birth, resulting in impaired posture and movement.

4 Mar 2026

Gut microbiota-derived metabolite directly shapes immune responses in bacterial pneumonia

Sepsis and severe pneumonia are frequently accompanied by disruption of the gut microbiota, leading to immune dysfunction and increased susceptibility to secondary infections.

4 Mar 2026

Iron found essential for growth and survival of beta cells

An international team of scientists, led by researchers from the Free University of Brussels (VUB) and UZ Brussel, has made a major breakthrough in the study of how our bodies maintain healthy blood sugar levels.

3 Mar 2026

NLRP3 inflammasome plays dual, time-dependent roles during acute wound healing

Wound healing is a multistep biological process involving inflammation, tissue formation, and remodeling.

2 Mar 2026

ATP delivery fixes dysfunctional dopamine packaging in Parkinson's neurons

A new study shows how dysfunctional packaging of the neurotransmitter dopamine triggers toxic processes in neurons - and how this can be repaired with simple delivery of energy (ATP).

2 Mar 2026

Scientists discover how muscle stem cells "flip a switch" to rebuild damaged muscle

Scientists at the University of California, Irvine's School of Pharmacy & Pharmaceutical Sciences have discovered how muscle stem cells "flip a switch" to rebuild damaged muscle – a finding that could help address muscle loss linked to aging, injury and widely used weight-loss medications.

27 Feb 2026

Combining stem cell therapy with fetal surgery shows promise for treating myelomeningocele

A phase 1 clinical trial published in The Lancet has shown that combining stem cell therapy with standard fetal surgery before birth is a safe and promising approach to treat myelomeningocele, a severe form of spina bifida.

26 Feb 2026

Researchers reveal why SuperAgers retain youthful brain cell signatures into their 80s

Researchers used single-nucleus RNA sequencing and chromatin accessibility profiling to map human hippocampal neurogenesis across adulthood, aging, and Alzheimer’s disease. They found that chromatin accessibility changes, more than gene expression alone, distinguish healthy aging, preclinical pathology, Alzheimer’s disease, and cognitive resilience in SuperAgers.

26 Feb 2026

Reducing miRNA levels helps rescue vascular defects in Rett syndrome

MIT researchers have discovered that two common genetic mutations that cause Rett syndrome each set off a molecular chain of events that compromises the structural integrity of developing brain blood vessels, making them leaky.

25 Feb 2026

Superagers show greater neuron growth linked to strong memory

Brains of older adults with super healthy cognition grow more new neurons than those of their peers, according to a study from UIC, Northwestern University and the University of Washington.

25 Feb 2026

Breakthrough gene therapy for sickle cell disease remains out of reach in Africa

As Uganda rolls out mandatory nationwide screening of newborns for sickle cell disease this month, a gene therapy celebrated in the United States and Europe remains financially out of reach for most patients in Africa.

25 Feb 2026

Genetic mismatch identified as major risk factor in cord blood transplantation

A Japanese study of more than 7,400 patients has identified a genetic mismatch that sharply increases the risk of severe acute graft-versus-host disease (GVHD) following umbilical cord blood transplantation.

20 Feb 2026

Embryonic reproductive cells reveal striking genomic architecture before development

Researchers at the MRC Laboratory of Medical Sciences (LMS) and Imperial College London have shown for the first time that, before they can start developing into egg and sperm cells, the embryonic precursors of these cells uniquely reshape the 3D organization of their genetic material.

20 Feb 2026

Brain organoids show goal-directed learning in control task

Imagine balancing a ruler vertically in the palm of your hand: you have to constantly pay attention to the angle of the ruler and make many small adjustments to make sure it doesn't fall over. It takes practice to get good at this.

19 Feb 2026

Stem Cells News and Research

Further Reading

Cellular roadmap offers new targets for improving rotator cuff surgical repair

Targeting Wnt signaling to solve the dental pulp challenge

AI trained on 9 trillion DNA letters predicts harmful mutations and designs new genomes

Study sheds light on potential therapeutic strategies for post-traumatic osteoarthritis

3D-printed scaffolds use shape memory to heal infected bone defects

Researchers identify TRIM13 protein as key driver of immune suppression in sepsis

Stem cells from human primary tooth pulp may help treat chronic-phase cerebral palsy

Gut microbiota-derived metabolite directly shapes immune responses in bacterial pneumonia

Iron found essential for growth and survival of beta cells

NLRP3 inflammasome plays dual, time-dependent roles during acute wound healing

ATP delivery fixes dysfunctional dopamine packaging in Parkinson's neurons

Scientists discover how muscle stem cells "flip a switch" to rebuild damaged muscle

Combining stem cell therapy with fetal surgery shows promise for treating myelomeningocele

Researchers reveal why SuperAgers retain youthful brain cell signatures into their 80s

Reducing miRNA levels helps rescue vascular defects in Rett syndrome

Superagers show greater neuron growth linked to strong memory

Breakthrough gene therapy for sickle cell disease remains out of reach in Africa

Genetic mismatch identified as major risk factor in cord blood transplantation

Embryonic reproductive cells reveal striking genomic architecture before development

Brain organoids show goal-directed learning in control task

eBook: Integrated solutions for mesenchymal stem cell research and culture eBook

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Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

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